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Select item 110735071.

DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms

Theadora Vessella, Steven Xiang, Cong Xiao, Madelyn Stilwell, Jaidyn Fok, Jason Shohet, Esteban Rozen, H. Susan Zhou, Qi Wen

FEBS Open Bio. 2024 May; 14(5): 867–882. Published online 2024 Mar 27. doi: 10.1002/2211-5463.13798

PMCID:: PMC11073507

Abstract Article PDF–1.9M

Select item 109168662.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 107867133.

DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression

Favour A. Akinjiyan, Zainab Ibitoye, Peinan Zhao, Leah P. Shriver, Gary J. Patti, Gregory D. Longmore, Katherine C. Fuh

Oncogene. 2024; 43(3): 189–201. Published online 2023 Nov 23. doi: 10.1038/s41388-023-02884-3

PMCID:: PMC10786713

Abstract Article PDF–4.1M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729065.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98816456.

DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1

Allison V. Mitchell, Jason Wu, Fanyan Meng, Lun Dong, C. James Block, Won-min Song, Bin Zhang, Jing Li, Guojun Wu

Cancer Res Commun. 2022 Nov; 2(11): 1388–1403. Published online 2022 Nov 9. doi: 10.1158/2767-9764.CRC-22-0013

PMCID:: PMC9881645

Abstract Article PDF–9.8M

Select item 91872917.

Discoidin Domain Receptor 2 Expression as Worse Prognostic Marker in Invasive Breast Cancer

Irene Romayor, Marina Luque García-Vaquero, Joana Márquez, Beatriz Arteta, Ramón Barceló, Aitor Benedicto

Breast J. 2022; 2022: 5169405. Published online 2022 Mar 7. doi: 10.1155/2022/5169405

PMCID:: PMC9187291

Abstract Article PDF–12M

Select item 91714118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 85423849.

Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis

Craig E. Barcus, Priscilla Y. Hwang, Vasilios Morikis, Audrey Brenot, Patrick Pence, Maria Clarke, Gregory D. Longmore

J Cell Sci. 2021 Oct 1; 134(19): jcs258431. Published online 2021 Oct 13. doi: 10.1242/jcs.258431

PMCID:: PMC8542384

Abstract Article

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 816085711.

Discoidin Domain Receptor 2 Mediates Lysophosphatidic Acid-Induced Ovarian Cancer Aggressiveness

Bo Young Jeong, Kyung Hwa Cho, Se-Hee Yoon, Chang Gyo Park, Hwan-Woo Park, Hoi Young Lee

Int J Mol Sci. 2021 May; 22(10): 5374. Published online 2021 May 20. doi: 10.3390/ijms22105374

PMCID:: PMC8160857

Abstract Article PDF–10M

Select item 798830812.

DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

Chao-Chieh Lin, Wen-Hsuan Yang, Yi-Tzu Lin, Xiaohu Tang, Po-Han Chen, Chien-Kuang Cornelia Ding, Dan Chen Qu, James V. Alvarez, Jen-Tsan Chi

Oncogene. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Oncogene. 2021 Mar; 40(11): 2018–2034. Published online 2021 Feb 18. doi: 10.1038/s41388-021-01676-x

PMCID:: PMC7988308

Abstract Article PDF–2.4M

Select item 701284413.

Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts

Benjamin Wasinski, Anjum Sohail, R. Daniel Bonfil, Seongho Kim, Allen Saliganan, Lisa Polin, Mohamad Bouhamdan, Hyeong-Reh C. Kim, Marco Prunotto, Rafael Fridman

Sci Rep. 2020; 10: 2309. Published online 2020 Feb 11. doi: 10.1038/s41598-020-59028-w

PMCID:: PMC7012844

Abstract Article PDF–2.2M

Select item 685134014.

Heat shock protein 47 (HSP47) binds to discoidin domain–containing receptor 2 (DDR2) and regulates its protein stability

Jie Chen, Shike Wang, Zhihui Zhang, Christopher I. Richards, Ren Xu

J Biol Chem. 2019 Nov 8; 294(45): 16846–16854. Published online 2019 Sep 30. doi: 10.1074/jbc.RA119.009312

PMCID:: PMC6851340

Abstract Article PDF–2.1M

Select item 652815815.

An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations

Keran Jiang, Zhongli Yang, Wenyan Cui, Kunkai Su, Jennie Z Ma, Thomas J Payne, Ming D Li

Nicotine Tob Res. 2019 Jun; 21(6): 707–713. Published online 2017 Dec 5. doi: 10.1093/ntr/ntx262

PMCID:: PMC6528158

Abstract Article PDF–3.6M

Select item 636303416.

DDR1 and DDR2 physical interaction leads to signaling interconnection but with possible distinct functions

Coralie Croissant, Adjanie Tuariihionoa, Marion Bacou, Wilfried Souleyreau, Margaux Sala, Elodie Henriet, Andreas Bikfalvi, Frederic Saltel, Patrick Auguste

Cell Adh Migr. 2018; 12(4): 324–334. Published online 2018 Jun 25. doi: 10.1080/19336918.2018.1460012

PMCID:: PMC6363034

Abstract Article PDF–1.6M

Select item 628805017.

Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome

Linda Xu, Hanne Jensen, Jennifer J. Johnston, Emilio Di Maria, Katja Kloth, Ileana Cristea, Julie C. Sapp, Thomas N. Darling, Laryssa A. Huryn, Lisbeth Tranebjærg, Elisa Cinotti, Christian Kubisch, Eyvind Rødahl, Ove Bruland, Leslie G. Biesecker, Gunnar Houge, Cecilie Bredrup

Am J Hum Genet. 2018 Dec 6; 103(6): 976–983. Published online 2018 Nov 15. doi: 10.1016/j.ajhg.2018.10.013