PMC Links for GEO Profiles (Select 99176798) - PMC

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90978444.

ASIC1a stimulates the resistance of human hepatocellular carcinoma by promoting EMT via the AKT/GSK3β/Snail pathway driven by TGFβ/Smad signals

Yinci Zhang, Niandie Cao, Jiafeng Gao, Jiaojiao Liang, Yong Liang, Yinghai Xie, Shuping Zhou, Xiaolong Tang

J Cell Mol Med. 2022 May; 26(10): 2777–2792. Published online 2022 Apr 14. doi: 10.1111/jcmm.17288

PMCID:: PMC9097844

Abstract Article PDF–54M

Select item 87159815.

Upregulation of acid sensing ion channels is associated with esophageal hypersensitivity in GERD

Xu Han, Yawen Zhang, Allen Lee, Zhaoshen Li, Jun Gao, Xiaoyin Wu, Jiulong Zhao, Hui Wang, Di Chen, Duowu Zou, Chung Owyang

FASEB J. 2022 Jan; 36(1): e22083. Published online 2021 Dec 17. doi: 10.1096/fj.202100606R

PMCID:: PMC8715981

Abstract Article PDF–1.6M

Select item 85529076.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 84485447.

Regulation of gliomagenesis and stemness through acid sensor ASIC1a

Pendelton King, Jingwei Wan, Alyssa Aihui Guo, Shanchun Guo, Yugang Jiang, Mingli Liu

Int J Oncol. 2021 Oct; 59(4): 82. Published online 2021 Sep 10. doi: 10.3892/ijo.2021.5262

PMCID:: PMC8448544

Abstract Article PDF–2.4M

Select item 83185898.

Structure and analysis of nanobody binding to the human ASIC1a ion channel

Yangyu Wu, Zhuyuan Chen, Fred J Sigworth, Cecilia M Canessa

eLife. 2021; 10: e67115. Published online 2021 Jul 28. doi: 10.7554/eLife.67115

PMCID:: PMC8318589

Abstract Article PDF–5.7M

Select item 81996449.

Expression Profiles of ASIC1/2 and TRPV1/4 in Common Skin Tumors

Kirsten Ackermann, Susanne Wallner, Christoph Brochhausen, Stephan Schreml

Int J Mol Sci. 2021 Jun; 22(11): 6024. Published online 2021 Jun 2. doi: 10.3390/ijms22116024

PMCID:: PMC8199644

Abstract Article PDF–68M

Select item 816788910.

Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1

Matthew L. Rook, Megan Miaro, Tyler Couch, Dana L. Kneisley, Maria Musgaard, David M. MacLean

J Gen Physiol. 2021 Aug 2; 153(8): e202012855. Published online 2021 Jun 1. doi: 10.1085/jgp.202012855

PMCID:: PMC8167889

Abstract Article PDF–3.2M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806422312.

ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration

Jingyu Ding, Renjie Zhang, Huimin Li, Qiang Ji, Xiaomin Cheng, Rick Francis Thorne, Hubert Hondermarck, Xiaoying Liu, Cailiang Shen

Aging (Albany NY) 2021 Apr 15; 13(7): 10703–10723. Published online 2021 Apr 6. doi: 10.18632/aging.202850

PMCID:: PMC8064223

Abstract Article PDF–2.0M

Select item 800967913.

Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate

Sabrina Vullo, Nicolas Ambrosio, Jan P Kucera, Olivier Bignucolo, Stephan Kellenberger

eLife. 2021; 10: e66488. Published online 2021 Mar 17. doi: 10.7554/eLife.66488

PMCID:: PMC8009679

Abstract Article PDF–6.0M

Select item 797970514.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 787632215.

Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Target for Rheumatoid Arthritis

Yayun Xu, Feihu Chen

Front Immunol. 2020; 11: 580936. Published online 2021 Jan 28. doi: 10.3389/fimmu.2020.580936

PMCID:: PMC7876322

Abstract Article PDF–937K

Select item 787074216.

Postsynaptic Targeting and Mobility of Membrane Surface-Localized hASIC1a

Xing-Lei Song, Di-Shi Liu, Min Qiang, Qian Li, Ming-Gang Liu, Wei-Guang Li, Xin Qi, Nan-Jie Xu, Guang Yang, Michael Xi Zhu, Tian-Le Xu

Neurosci Bull. 2021 Feb; 37(2): 145–165. Published online 2020 Sep 30. doi: 10.1007/s12264-020-00581-9

PMCID:: PMC7870742

Abstract Article PDF–4.6M

Select item 755377917.

Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1

Demeng Sun, Sanling Liu, Siyu Li, Mengge Zhang, Fan Yang, Ming Wen, Pan Shi, Tao Wang, Man Pan, Shenghai Chang, Xing Zhang, Longhua Zhang, Changlin Tian, Lei Liu

eLife. 2020; 9: e57096. Published online 2020 Sep 11. doi: 10.7554/eLife.57096

PMCID:: PMC7553779

Abstract Article PDF–3.1M

Select item 732206718.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 716998319.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 685150720.

ASIC1a activation induces calcium-dependent apoptosis of BMSCs under conditions that mimic the acidic microenvironment of the degenerated intervertebral disc

Feng Cai, Xin Hong, Xiang Tang, Nai-Cheng Liu, Feng Wang, Lei Zhu, Xin-Hui Xie, Zhi-Yang Xie, Xiao-Tao Wu

Biosci Rep. 2019 Nov 29; 39(11): BSR20192708. Published online 2019 Nov 13. doi: 10.1042/BSR20192708

PMCID:: PMC6851507

Abstract Article PDF–2.9M

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