PMC Links for GEO Profiles (Select 98964770) - PMC

Result Filters

Links from GEO Profiles

Items: 1 to 20 of 117

<< First< Prev

Page of 6

Next >Last >>

Select item 111151161.

Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278)

Yenny Y. Acosta, Maria Paz Zafra, Gloria Ojeda, Ilaria Seren Bernardone, Umberto Dianzani, Pilar Portolés, Jose M. Rojo

Cell Mol Life Sci. 2011 Sep; 68(18): 3065–3079. Published online 2010 Dec 28. doi: 10.1007/s00018-010-0606-1

PMCID:: PMC11115116

Abstract Article PDF–743K

Select item 107703462.

A combined opposite targeting of p110δ PI3K and RhoA abrogates skin cancer

Niki Tzenaki, Lydia Xenou, Evangelia Goulielmaki, Anna Tsapara, Irene Voudouri, Angelika Antoniou, George Valianatos, Maria Tzardi, Eelco De Bree, Aikaterini Berdiaki, Antonios Makrigiannakis, Evangelia A. Papakonstanti

Commun Biol. 2024; 7: 26. Published online 2024 Jan 5. doi: 10.1038/s42003-023-05639-8

PMCID:: PMC10770346

Abstract Article PDF–3.2M

Select item 100373413.

Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2

Tina Nguyen, Anthony Lau, Julia Bier, Kristen C. Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T. Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S. Abraham, Nipunie Rajapakse, Eric W. Klee, Joseph A. Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R. Croucher, David E. James, Cindy S. Ma, Robert Brink, Stuart G. Tangye, Elissa K. Deenick

J Exp Med. 2023 Jun 5; 220(6): e20221020. Published online 2023 Mar 21. doi: 10.1084/jem.20221020

PMCID:: PMC10037341

Abstract Article PDF–6.2M

Select item 99463504.

PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells

Kristina Ames, Imit Kaur, Yang Shi, Meng M. Tong, Taneisha Sinclair, Shayda Hemmati, Shira G. Glushakow-Smith, Ellen Tein, Lindsay Gurska, Ulrich Steidl, Robert Dubin, Jidong Shan, Cristina Montagna, Kith Pradhan, Amit Verma, Kira Gritsman

Sci Adv. 2023 Feb; 9(8): eade8222. Published online 2023 Feb 22. doi: 10.1126/sciadv.ade8222

PMCID:: PMC9946350

Abstract Article PDF–2.4M

Select item 96270445.

DOCK2 and phosphoinositide-3 kinase δ mediate two complementary signaling pathways for CXCR5-dependent B cell migration

Stefanie Wissmann, Bettina Stolp, Ana Marcos Jímenez, Jens V. Stein

Front Immunol. 2022; 13: 982383. Published online 2022 Oct 19. doi: 10.3389/fimmu.2022.982383

PMCID:: PMC9627044

Abstract Article PDF–4.0M

Select item 94407566.

TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells

Jessica W. Bertol, Shelby Johnston, Rabia Ahmed, Victoria K. Xie, Kelsea M. Hubka, Lissette Cruz, Larissa Nitschke, Marta Stetsiv, Jeremy P. Goering, Paul Nistor, Sally Lowell, Hanne Hoskens, Peter Claes, Seth M. Weinberg, Irfan Saadi, Mary C. Farach-Carson, Walid D. Fakhouri

Development. 2022 Aug 1; 149(15): dev200068. Published online 2022 Aug 8. doi: 10.1242/dev.200068

PMCID:: PMC9440756

Abstract Article

Select item 92238487.

Lack of Functional P110δ Affects Expression of Activation Marker CD80 but Does Not Influence Functions of Neutrophils

Aneta Manda-Handzlik, Agnieszka Mroczek, Weronika Kuźmicka, Adrianna Cieloch, Zuzanna Homoncik, Angelika Muchowicz, Urszula Demkow, Małgorzata Wachowska

Int J Mol Sci. 2022 Jun; 23(12): 6361. Published online 2022 Jun 7. doi: 10.3390/ijms23126361

PMCID:: PMC9223848

Abstract Article PDF–2.2M

Select item 86140198.

PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway

Zhenzhu Liu, Jing Li, Shu Lin, Yuhang Wu, Dan He, Peng Qu

Exp Anim. 2021; 70(4): 488–497. Published online 2021 Jun 22. doi: 10.1538/expanim.21-0002

PMCID:: PMC8614019

Abstract Article PDF–2.9M

Select item 85820809.

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8⁺ T cells at the expense of central memory

Jennifer L. Cannons, Alejandro V. Villarino, Senta M. Kapnick, Silvia Preite, Han-Yu Shih, Julio Gomez-Rodriguez, Zenia Kaul, Hirofumi Shibata, Julie M. Reilley, Bonnie Huang, Robin Handon, Ian T. McBain, Selamawit Gossa, Tuoqi Wu, Helen C. Su, Dorian B. McGavern, John J. O’Shea, Peter J. McGuire, Gulbu Uzel, Pamela L. Schwartzberg

Cell Rep. Author manuscript; available in PMC 2021 Nov 11.

Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109804. doi: 10.1016/j.celrep.2021.109804

PMCID:: PMC8582080

Abstract Article PDF–3.2M

Select item 848585610.

Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing ER stress

Fahd Al Qureshah, Sara Sagadiev, Christopher D. Thouvenel, Shuozhi Liu, Zhaolin Hua, Baidong Hou, Mridu Acharya, Richard G. James, David J. Rawlings

J Exp Med. 2021 Dec 6; 218(12): e20211035. Published online 2021 Sep 29. doi: 10.1084/jem.20211035

PMCID:: PMC8485856

Abstract Article PDF–5.5M

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 825042212.

Phosphoinositide 3-Kinase p110 Delta Differentially Restrains and Directs Naïve Versus Effector CD8⁺ T Cell Transcriptional Programs

Laura Spinelli, Julia M. Marchingo, Aneela Nomura, Marcos P. Damasio, Doreen A. Cantrell

Front Immunol. 2021; 12: 691997. Published online 2021 Jun 18. doi: 10.3389/fimmu.2021.691997

PMCID:: PMC8250422

Abstract Article PDF–5.8M

Select item 798242313.

PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4⁺ T Cells

Daisy H. Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug

Front Immunol. 2021; 12: 631271. Published online 2021 Mar 8. doi: 10.3389/fimmu.2021.631271

PMCID:: PMC7982423

Abstract Article PDF–2.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 772681415.

Class IA PI3Ks regulate subcellular and functional dynamics of IDO1

Alberta Iacono, Andrea Pompa, Francesca De Marchis, Eleonora Panfili, Francesco A Greco, Alice Coletti, Ciriana Orabona, Claudia Volpi, Maria L Belladonna, Giada Mondanelli, Elisa Albini, Carmine Vacca, Marco Gargaro, Francesca Fallarino, Roberta Bianchi, Carine De Marcos Lousa, Emilia MC Mazza, Silvio Bicciato, Elisa Proietti, Francesca Milano, Maria P Martelli, Ioana M Iamandii, Mariona Graupera Garcia‐Mila, Judith Llena Sopena, Phillip Hawkins, Sabine Suire, Klaus Okkenhaug, Anne‐Katrien Stark, Fabio Grassi, Michele Bellucci, Paolo Puccetti, Laura Santambrogio, Antonio Macchiarulo, Ursula Grohmann, Maria T Pallotta

EMBO Rep. 2020 Dec 3; 21(12): e49756. Published online 2020 Nov 7. doi: 10.15252/embr.201949756

PMCID:: PMC7726814

Abstract Article PDF–5.6M

Select item 753345916.

Deletion of P110δ promotes the development of myocarditis in ApoE-deficient mice by increasing mononuclear cell peritoneal infiltration

Qi-Zhi Zhang, Ai-Ying Xue, Wei Wei, Ai-Min Pang, Li-Na Cao, Fang Liu

Mol Med Rep. 2020 Nov; 22(5): 3629–3634. Published online 2020 Aug 21. doi: 10.3892/mmr.2020.11451

PMCID:: PMC7533459

Abstract Article PDF–443K

Select item 734386817.

Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate

Jack A. Bibby, Harriet A. Purvis, Thomas Hayday, Anita Chandra, Klaus Okkenhaug, Sofia Rosenzweig, Ivona Aksentijevich, Michael Wood, Helen J. Lachmann, Claudia Kemper, Andrew P. Cope, Esperanza Perucha

Nat Commun. 2020; 11: 3412. Published online 2020 Jul 8. doi: 10.1038/s41467-020-17179-4

PMCID:: PMC7343868

Abstract Article PDF–2.6M

Select item 731120118.

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

Anne-Katrien Stark, Elizabeth C. M. Davenport, Daniel T. Patton, Cheryl L. Scudamore, Bart Vanhaesebroeck, Marc Veldhoen, Oliver A. Garden, Klaus Okkenhaug

J Immunol. 2020 Jul 1; 205(1): 78–89. Published online 2020 May 15. doi: 10.4049/jimmunol.2000043

PMCID:: PMC7311201

Abstract Article PDF–1.8M

Select item 708524819.

PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis

Wenyi Wu, Guohong Zhou, Haote Han, Xionggao Huang, Heng Jiang, Shizuo Mukai, Andrius Kazlauskas, Jing Cui, Joanne Aiko Matsubara, Bart Vanhaesebroeck, Xiaobo Xia, Jiantao Wang, Hetian Lei

Diabetes. 2020 Apr; 69(4): 736–748. Published online 2020 Jan 8. doi: 10.2337/db19-0713

PMCID:: PMC7085248

Abstract Article PDF–2.4M

Select item 704171220.

Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production

Anthony Lau, Danielle T. Avery, Katherine Jackson, Helen Lenthall, Stefano Volpi, Henry Brigden, Amanda J. Russell, Julia Bier, Joanne H. Reed, Joanne M. Smart, Theresa Cole, Sharon Choo, Paul E. Gray, Lucinda J. Berglund, Peter Hsu, Melanie Wong, Michael O’Sullivan, Kaan Boztug, Isabelle Meyts, Gulbu Uzel, Luigi D. Notarangelo, Robert Brink, Christopher C. Goodnow, Stuart G. Tangye, Elissa K. Deenick

J Exp Med. 2020 Feb 3; 217(2): e20191336. Published online 2019 Dec 16. doi: 10.1084/jem.20191336

PMCID:: PMC7041712

Abstract Article PDF–5.0M

<< First< Prev

Page of 6

Next >Last >>

Supplemental Content

Filter your results:

Manage Filters

Find related data

Recent activity

Clear Turn Off Turn On

PMC Links for GEO Profiles (Select 98964770) (117)
PMC
dbVar for Gene (Select 149951) (490)
dbVar
laforin isoform X1 [Rattus norvegicus]
laforin isoform X1 [Rattus norvegicus]
gi|1958641528|ref|XP_038962147.1|

Protein
COMM domain-containing protein 7 isoform X5 [Homo sapiens]
COMM domain-containing protein 7 isoform X5 [Homo sapiens]
gi|2462579625|ref|XP_054179059.1|

Protein
PREDICTED: Homo sapiens COMM domain containing 7 (COMMD7), transcript variant X5...
PREDICTED: Homo sapiens COMM domain containing 7 (COMMD7), transcript variant X5, mRNA
gi|2462579624|ref|XM_054323084.1|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to: