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Select item 107587371.

JAK2^V617F mutation and associated chromosomal alterations in primary and secondary myelofibrosis and post-HCT outcomes

Maryam Rafati, Derek W. Brown, Weiyin Zhou, Kristine Jones, Wen Luo, Andrew St. Martin, Youjin Wang, Meilun He, Stephen R. Spellman, Tao Wang, H. Joachim Deeg, Vikas Gupta, Stephanie J. Lee, Yung-Tsi Bolon, Stephen J. Chanock, Mitchell J. Machiela, Wael Saber, Shahinaz M. Gadalla

Blood Adv. 2023 Dec 26; 7(24): 7506–7515. Published online 2023 Oct 29. doi: 10.1182/bloodadvances.2023010882

PMCID:: PMC10758737

Abstract Article PDF–855K

Select item 104175542.

Clinical Characteristics and Outcomes of Patients with Primary and Secondary Myelofibrosis According to the Genomic Classification Using Targeted Next-Generation Sequencing

Marta Garrote, Mónica López-Guerra, Eduardo Arellano-Rodrigo, María Rozman, Sara Carbonell, Francesca Guijarro, Marta Santaliestra, Ana Triguero, Dolors Colomer, Francisco Cervantes, Alberto Álvarez-Larrán

Cancers (Basel) 2023 Aug; 15(15): 3904. Published online 2023 Jul 31. doi: 10.3390/cancers15153904

PMCID:: PMC10417554

Abstract Article PDF–1.6M

Select item 95900593.

A Case Report on Hepatic Extramedullary Hematopoiesis as the Manifestation of Progression to Secondary Myelofibrosis in a Patient with Essential Thrombocytopenia

Kaitlin I. McArthur, Philip N. Papayanis, Michael H. K. Nguyen, Yahya Daneshbod, Mojtaba Akhtari

Hematol Rep. 2022 Dec; 14(4): 286–289. Published online 2022 Sep 21. doi: 10.3390/hematolrep14040040

PMCID:: PMC9590059

Abstract Article PDF–210K

Select item 88163774.

Early Mixed Lymphoid Donor/Host Chimerism is Associated with Improved Transplant Outcome in Patients with Primary or Secondary Myelofibrosis

H. Joachim Deeg, Rachel B. Salit, Tim Monahan, Gary Schoch, Chris McFarland, Bart L. Scott, Barry E. Storer

Biol Blood Marrow Transplant. Author manuscript; available in PMC 2022 Feb 4.

Published in final edited form as: Biol Blood Marrow Transplant. 2020 Dec; 26(12): 2197–2203. Published online 2020 Jul 18. doi: 10.1016/j.bbmt.2020.07.013

PMCID:: PMC8816377

Abstract Article PDF–774K

Select item 81489855.

Phase 1/2 trial of glasdegib in patients with primary or secondary myelofibrosis previously treated with ruxolitinib

Aaron T. Gerds, Tetsuzo Tauchi, Ellen Ritchie, Michael Deininger, Catriona Jamieson, Ruben Mesa, Mark Heaney, Norio Komatsu, Hironobu Minami, Yun Su, Naveed Shaik, Xiaoxi Zhang, Christine DiRienzo, Mirjana Zeremski, Geoffrey Chan, Moshe Talpaz

Leuk Res. Author manuscript; available in PMC 2021 May 25.

Published in final edited form as: Leuk Res. 2019 Apr; 79: 38–44. Published online 2019 Feb 28. doi: 10.1016/j.leukres.2019.02.012

Correction in:: Leuk Res. 2019 Jun; 81: 105.

PMCID:: PMC8148985

Abstract Article PDF–500K

Select item 79482606.

Genomic analysis of primary and secondary myelofibrosis redefines the prognostic impact of ASXL1 mutations: a FIM study

Damien Luque Paz, Jérémie Riou, Emmanuelle Verger, Bruno Cassinat, Aurélie Chauveau, Jean-Christophe Ianotto, Brigitte Dupriez, Françoise Boyer, Maxime Renard, Olivier Mansier, Anne Murati, Jérôme Rey, Gabriel Etienne, Véronique Mansat-De Mas, Suzanne Tavitian, Olivier Nibourel, Stéphane Girault, Yannick Le Bris, François Girodon, Dana Ranta, Jean-Claude Chomel, Pascale Cony-Makhoul, Pierre Sujobert, Margot Robles, Raouf Ben Abdelali, Olivier Kosmider, Laurane Cottin, Lydia Roy, Ivan Sloma, Fabienne Vacheret, Mathieu Wemeau, Pascal Mossuz, Borhane Slama, Vincent Cussac, Guillaume Denis, Anouk Walter-Petrich, Barbara Burroni, Nathalie Jézéquel, Stéphane Giraudier, Eric Lippert, Gérard Socié, Jean-Jacques Kiladjian, Valérie Ugo

Blood Adv. 2021 Mar 9; 5(5): 1442–1451. Published online 2021 Mar 5. doi: 10.1182/bloodadvances.2020003444

PMCID:: PMC7948260

Abstract Article PDF–1.1M

Select item 72321177.

The role of fedratinib for the treatment of patients with primary or secondary myelofibrosis

Jeanne Palmer, Ruben Mesa

Ther Adv Hematol. 2020; 11: 2040620720925201. Published online 2020 May 15. doi: 10.1177/2040620720925201

PMCID:: PMC7232117

Abstract Article PDF–486K

Select item 60208698.

Numb chin syndrome as a presenting symptom of diffuse large B-cell lymphoma with secondary myelofibrosis

Arihant Jain, Sweta Rajpal, Man Updesh Singh Sachdeva, Pankaj Malhotra

BMJ Case Rep. 2018; 2018: bcr2017221245. Published online 2018 Jun 21. doi: 10.1136/bcr-2017-221245

PMCID:: PMC6020869

Abstract Article PDF–665K

Select item 108374589.

Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms

Kristin Holl, Nicolas Chatain, Susanne Krapp, Julian Baumeister, Tiago Maié, Sarah Schmitz, Anja Scheufen, Nathalie Brock, Steffen Koschmieder, Daniel Moreno-Andrés

Sci Rep. 2024; 14: 2810. Published online 2024 Feb 2. doi: 10.1038/s41598-024-53240-8

PMCID:: PMC10837458

Abstract Article PDF–3.9M

Select item 1074407810.

Myeloproliferative Neoplasms: Contemporary Review and Molecular Landscape

Muftah Mahmud, Swati Vasireddy, Krisstina Gowin, Akshay Amaraneni

Int J Mol Sci. 2023 Dec; 24(24): 17383. Published online 2023 Dec 12. doi: 10.3390/ijms242417383

PMCID:: PMC10744078

Abstract Article PDF–1.2M

Select item 1062056111.

Momelotinib (JAK1/JAK2/ACVR1 inhibitor): mechanism of action, clinical trial reports, and therapeutic prospects beyond myelofibrosis

Ayalew Tefferi, Animesh Pardanani, Naseema Gangat

Haematologica. 2023 Nov 1; 108(11): 2919–2932. Published online 2023 Mar 2. doi: 10.3324/haematol.2022.282612

PMCID:: PMC10620561

Abstract Article PDF–4.6M

Select item 1015261612.

Higher estimated plasma volume status is associated with increased thrombotic risk and impaired survival in patients with primary myelofibrosis

Marko Lucijanic, Ivan Krecak, Ena Soric, Anica Sabljic, Davor Galusic, Hrvoje Holik, Vlatka Perisa, Martina Moric Peric, Ivan Zekanovic, Rajko Kusec

Biochem Med (Zagreb) 2023 Jun 15; 33(2): 020901. Published online 2023 Apr 15. doi: 10.11613/BM.2023.020901

PMCID:: PMC10152616

Abstract Article PDF–198K

Select item 998952213.

Patient-specific comorbidities as prognostic variables for survival in myelofibrosis

Andrew L. Sochacki, Cosmin Adrian Bejan, Shilin Zhao, Ameet Patel, Ashwin Kishtagari, Travis P. Spaulding, Alexander J. Silver, Shannon S. Stockton, Kelly Pugh, R. Dixon Dorand, Manasa Bhatta, Nicholas Strayer, Siwei Zhang, Christina A. Snider, Thomas Stricker, Aziz Nazha, Alexander G. Bick, Yaomin Xu, Michael R. Savona

Blood Adv. 2023 Mar 14; 7(5): 756–767. Published online 2022 Apr 18. doi: 10.1182/bloodadvances.2021006318

PMCID:: PMC9989522

Abstract Article PDF–462K

Select item 974001714.

Novel Molecular Insights into Leukemic Evolution of Myeloproliferative Neoplasms: A Single Cell Perspective

Sebastiano Rontauroli, Chiara Carretta, Sandra Parenti, Matteo Bertesi, Rossella Manfredini

Int J Mol Sci. 2022 Dec; 23(23): 15256. Published online 2022 Dec 3. doi: 10.3390/ijms232315256

PMCID:: PMC9740017

Abstract Article PDF–2.3M

Select item 915305115.

Anti-inflammatory treatment in MPN: targeting TNFR1 and TNFR2 in JAK2-V617F–induced disease

Peter Müller, Conny K. Baldauf, Tobias R. Haage, Ana M. Waldleben, Fabian Richter, Klaus Pfizenmaier, Thomas Fischer

Blood Adv. 2021 Dec 14; 5(23): 5349–5359. Published online 2021 Dec 9. doi: 10.1182/bloodadvances.2021004438

PMCID:: PMC9153051

Abstract Article PDF–1.8M

Select item 910275516.

Rapid progression of myelofibrosis in polycythemia vera patient carrying SRSF2 c.284C>A p.(Pro95His) and unique ASXL1 splice site c.1720‐2A>G variant

Zuzanna Kanduła, Renata Kroll‐Balcerzak, Krzysztof Lewandowski

J Clin Lab Anal. 2022 May; 36(5): e24388. Published online 2022 Apr 18. doi: 10.1002/jcla.24388

PMCID:: PMC9102755

Abstract Article PDF–1.4M

Select item 886464617.

Reduced intensity hematopoietic stem cell transplantation for accelerated-phase myelofibrosis

Nico Gagelmann, Christine Wolschke, Rachel B. Salit, Thomas Schroeder, Markus Ditschkowski, Victoria Panagiota, Bruno Cassinat, Felicitas Thol, Anita Badbaran, Marie Robin, Hans Christian Reinhardt, Francis Ayuk, Michael Heuser, Bart L. Scott, Nicolaus Kröger

Blood Adv. 2022 Feb 22; 6(4): 1222–1231. Published online 2022 Feb 16. doi: 10.1182/bloodadvances.2021006827

PMCID:: PMC8864646

Abstract Article PDF–1.1M

Select item 842137318.

Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia

Tadaaki Inano, Marito Araki, Soji Morishita, Misa Imai, Yoshihiko Kihara, Maho Okuda, Yinjie Yang, Masafumi Ito, Satoshi Osaga, Hiroyuki Mano, Yoko Edahiro, Tomonori Ochiai, Kyohei Misawa, Yasutaka Fukuda, Jun Ando, Norio Komatsu

Sci Rep. 2021; 11: 17702. Published online 2021 Sep 6. doi: 10.1038/s41598-021-97106-9

Correction in:: Sci Rep. 2022; 12: 1115.

PMCID:: PMC8421373

Abstract Article PDF–2.1M

Select item 794826719.

Gene expression profile correlates with molecular and clinical features in patients with myelofibrosis

Sebastiano Rontauroli, Sara Castellano, Paola Guglielmelli, Roberta Zini, Elisa Bianchi, Elena Genovese, Chiara Carretta, Sandra Parenti, Sebastian Fantini, Selene Mallia, Lara Tavernari, Stefano Sartini, Margherita Mirabile, Carmela Mannarelli, Francesca Gesullo, Annalisa Pacilli, Daniela Pietra, Elisa Rumi, Silvia Salmoiraghi, Barbara Mora, Laura Villani, Andrea Grilli, Vittorio Rosti, Giovanni Barosi, Francesco Passamonti, Alessandro Rambaldi, Luca Malcovati, Mario Cazzola, Silvio Bicciato, Enrico Tagliafico, Alessandro M. Vannucchi, Rossella Manfredini

Blood Adv. 2021 Mar 9; 5(5): 1452–1462. Published online 2021 Mar 5. doi: 10.1182/bloodadvances.2020003614

PMCID:: PMC7948267

Abstract Article PDF–1.2M

Select item 755662420.

Ruxolitinib and interferon-α2 combination therapy for patients with polycythemia vera or myelofibrosis: a phase II study

Anders Lindholm Sørensen, Stine Ulrik Mikkelsen, Trine Alma Knudsen, Mads Emil Bjørn, Christen Lykkegaard Andersen, Ole Weis Bjerrum, Nana Brochmann, Dustin Andersen Patel, Lise Mette Rahbek Gjerdrum, Daniel El Fassi, Torben A. Kruse, Thomas Stauffer Larsen, Hans Torben Mourits-Andersen, Claus Henrik Nielsen, Christina Ellervik, Niels Pallisgaard, Mads Thomassen, Lasse Kjær, Vibe Skov, Hans Carl Hasselbalch

Haematologica. 2020 Sep 1; 105(9): 2262–2272. Published online 2020 Jan 16. doi: 10.3324/haematol.2019.235648

PMCID:: PMC7556624

Abstract Article PDF–2.3M

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