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Items: 1 to 20 of 69

1.
Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury
Ke Lai, Iva Pritišanac, Zhen-Qi Liu, Han-Wei Liu, Li-Na Gong, Ming-Xian Li, Jian-Fei Lu, Xin Qi, Tian-Le Xu, Julie Forman-Kay, Hai-Bo Shi, Lu-Yang Wang, Shan-Kai Yin
Nature. 2024; 631(8022): 826–834. Published online 2024 Jul 10. doi: 10.1038/s41586-024-07684-7
PMCID:
PMC11269185
AbstractArticlePDF–17M
2.
The roles of acid-sensing ion channel 1a and ovarian cancer G protein-coupled receptor 1 on passive Mg2+ transport across intestinal epithelium-like Caco-2 monolayers
Narongrit Thongon, Pattamaporn Ketkeaw, Chanin Nuekchob
J Physiol Sci. 2014 Mar; 64(2): 129–139. Published online 2013 Dec 28. doi: 10.1007/s12576-013-0301-8
PMCID:
PMC10717441
AbstractArticlePDF–1.2M
3.
ASIC1a Involves the Acid-Mediated Activation of Pancreatic Stellate Cells Associated With Autophagy Induction
Tao WANG, Qianqian WANG, Guixia PAN, Guorong JIA, Xiao LI, Chao WANG, Liming ZHANG, Changjing ZUO
Physiol Res. 2023 Feb; 72(1): 49–57. Published online 2022 Dec 22. doi: 10.33549/physiolres.934950
PMCID:
PMC10069816
AbstractArticlePDF–1.1M
4.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
5.
ASIC1a stimulates the resistance of human hepatocellular carcinoma by promoting EMT via the AKT/GSK3β/Snail pathway driven by TGFβ/Smad signals
Yinci Zhang, Niandie Cao, Jiafeng Gao, Jiaojiao Liang, Yong Liang, Yinghai Xie, Shuping Zhou, Xiaolong Tang
J Cell Mol Med. 2022 May; 26(10): 2777–2792. Published online 2022 Apr 14. doi: 10.1111/jcmm.17288
PMCID:
PMC9097844
AbstractArticlePDF–54M
6.
Upregulation of acid sensing ion channels is associated with esophageal hypersensitivity in GERD
Xu Han, Yawen Zhang, Allen Lee, Zhaoshen Li, Jun Gao, Xiaoyin Wu, Jiulong Zhao, Hui Wang, Di Chen, Duowu Zou, Chung Owyang
FASEB J. 2022 Jan; 36(1): e22083. Published online 2021 Dec 17. doi: 10.1096/fj.202100606R
PMCID:
PMC8715981
AbstractArticlePDF–1.6M
7.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
8.
Regulation of gliomagenesis and stemness through acid sensor ASIC1a
Pendelton King, Jingwei Wan, Alyssa Aihui Guo, Shanchun Guo, Yugang Jiang, Mingli Liu
Int J Oncol. 2021 Oct; 59(4): 82. Published online 2021 Sep 10. doi: 10.3892/ijo.2021.5262
PMCID:
PMC8448544
AbstractArticlePDF–2.4M
9.
Structure and analysis of nanobody binding to the human ASIC1a ion channel
Yangyu Wu, Zhuyuan Chen, Fred J Sigworth, Cecilia M Canessa
eLife. 2021; 10: e67115. Published online 2021 Jul 28. doi: 10.7554/eLife.67115
PMCID:
PMC8318589
AbstractArticlePDF–5.7M
10.
Expression Profiles of ASIC1/2 and TRPV1/4 in Common Skin Tumors
Kirsten Ackermann, Susanne Wallner, Christoph Brochhausen, Stephan Schreml
Int J Mol Sci. 2021 Jun; 22(11): 6024. Published online 2021 Jun 2. doi: 10.3390/ijms22116024
PMCID:
PMC8199644
AbstractArticlePDF–68M
11.
Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1
Matthew L. Rook, Megan Miaro, Tyler Couch, Dana L. Kneisley, Maria Musgaard, David M. MacLean
J Gen Physiol. 2021 Aug 2; 153(8): e202012855. Published online 2021 Jun 1. doi: 10.1085/jgp.202012855
PMCID:
PMC8167889
AbstractArticlePDF–3.2M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration
Jingyu Ding, Renjie Zhang, Huimin Li, Qiang Ji, Xiaomin Cheng, Rick Francis Thorne, Hubert Hondermarck, Xiaoying Liu, Cailiang Shen
Aging (Albany NY) 2021 Apr 15; 13(7): 10703–10723. Published online 2021 Apr 6. doi: 10.18632/aging.202850
PMCID:
PMC8064223
AbstractArticlePDF–2.0M
14.
Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate
Sabrina Vullo, Nicolas Ambrosio, Jan P Kucera, Olivier Bignucolo, Stephan Kellenberger
eLife. 2021; 10: e66488. Published online 2021 Mar 17. doi: 10.7554/eLife.66488
PMCID:
PMC8009679
AbstractArticlePDF–6.0M
15.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
16.
Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Target for Rheumatoid Arthritis
Yayun Xu, Feihu Chen
Front Immunol. 2020; 11: 580936. Published online 2021 Jan 28. doi: 10.3389/fimmu.2020.580936
PMCID:
PMC7876322
AbstractArticlePDF–937K
17.
Postsynaptic Targeting and Mobility of Membrane Surface-Localized hASIC1a
Xing-Lei Song, Di-Shi Liu, Min Qiang, Qian Li, Ming-Gang Liu, Wei-Guang Li, Xin Qi, Nan-Jie Xu, Guang Yang, Michael Xi Zhu, Tian-Le Xu
Neurosci Bull. 2021 Feb; 37(2): 145–165. Published online 2020 Sep 30. doi: 10.1007/s12264-020-00581-9
PMCID:
PMC7870742
AbstractArticlePDF–4.6M
18.
Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1
Demeng Sun, Sanling Liu, Siyu Li, Mengge Zhang, Fan Yang, Ming Wen, Pan Shi, Tao Wang, Man Pan, Shenghai Chang, Xing Zhang, Longhua Zhang, Changlin Tian, Lei Liu
eLife. 2020; 9: e57096. Published online 2020 Sep 11. doi: 10.7554/eLife.57096
PMCID:
PMC7553779
AbstractArticlePDF–3.1M
19.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
20.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M

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