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Select item 110798681.

Synthesis of Novel Hydrazide–Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II

Reşit Çakmak, Eyüp Başaran, Kader Sahin, Murat Şentürk, Serdar Durdağı

ACS Omega. 2024 May 7; 9(18): 20030–20041. Published online 2024 Apr 26. doi: 10.1021/acsomega.3c10182

PMCID:: PMC11079868

Abstract Article PDF–4.3M

Select item 110034812.

Synthesis, biological evaluation, and computational studies of N-benzyl pyridinium–curcumin derivatives as potent AChE inhibitors with antioxidant activity

Nafisah M. Al-Rifai, Nemeh M. Al-Khalileh, Jalal A. Zahra, Musa I. El-Barghouthi, Fouad H. Darras

J Enzyme Inhib Med Chem. 2023; 38(1): 2281264. Published online 2023 Nov 20. doi: 10.1080/14756366.2023.2281264

PMCID:: PMC11003481

Abstract Article PDF–1.3M

Select item 109555713.

Small Peptides Targeting BACE-1, AChE, and A-β Reversing Scopolamine-Induced Memory Impairment: A Multitarget Approach against Alzheimer’s Disease

Baljit Kaur, Rajbir Kaur, Vivesh, Sudesh Rani, Rajbir Bhatti, Palwinder Singh

ACS Omega. 2024 Mar 19; 9(11): 12896–12913. Published online 2024 Mar 4. doi: 10.1021/acsomega.3c09069

PMCID:: PMC10955571

Abstract Article PDF–13M

Select item 109417744.

Molecular docking analysis of flavonoids with AChE and BACE-1

Sittarthan Viswanathan, Thennavan Arumugam, Kavimani Subramanian, Rengaraj Sivaraj, Vimalavathini Ramesh, A. Hannah Rachel Vasanthi

Bioinformation. 2024; 20(2): 103–109. Published online 2024 Feb 29. doi: 10.6026/973206300200103

PMCID:: PMC10941774

Abstract Article PDF–742K

Select item 109217395.

PLA2G4A and ACHE modulate lipid profiles via glycerophospholipid metabolism in platinum-resistant gastric cancer

Menglin Chen, Cancan Zhang, Huaizhi Li, Shanshan Zheng, Yaqi Li, Mengyun Yuan, Yuxuan Chen, Jian Wu, Qingmin Sun

J Transl Med. 2024; 22: 249. Published online 2024 Mar 7. doi: 10.1186/s12967-024-05055-4

PMCID:: PMC10921739

Abstract Article PDF–5.6M

Select item 108234236.

Synthesis, biological evaluation and molecular docking of novel nereistoxin derivatives containing phosphonates as insecticidal/AChE inhibitory agents

Qiaoli Yan, Xiaogang Lu, Jin Wang, Zixuan Zhang, Runli Gao, Chengxin Pei, Hongmei Wang

RSC Adv. 2024 Jan 23; 14(6): 3996–4004. Published online 2024 Jan 29. doi: 10.1039/d3ra08004h

PMCID:: PMC10823423

Abstract Article PDF–836K

Select item 108208907.

Potential of Tryptamine Derivatives as Multi-Target Directed Ligands for Alzheimer’s Disease: AChE, MAO-B, and COX-2 as Molecular Targets

Saira Asghar, Nousheen Mushtaq, Ahsaan Ahmed, Laila Anwar, Rabya Munawar, Shamim Akhtar

Molecules. 2024 Jan; 29(2): 490. Published online 2024 Jan 19. doi: 10.3390/molecules29020490

PMCID:: PMC10820890

Abstract Article PDF–3.7M

Select item 106937198.

“It Makes You Feel Alive and Younger…but It’s Stressful …My Back and Legs Ache”: A Focus Group Study Encouraging Resistance Training Around Retirement

Rachael Frost, Anna Lowe, Snehal M. Pinto Pereira

J Appl Gerontol. 2024 Jan; 43(1): 59–68. Published online 2023 Sep 12. doi: 10.1177/07334648231193562

PMCID:: PMC10693719

Abstract Article PDF–603K

Select item 105824569.

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

Zhonghui Zhang, Zhichao Liu, Peicong Wu, Xinhua Guo, Xiao Luo, Youjun Yang, Jinquan Chen, Yang Tian

Adv Sci (Weinh) 2023 Oct; 10(29): 2301004. Published online 2023 Aug 27. doi: 10.1002/advs.202301004

PMCID:: PMC10582456

Abstract Article PDF–3.2M

Select item 1057375210.

New Benzamides as Multi-Targeted Compounds: A Study on Synthesis, AChE and BACE1 Inhibitory Activity and Molecular Docking

Danuta Drozdowska, Dawid Maliszewski, Agnieszka Wróbel, Artur Ratkiewicz, Michał Sienkiewicz

Int J Mol Sci. 2023 Oct; 24(19): 14901. Published online 2023 Oct 4. doi: 10.3390/ijms241914901

PMCID:: PMC10573752

Abstract Article PDF–3.8M

Select item 1057339011.

Identification of ACHE as the hub gene targeting solasonine associated with non-small cell lung cancer (NSCLC) using integrated bioinformatics analysis

Tong Liu, Boke Zhang, Yating Gao, Xingxing Zhang, Jiabing Tong, Zegeng Li

PeerJ. 2023; 11: e16195. Published online 2023 Oct 10. doi: 10.7717/peerj.16195

PMCID:: PMC10573390

Abstract Article PDF–11M

Select item 1056996212.

Nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, COX-2, and diminution of AChE, BDNF and NGF levels in cerebral cortex and hippocampus of male albino rats

Chidinma P. Anyachor, Chinna N. Orish, Anthonet N. Ezejiofor, Ana Cirovic, Aleksandar Cirovic, Kenneth M. Ezealisiji, Orish E. Orisakwe

Curr Res Toxicol. 2023; 5: 100129. Published online 2023 Oct 2. doi: 10.1016/j.crtox.2023.100129

PMCID:: PMC10569962

Abstract Article PDF–773K

Select item 1053121913.

Evaluation of GSTP1, GSTA4 and AChE Gene Methylation in Bovine Lymphocytes Cultured In Vitro with Miconazole Alone and in Combination with Mospilan 20SP

Jana Halušková, Beáta Holečková, Viera Schwarzbacherová, Martina Galdíková, Silvia Sedláková, Jaroslav Bučan

Genes (Basel) 2023 Sep; 14(9): 1791. Published online 2023 Sep 12. doi: 10.3390/genes14091791

PMCID:: PMC10531219

Abstract Article PDF–573K

Select item 1052915114.

Sevoflurane inhalation has a cognitive impairing effect of aging rats involving the regulation of AChE and ChAT

Xin‐Xin Yang, Zhen‐Yu Wu, Yang Yang, Chao Zhang, Xia‐Fei Lin, Lin Zhou, Feng‐Lin Wang, Liang Dong, Zhao‐Qiong Zhu

Ibrain. 2021 Sep; 7(3): 192–199. Published online 2021 Sep 28. doi: 10.1002/j.2769-2795.2021.tb00083.x

PMCID:: PMC10529151

Abstract Article PDF–464K

Select item 1052240215.

Investigating the Link Between Low Back Ache, Abdominal Discomfort and Oliguria: A Unique Case of Histopathology-Proven Retroperitoneal Fibrosis

Jithin Vijayan, Hrishikesh Bora, Amir Ali, Devika K R

Cureus. 2023 Aug; 15(8): e44220. Published online 2023 Aug 27. doi: 10.7759/cureus.44220

PMCID:: PMC10522402

Abstract Article PDF–1.6M

Select item 1050638316.

Microwave-assisted commercial copper-catalyzed aerobic oxidative synthesis of AChE quinazolinone inhibitors under solvent free conditions

Jira Jongcharoenkamol, Prakansi Naksing, Nattayaporn Nimnuan, Thishana Singh, Jaruwan Chatwichien, Prapapan Temkitthawon, Chanitsara Sriwattanawarunyoo, Vachira Choommongkol, Puttinan Meepowpan, Sutthichat Kerdphon

RSC Adv. 2023 Sep 8; 13(39): 27657–27662. Published online 2023 Sep 18. doi: 10.1039/d3ra05739a

PMCID:: PMC10506383

Abstract Article PDF–646K

Select item 1045898117.

Network Toxicology and Molecular Docking to Investigate the Non-AChE Mechanisms of Organophosphate-Induced Neurodevelopmental Toxicity

Juliana Alves da Costa Ribeiro Souza, Terezinha Souza, Isadora Louise Alves da Costa Ribeiro Quintans, Davi Farias

Toxics. 2023 Aug; 11(8): 710. Published online 2023 Aug 17. doi: 10.3390/toxics11080710

PMCID:: PMC10458981

Abstract Article PDF–18M

Select item 1042127018.

Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity

Marco Paolino, Modesto de Candia, Rosa Purgatorio, Marco Catto, Mario Saletti, Anna Rita Tondo, Orazio Nicolotti, Andrea Cappelli, Antonella Brizzi, Claudia Mugnaini, Federico Corelli, Cosimo D. Altomare

Molecules. 2023 Aug; 28(15): 5857. Published online 2023 Aug 3. doi: 10.3390/molecules28155857