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Items: 1 to 20 of 403

1.
Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps
Seyedeh Nasim Mirbahari, Nayeralsadat Fatemi, Sanaz Savabkar, Vahid Chaleshi, Neda Zali, Mohammad Yaghoob Taleghani, Ebrahim Mirzaei, Leili Rejali, Pardis Ketabi Moghadam, Ehsan Nazemalhosseini Mojarad
Mol Biol Rep. 2024; 51(1): 764. Published online 2024 Jun 14. doi: 10.1007/s11033-024-09683-3
PMCID:
PMC11178608
AbstractArticlePDF–2.9M
2.
Molecular epidemiological and mutational analysis of DNA mismatch repair (MMR) genes in endometrial cancer patients with HNPCC‐associated familial predisposition to cancer
Y. Hirai, K. Banno, M. Suzuki, Y. Ichikawa, Y. Udagawa, K. Sugano, Y. Miki
Cancer Sci. 2008 Sep; 99(9): 1715–1719. Published online 2008 Jul 9. doi: 10.1111/j.1349-7006.2008.00886.x
PMCID:
PMC11159862
AbstractArticlePDF–128K
3.
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer
Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park
Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x
PMCID:
PMC11159840
AbstractArticlePDF–209K
4.
Frequent alterations of the candidate genes hMLH1, ITGA9 and RBSP3 in early dysplastic lesions of head and neck: Clinical and prognostic significance
Amlan Ghosh, Susmita Ghosh, Guru Prasad Maiti, Mohammad Golam Sabbir, Eugene R. Zabarovsky, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda
Cancer Sci. 2010 Jun; 101(6): 1511–1520. Published online 2010 Mar 4. doi: 10.1111/j.1349-7006.2010.01551.x
PMCID:
PMC11159363
AbstractArticlePDF–891K
5.
Frequent alterations of hMLH1 and RBSP3/HYA22 at chromosomal 3p22.3 region in early and late‐onset breast carcinoma: clinical and prognostic significance
Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda
Cancer Sci. 2008 Oct; 99(10): 1984–1991. Published online 2008 Oct 14. doi: 10.1111/j.1349-7006.2008.00952.x
PMCID:
PMC11158254
AbstractArticlePDF–609K
6.
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner
Vincent E. Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L. Hegde
Mol Brain. 2024; 17: 32. Published online 2024 Jun 5. doi: 10.1186/s13041-024-01108-3
PMCID:
PMC11155029
AbstractArticlePDF–1.7M
7.
Histone H3K9 Lactylation Confers Temozolomide Resistance in Glioblastoma via LUC7L2‐Mediated MLH1 Intron Retention
Qu Yue, Zhao Wang, Yixiong Shen, Yufei Lan, Xiangyang Zhong, Xin Luo, Tao Yang, Manqing Zhang, Boming Zuo, Tianci Zeng, Jiankun Lu, Yuankai Wang, Boyang Liu, Hongbo Guo
Adv Sci (Weinh) 2024 May; 11(19): 2309290. Published online 2024 Mar 13. doi: 10.1002/advs.202309290
PMCID:
PMC11109612
AbstractArticlePDF–15M
8.
Loss of mutL homolog-1 (MLH1) expression promotes acquisition of oncogenic and inhibitor-resistant point mutations in tyrosine kinases
Lorraine Springuel, Elisabeth Losdyck, Pascale Saussoy, Béatrice Turcq, François-Xavier Mahon, Laurent Knoops, Jean-Christophe Renauld
Cell Mol Life Sci. 2016 Dec; 73(24): 4739–4748. Published online 2016 Jul 19. doi: 10.1007/s00018-016-2310-2
PMCID:
PMC11108519
AbstractArticlePDF–1.2M
9.
Variable Expression of MSH6 in Endometrial Carcinomas with Intact Mismatch Repair and with MLH1 Loss due to MLH1 Methylation
Nidhi Tandon, Courtney Hudgens, Bryan Fellman, Michael T. Tetzlaff, Russell R. Broaddus
Int J Gynecol Pathol. Author manuscript; available in PMC 2024 Jan 29.
Published in final edited form as: Int J Gynecol Pathol. 2020 Nov; 39(6): 507–513. doi: 10.1097/PGP.0000000000000655
PMCID:
PMC10824249
AbstractArticlePDF–1.8M
10.
Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome
Seyed Mohsen Mirabdolhosseini, Mohammad Yaghoob Taleghani, Leili Rejali, Hossein Sadeghi, Nayeralsadat Fatemi, Mehdi Tavallaei, Amin Famil Meyari, Narges Saeidi, Pardis Ketabi Moghadam, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Ehsan Nazemalhosseini Mojarad
Cancer Rep (Hoboken) 2024 Jan; 7(1): e1930. Published online 2023 Nov 2. doi: 10.1002/cnr2.1930
PMCID:
PMC10809271
AbstractArticlePDF–4.7M
11.
MLH1 rs1800734 Pathogenic Variant among Patients with Colorectal Cancer in the Lower Northeastern Region of Thailand
Malinee Pongsavee, Kamol Wisuwan, Kritpipat Pongsavee
Asian Pac J Cancer Prev. 2023; 24(8): 2911–2916. doi: 10.31557/APJCP.2023.24.8.2911
PMCID:
PMC10685219
AbstractArticlePDF–390K
12.
MLH1 Promoter Methylation Could Be the Second Hit in Lynch Syndrome Carcinogenesis
Ileana Wanda Carnevali, Giulia Cini, Laura Libera, Nora Sahnane, Sofia Facchi, Alessandra Viel, Fausto Sessa, Maria Grazia Tibiletti
Genes (Basel) 2023 Nov; 14(11): 2060. Published online 2023 Nov 9. doi: 10.3390/genes14112060
PMCID:
PMC10670941
AbstractArticlePDF–1.5M
13.
Both MLH1 deficiency and BRAFV600E mutation are a unique characteristic of colorectal medullary carcinoma: An observational study
Masanao Kaneko, Mitsuko Nakashima, Kiichi Sugiura, Natsuki Ishida, Satoshi Tamura, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Satoshi Osawa, Kyota Tatsuta, Kiyotaka Kurachi, Satoshi Baba, Yuji Iwashita, Tomio Arai, Haruhiko Sugimura, Masato Maekawa, Ken Sugimoto, Moriya Iwaizumi
Medicine (Baltimore) 2023 Sep 22; 102(38): e35022. Published online 2023 Sep 22. doi: 10.1097/MD.0000000000035022
PMCID:
PMC10519469
AbstractArticlePDF–708K
14.
Prevalence of Somatic MutL Homolog 1 Promoter Hypermethylation in Lynch Syndrome Colorectal Cancer
Leticia Moreira, Jenifer Muñoz, Míriam Cuatrecasas, Isabel Quintanilla, Maria Liz Leoz, Sabela Carballal, Teresa Ocaña, María López-Cerón, Maria Pellise, Sergi Castellví-Bel, Rodrigo Jover, Montserrat Andreu, Angel Carracedo, Rosa Maria Xicola, Xavier Llor, Clement Richard Boland, Ajay Goel, Antoni Castells, Francesc Balaguer, Gastrointestinal Oncology Group of the Spanish Gastroenterological Association
Cancer. Author manuscript; available in PMC 2023 Sep 19.
Published in final edited form as: Cancer. 2015 May 1; 121(9): 1395–1404. Published online 2014 Dec 29. doi: 10.1002/cncr.29190
PMCID:
PMC10508888
AbstractArticlePDF–418K
15.
Key role of phosphorylation sites in ATPase domain and Linker region of MLH1 for DNA binding and functionality of MutLα
May-Britt Firnau, Guido Plotz, Stefan Zeuzem, Angela Brieger
Sci Rep. 2023; 13: 12503. Published online 2023 Aug 2. doi: 10.1038/s41598-023-39750-x
PMCID:
PMC10397344
AbstractArticlePDF–1.7M
16.
A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation
Karla Wolf, Jan Kosinski, Toby J Gibson, Nicole Wesch, Volker Dötsch, Maurizio Genuardi, Emanuela Lucci Cordisco, Stefan Zeuzem, Angela Brieger, Guido Plotz
Nucleic Acids Res. 2023 Jul 7; 51(12): 6307–6320. Published online 2023 May 24. doi: 10.1093/nar/gkad418
PMCID:
PMC10325900
AbstractArticlePDF–1.7M
17.
MLH1 Loss in Primary Prostate Cancer
Sanaz Nourmohammadi Abadchi, Laura A. Sena, Emmanuel S. Antonarakis, Colin C. Pritchard, James R. Eshleman, Eric Q. Konnick, Stephen J. Salipante, Eugene Shenderov, Tamara L. Lotan
JCO Precis Oncol. 2023; 7: e2200611. Published online 2023 May 17. doi: 10.1200/PO.22.00611
PMCID:
PMC10309570
AbstractArticlePDF–899K
18.
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
PMCID:
PMC10284117
AbstractArticlePDF–2.5M
19.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
20.
The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA
Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay
J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027
PMCID:
PMC10005898
AbstractArticlePDF–6.7M

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