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Select item 112871781.

Diabetic Macrophage Exosomal miR-381-3p Inhibits Epithelial Cell Autophagy Via NR5A2

Xin Huang, Linhesheng Wei, Mengdi Li, Yong Zhang, Shuhong Kuang, Zongshan Shen, Hui Liu, Zhengmei Lin

Int Dent J. 2024 Aug; 74(4): 823–835. Published online 2024 Apr 28. doi: 10.1016/j.identj.2024.02.001

PMCID:: PMC11287178

Abstract Article PDF–615K

Select item 111145382.

Identification of two functional nuclear localization signals mediating nuclear import of liver receptor homologue-1

Feng-Ming Yang, Yu-Chi Lin, Meng-Chun Hu

Cell Mol Life Sci. 2011 Apr; 68(7): 1241–1253. Published online 2010 Sep 19. doi: 10.1007/s00018-010-0521-5

PMCID:: PMC11114538

Abstract Article PDF–897K

Select item 108779273.

Embryonic temporal–spatial delineation of excitatory spinal V3 interneuron diversity

Dylan Deska-Gauthier, Joanna Borowska-Fielding, Chris Jones, Han Zhang, Colin S. MacKay, Ramez Michail, Laura A. Bennett, Jay B. Bikoff, Ying Zhang

Cell Rep. Author manuscript; available in PMC 2024 Feb 20.

Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113635. Published online 2023 Dec 29. doi: 10.1016/j.celrep.2023.113635

PMCID:: PMC10877927

Abstract Article PDF–2.8M

Select item 107093094.

NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos

Fangnong Lai, Lijia Li, Xiaoyu Hu, Bofeng Liu, Ziqi Zhu, Ling Liu, Qiang Fan, Huabin Tian, Kai Xu, Xukun Lu, Qing Li, Kong Feng, Lijuan Wang, Zili Lin, Hongyu Deng, Jinsong Li, Wei Xie

Cell Res. 2023 Dec; 33(12): 952–966. Published online 2023 Nov 7. doi: 10.1038/s41422-023-00887-z

PMCID:: PMC10709309

Abstract Article PDF–2.5M

Select item 106884785.

Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1

Madeleine Birgersson, Rajitha Indukuri, Linnéa Lindquist, Lina Stepanauskaite, Qing Luo, Qiaolin Deng, Amena Archer, Cecilia Williams

BMC Biol. 2023; 21: 277. Published online 2023 Nov 29. doi: 10.1186/s12915-023-01773-1

PMCID:: PMC10688478

Abstract Article PDF–3.9M

Select item 106239716.

LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis

Jijia Hu, Zongwei Zhang, Hongtu Hu, Keju Yang, Zijing Zhu, Qian Yang, Wei Liang

Cell Prolif. 2023 Nov; 56(11): e13479. Published online 2023 Apr 13. doi: 10.1111/cpr.13479

PMCID:: PMC10623971

Abstract Article PDF–6.3M

Select item 104127317.

Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia

Rizaldy C. Zapata, Dinghong Zhang, Avraham Libster, Alessandra Porcu, Patricia Montilla-Perez, Aisha Nur, Baijie Xu, Zhi Zhang, Stephanie M. Correa, Chen Liu, Francesca Telese, Olivia Osborn

Mol Psychiatry. 2023; 28(5): 1857–1867. Published online 2023 Feb 10. doi: 10.1038/s41380-023-01981-9

PMCID:: PMC10412731

Abstract Article PDF–1.6M

Select item 104107178.

Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120

PMCID:: PMC10410717

Abstract Article PDF–3.9M

Select item 103997099.

Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids

Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Feodora Kostadinova, Corinne Urwyler, Verena M. Merk, Mario Noti, Israel Toja da Silva, Konstantin Bode, Fatima Nahle, Anna Pia Plazzo, Julia Koerner, Regula Stuber, Constantin Menche, Eva Karamitopoulou, Henner F. Farin, Kenneth J. Gollob, Thomas Brunner

Mol Oncol. 2023 Aug; 17(8): 1545–1566. Published online 2023 Mar 9. doi: 10.1002/1878-0261.13414

PMCID:: PMC10399709

Abstract Article PDF–3.7M

Select item 1039049210.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1029010211.

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Isidoro Cobo, Sumit Paliwal, Cristina Bodas, Irene Felipe, Júlia Melià-Alomà, Ariadna Torres, Jaime Martínez-Villarreal, Marina Malumbres, Fernando García, Irene Millán, Natalia del Pozo, Joo-Cheol Park, Ray J. MacDonald, Javier Muñoz, Raúl Méndez, Francisco X. Real

Nat Commun. 2023; 14: 3761. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39291-x

PMCID:: PMC10290102

Abstract Article PDF–3.4M

Select item 1012089212.

NR5A2 as a potential target for exercise to improve metabolic syndrome

Lingxiu Meng, Fusheng Dong, Junguo Deng

Aging (Albany NY) 2023 Apr 15; 15(7): 2485–2502. Published online 2023 Mar 26. doi: 10.18632/aging.204606

PMCID:: PMC10120892

Abstract Article PDF–4.4M

Select item 1005011813.

Nuclear Receptor Nr5a2 Promotes Diverse Connective Tissue Fates in the Jaw

Hung-Jhen Chen, Lindsey Barske, Jared C. Talbot, Olivia M. Dinwoodie, Ryan R. Roberts, D’Juan T. Farmer, Christian Jimenez, Amy E. Merrill, Abigail S. Tucker, J. Gage Crump

Dev Cell. Author manuscript; available in PMC 2024 Mar 27.

Published in final edited form as: Dev Cell. 2023 Mar 27; 58(6): 461–473.e7. Published online 2023 Mar 10. doi: 10.1016/j.devcel.2023.02.011

PMCID:: PMC10050118

Abstract Article PDF–3.1M

Select item 942117714.

Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes

Arisa Shintani, Shoko Fukai, Reika Nobusawa, Kanako Taniguchi, Tomohiro Hatatani, Hayato Nagai, Tomohiro Sakai, Takuji Yoshimura, Masayuki Miyasaka, Haruko Hayasaka

Curr Res Immunol. 2022; 3: 175–185. Published online 2022 Aug 21. doi: 10.1016/j.crimmu.2022.08.008

PMCID:: PMC9421177

Abstract Article PDF–13M

Select item 911788315.

NR5A2/LRH-1 regulates the PTGS2-PGE₂-PTGER1 pathway contributing to pancreatic islet survival and function

Eugenia Martin Vázquez, Nadia Cobo-Vuilleumier, Raquel Araujo Legido, Sandra Marín-Cañas, Emanuele Nola, Akaitz Dorronsoro, Lucia López Bermudo, Alejandra Crespo, Silvana Y. Romero-Zerbo, Maria García-Fernández, Alejandro Martin Montalvo, Anabel Rojas, Valentine Comaills, Francisco J. Bérmudez-Silva, Maureen Gannon, Franz Martin, Decio Eizirik, Petra I. Lorenzo, Benoit R. Gauthier

iScience. 2022 May 20; 25(5): 104345. Published online 2022 May 2. doi: 10.1016/j.isci.2022.104345

PMCID:: PMC9117883

Abstract Article PDF–5.0M

Select item 889672016.

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis

Kellie S. Agrimson, Anna Minkina, Danielle Sadowski, Andrew Wheeler, Mark W. Murphy, Micah D. Gearhart, Vivian J. Bardwell, David Zarkower

PLoS Genet. 2022 Feb; 18(2): e1010088. Published online 2022 Feb 22. doi: 10.1371/journal.pgen.1010088

PMCID:: PMC8896720

Abstract Article PDF–9.3M

Select item 850523317.

Perilipin 5 is a novel target of nuclear receptor LRH-1 to regulate hepatic triglycerides metabolism

Rubee Pantha, Jae-Ho Lee, Jae-Hoon Bae, Eun Hee Koh, Minsang Shin, Dae-Kyu Song, Seung-Soon Im

BMB Rep. 2021 Sep 30; 54(9): 476–481. Published online 2021 Sep 30. doi: 10.5483/BMBRep.2021.54.9.051

PMCID:: PMC8505233

Abstract Article PDF–1.5M

Select item 845194118.

The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency

Nicola Festuccia, Nick Owens, Almira Chervova, Agnès Dubois, Pablo Navarro

Development. 2021 Sep 1; 148(17): dev199604. Published online 2021 Sep 10. doi: 10.1242/dev.199604

PMCID:: PMC8451941

Abstract Article

Select item 825156219.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629