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Select item 108046151.

Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells

Alexander Calderon, Tamara Mestvirishvili, Francesco Boccalatte, Kelly V. Ruggles, Gregory David

Epigenetics Chromatin. 2024; 17: 2. Published online 2024 Jan 23. doi: 10.1186/s13072-024-00526-w

PMCID:: PMC10804615

Abstract Article PDF–4.5M

Select item 79689252.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Abstract Article PDF–4.0M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72432924.

Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca²⁺ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

Xiaodun Yang, Sarah M. Graff, Cody N. Heiser, Kung-Hsien Ho, Bob Chen, Alan J. Simmons, Austin N. Southard-Smith, Gregory David, David A. Jacobson, Irina Kaverina, Christopher V.E. Wright, Ken S. Lau, Guoqiang Gu

Diabetes. 2020 Jun; 69(6): 1219–1231. Published online 2020 Apr 3. doi: 10.2337/db19-0721

PMCID:: PMC7243292

Abstract Article PDF–2.7M

Select item 69939255.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 66927706.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 61971547.

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function

Fanny Langlet, Marcel Tarbier, Rebecca A. Haeusler, Stefania Camastra, Eleuterio Ferrannini, Marc R. Friedländer, Domenico Accili

Mol Metab. 2018 Nov; 17: 49–60. Published online 2018 Aug 11. doi: 10.1016/j.molmet.2018.08.003

PMCID:: PMC6197154

Abstract Article PDF–2.3M

Select item 61370958.

Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities

Jun-ichi Kurita, Yuuka Hirao, Hirofumi Nakano, Yoshifumi Fukunishi, Yoshifumi Nishimura

Sci Rep. 2018; 8: 13763. Published online 2018 Sep 13. doi: 10.1038/s41598-018-31852-1

PMCID:: PMC6137095

Abstract Article PDF–4.5M

Select item 56878499.

Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

Fanny Langlet, Rebecca A. Haeusler, Daniel Lindén, Elke Ericson, Tyrrell Norris, Anders Johansson, Joshua R. Cook, Kumiko Aizawa, Ling Wang, Christoph Buettner, Domenico Accili

Cell. Author manuscript; available in PMC 2018 Nov 2.

Published in final edited form as: Cell. 2017 Nov 2; 171(4): 824–835.e18. Published online 2017 Oct 19. doi: 10.1016/j.cell.2017.09.045

PMCID:: PMC5687849

Abstract Article PDF–2.5M

Select item 564508210.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 562663111.

Chromatin-associated protein SIN3B prevents prostate cancer progression by inducing senescence

Anthony J. Bainor, Fang-Ming Deng, Yu Wang, Peng Lee, David J. Cantor, Susan K. Logan, Gregory David

Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5339–5348. Published online 2017 Aug 14. doi: 10.1158/0008-5472.CAN-16-3410

PMCID:: PMC5626631

Abstract Article PDF–2.5M

Select item 553876912.

Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal

Gundula Streubel, Darren J Fitzpatrick, Giorgio Oliviero, Andrea Scelfo, Bruce Moran, Sudipto Das, Nayla Munawar, Ariane Watson, Kieran Wynne, Gian Luca Negri, Eugene T Dillon, SriGanesh Jammula, Karsten Hokamp, Darran P O'Connor, Diego Pasini, Gerard Cagney, Adrian P Bracken

EMBO J. 2017 Aug 1; 36(15): 2216–2232. Published online 2017 May 29. doi: 10.15252/embj.201696307

PMCID:: PMC5538769

Abstract Article PDF–1.1M

Select item 553692913.

Sin3a regulates epithelial progenitor cell fate during lung development

Changfu Yao, Gianni Carraro, Bindu Konda, Xiangrong Guan, Takako Mizuno, Norika Chiba, Matthew Kostelny, Adrianne Kurkciyan, Gregory David, Jonathan L. McQualter, Barry R. Stripp

Development. 2017 Jul 15; 144(14): 2618–2628. doi: 10.1242/dev.149708

PMCID:: PMC5536929

Abstract Article

Select item 521626514.

The chromatin-associated Sin3B protein is required for hematopoietic stem cell functions in mice

David J. Cantor, Gregory David

Blood. 2017 Jan 5; 129(1): 60–70. Prepublished online 2016 Nov 2. doi: 10.1182/blood-2016-06-721746

PMCID:: PMC5216265

Abstract Article

Select item 491493115.

Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39

Noel Faherty, Matthew Benson, Eshita Sharma, Angela Lee, Alison Howarth, Helen Lockstone, Daniel Ebner, Shoumo Bhattacharya

Sci Rep. 2016; 6: 28210. Published online 2016 Jun 21. doi: 10.1038/srep28210

PMCID:: PMC4914931

Abstract Article PDF–1.5M

Select item 449466216.

Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors

Xiaozhong Shi, David C. Seldin, Daniel J. Garry

Biochem J. Author manuscript; available in PMC 2015 Jul 7.

Published in final edited form as: Biochem J. 2012 Sep 15; 446(3): 349–357. doi: 10.1042/BJ20120563

PMCID:: PMC4494662

Abstract Article PDF–1.1M

Select item 449465117.

Sin3 interacts with Foxk1 and regulates myogenic progenitors

Xiaozhong Shi, Daniel J. Garry

Mol Cell Biochem. Author manuscript; available in PMC 2015 Jul 7.

Published in final edited form as: Mol Cell Biochem. 2012 Jul; 366(0): 251–258. Published online 2012 Apr 4. doi: 10.1007/s11010-012-1302-2

PMCID:: PMC4494651

Abstract Article PDF–923K

Select item 437731418.

Transcriptional repression of Sin3B by Bmi-1 prevents cellular senescence and is relieved by oncogene activation

Teresa DiMauro, David J. Cantor, Anthony J. Bainor, Gregory David

Oncogene. Author manuscript; available in PMC 2016 Jan 23.

Published in final edited form as: Oncogene. 2015 Jul 23; 34(30): 4011–4017. Published online 2014 Sep 29. doi: 10.1038/onc.2014.322

PMCID:: PMC4377314

Abstract Article PDF–1.2M

Select item 413923419.

Sin3b Interacts with Myc and Decreases Myc Levels

Pablo Garcia-Sanz, Andrea Quintanilla, M. Carmen Lafita, Gema Moreno-Bueno, Lucia García-Gutierrez, Vedrana Tabor, Ignacio Varela, Yuzuru Shiio, Lars-Gunnar Larsson, Francisco Portillo, Javier Leon

J Biol Chem. 2014 Aug 8; 289(32): 22221–22236. Published online 2014 Jun 20. doi: 10.1074/jbc.M113.538744

PMCID:: PMC4139234

Abstract Article PDF–3.1M

Select item 400154820.

Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression

Maïté Rielland, David J. Cantor, Richard Graveline, Cristina Hajdu, Lisa Mara, Beatriz de Diego Diaz, George Miller, Gregory David

J Clin Invest. 2014 May 1; 124(5): 2125–2135. Published online 2014 Apr 1. doi: 10.1172/JCI72619

PMCID:: PMC4001548

Abstract Article PDF–7.1M

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