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Items: 1 to 20 of 14372

1.
Molecular cascade reveals sequential milestones underlying hippocampal neural stem cell development into an adult state
Dennisse Jimenez-Cyrus, Vijay S. Adusumilli, Max H. Stempel, Sandra Maday, Guo-li Ming, Hongjun Song, Allison M. Bond
Cell Rep. Author manuscript; available in PMC 2024 Aug 13.
Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114339. Published online 2024 Jun 8. doi: 10.1016/j.celrep.2024.114339
PMCID:
PMC11320877
AbstractArticlePDF–3.7M
2.
Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
Valentina Poli, Marco Di Gioia, Martha Sola-Visner, Francesca Granucci, Andrew L. Frelinger, III, Alan D. Michelson, Ivan Zanoni
Immunity. Author manuscript; available in PMC 2024 Aug 12.
Published in final edited form as: Immunity. 2022 Feb 8; 55(2): 224–236.e5. Published online 2022 Jan 6. doi: 10.1016/j.immuni.2021.12.002
PMCID:
PMC11318314
AbstractArticlePDF–2.2M
3.
Intrinsic STAT4 expression controls effector CD4 T cell migration and Th17 pathogenicity
Ashlyn A. Buzzelli, Ian L. McWilliams, Boyoung Shin, Morgan T. Bryars, Laurie E. Harrington
J Immunol. Author manuscript; available in PMC 2024 Aug 6.
Published in final edited form as: J Immunol. 2023 Jun 1; 210(11): 1667–1676. doi: 10.4049/jimmunol.2200606
PMCID:
PMC11302403
AbstractArticlePDF–2.5M
4.
Generation of precision preclinical cancer models using regulated in vivo base editing
Alyna Katti, Adrián Vega-Pérez, Miguel Foronda, Jill Zimmerman, Maria Paz Zafra, Elizabeth Granowsky, Sukanya Goswami, Eric E. Gardner, Bianca J. Diaz, Janelle M Simon, Alexandra Wuest, Wei Luan, Maria Teresa Calvo Fernandez, Anastasia P. Kadina, John A Walker, II, Kevin Holden, Scott W. Lowe, Francisco J. Sánchez Rivera, Lukas E. Dow
Nat Biotechnol. Author manuscript; available in PMC 2024 Aug 2.
Published in final edited form as: Nat Biotechnol. 2024 Mar; 42(3): 437–447. Published online 2023 Aug 10. doi: 10.1038/s41587-023-01900-x
PMCID:
PMC11295146
AbstractArticlePDF–2.6M
5.
The primitive endoderm supports lineage plasticity to enable regulative development
Madeleine Linneberg-Agerholm, Annika Charlotte Sell, Alba Redó-Riveiro, Marta Perera, Martin Proks, Teresa E. Knudsen, Antonio Barral, Miguel Manzanares, Joshua M. Brickman
Cell. 2024 Jul 25; 187(15): 4010–4029.e16. doi: 10.1016/j.cell.2024.05.051
PMCID:
PMC11290322
AbstractArticle
6.
The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils
Heike Weighardt, Michael Shapiro, Michelle Mayer, Irmgard Förster, Brigitta Stockinger, Nicola Laura Diny
J Leukoc Biol. 2024 Aug; 116(2): 369–378. Published online 2024 May 3. doi: 10.1093/jleuko/qiae105
PMCID:
PMC11271977
AbstractArticlePDF–1.1M
7.
IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer
Lies van Baarle, Veronica De Simone, Linda Schneider, Sneha Santhosh, Saeed Abdurahiman, Francesca Biscu, Reiner Schneider, Lisa Zanoletti, Renata Siqueira de Mello, Sara Verbandt, Zedong Hu, Michelle Stakenborg, Bo-Jun Ke, Nathalie Stakenborg, Raquel Salvador Laureano, Balbina García-Reyes, Jonas Henn, Marieta Toma, Maxime Vanmechelen, Guy Boeckxstaens, Frederik De Smet, Abhishek D. Garg, Sales Ibiza, Sabine Tejpar, Sven Wehner, Gianluca Matteoli
Nat Commun. 2024; 15: 6079. Published online 2024 Jul 19. doi: 10.1038/s41467-024-50438-2
PMCID:
PMC11271635
AbstractArticlePDF–10M
8.
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression
Gloria Asantewaa, Emily T. Tuttle, Nathan P. Ward, Yun Pyo Kang, Yumi Kim, Madeline E. Kavanagh, Nomeda Girnius, Ying Chen, Katherine Rodriguez, Fabio Hecht, Marco Zocchi, Leonid Smorodintsev-Schiller, TashJaé Q. Scales, Kira Taylor, Fatemeh Alimohammadi, Renae P. Duncan, Zachary R. Sechrist, Diana Agostini-Vulaj, Xenia L. Schafer, Hayley Chang, Zachary R. Smith, Thomas N. O’Connor, Sarah Whelan, Laura M. Selfors, Jett Crowdis, G. Kenneth Gray, Roderick T. Bronson, Dirk Brenner, Alessandro Rufini, Robert T. Dirksen, Aram F. Hezel, Aaron R. Huber, Joshua Munger, Benjamin F. Cravatt, Vasilis Vasiliou, Calvin L. Cole, Gina M. DeNicola, Isaac S. Harris
Nat Commun. 2024; 15: 6152. Published online 2024 Jul 21. doi: 10.1038/s41467-024-50454-2
PMCID:
PMC11271484
AbstractArticlePDF–3.2M
9.
MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets
Eva Kane, Tracy C.S. Mak, Mathieu Latreille
iScience. 2024 Jul 19; 27(7): 110332. Published online 2024 Jun 20. doi: 10.1016/j.isci.2024.110332
PMCID:
PMC11269303
AbstractArticlePDF–5.7M
10.
Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory
Mikayla M. Voglewede, Elif Naz Ozsen, Noah Ivak, Matteo Bernabucci, Ruizhe Tang, Miao Sun, Zhiping P. Pang, Huaye Zhang
iScience. 2024 Jul 19; 27(7): 110308. Published online 2024 Jun 19. doi: 10.1016/j.isci.2024.110308
PMCID:
PMC11263792
AbstractArticlePDF–5.9M
11.
Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues
Sanjiv Neupane, Daniel B. Williamson, Robyn A. Roth, Carmen M. Halabi, Robert S. Haltiwanger, Bernadette C. Holdener
J Biol Chem. 2024 Jul; 300(7): 107445. Published online 2024 Jun 4. doi: 10.1016/j.jbc.2024.107445
PMCID:
PMC11261140
AbstractArticlePDF–8.6M
12.
Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus
Natalí B. Rasetto, Damiana Giacomini, Ariel A. Berardino, Tomás Vega Waichman, Maximiliano S. Beckel, Daniela J. Di Bella, Juliana Brown, M. Georgina Davies-Sala, Chiara Gerhardinger, Dieter Chichung Lie, Paola Arlotta, Ariel Chernomoretz, Alejandro F. Schinder
Sci Adv. 2024 Jul 19; 10(29): eadp6039. Published online 2024 Jul 19. doi: 10.1126/sciadv.adp6039
PMCID:
PMC11259177
AbstractArticlePDF–12M
13.
A fibronectin gradient remodels mixed-phase mesoderm
Min Zhu, Bin Gu, Evan C. Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M. Yung, Xin Chen, Kaiwen Zhang, Elizabeth K. Woolaver, Mikaela R. Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun, Sevan Hopyan
Sci Adv. 2024 Jul 19; 10(29): eadl6366. Published online 2024 Jul 19. doi: 10.1126/sciadv.adl6366
PMCID:
PMC11259159
AbstractArticlePDF–6.7M
14.
Acetylcholine Neurons Become Cholinergic during Three Time Windows in the Developing Mouse Brain
Rene Oliver Goral, Patricia W. Lamb, Jerrel L. Yakel
eNeuro. 2024 Jul; 11(7): ENEURO.0542-23.2024. Prepublished online 2024 Jun 28. Published online 2024 Jul 11. doi: 10.1523/ENEURO.0542-23.2024
PMCID:
PMC11253243
AbstractArticlePDF–14M
15.
Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture
Alice Braga, Martina Chiacchiaretta, Luc Pellerin, Dong Kong, Philip G. Haydon
Nat Commun. 2024; 15: 5979. Published online 2024 Jul 16. doi: 10.1038/s41467-024-50166-7
PMCID:
PMC11252394
AbstractArticlePDF–15M
16.
Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning
George R. Bjorklund, Katherina P. Rees, Kavya Balasubramanian, Lauren T. Hewitt, Kenji Nishimura, Jason M. Newbern
Dis Model Mech. 2024 Jun 1; 17(6): dmm050570. Published online 2024 Jul 2. doi: 10.1242/dmm.050570
PMCID:
PMC11247507
AbstractArticle
17.
Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression
Sara Zahraeifard, Zhiguang Xiao, Jae Young So, Abdul Ahad, Selina Montoya, Woo Yong Park, Trinadharao Sornapudi, Tiffany Andohkow, Abigail Read, Noemi Kedei, Vishal Koparde, Howard Yang, Maxwell Lee, Nathan Wong, Maggie Cam, Kun Wang, Eytan Ruppin, Ji Luo, Christine Hollander, Li Yang
Nat Commun. 2024; 15: 5873. Published online 2024 Jul 12. doi: 10.1038/s41467-024-50262-8
PMCID:
PMC11245525
AbstractArticlePDF–5.4M
18.
Robust reprogramming of glia into neurons by inhibition of Notch signaling and nuclear factor I (NFI) factors in adult mammalian retina
Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw, Thanh Hoang
Sci Adv. 2024 Jul 12; 10(28): eadn2091. Published online 2024 Jul 12. doi: 10.1126/sciadv.adn2091
PMCID:
PMC11244444
AbstractArticlePDF–7.9M
19.
Gut epithelial Interleukin-17 receptor A signaling can modulate distant tumors growth through microbial regulation
Vidhi Chandra, Le Li, Olivereen Le Roux, Yu Zhang, Rian M. Howell, Dhwani N. Rupani, Seyda Baydogan, Haiyan D. Miller, Erick Riquelme, Joseph Petrosino, Michael P. Kim, Krishnan P.L. Bhat, James R. White, Jay K. Kolls, Yuliya Pylayeva-Gupta, Florencia McAllister
Cancer Cell. Author manuscript; available in PMC 2024 Jul 11.
Published in final edited form as: Cancer Cell. 2024 Jan 8; 42(1): 85–100.e6. Published online 2023 Dec 28. doi: 10.1016/j.ccell.2023.12.006
PMCID:
PMC11238637
AbstractArticlePDF–2.3M
20.
A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism
Alexandra B. Ysasi, Anna E. Engler, Pushpinder Singh Bawa, Feiya Wang, Regan D. Conrad, Anthony K. Yeung, Jason R. Rock, Jennifer Beane-Ebel, Sarah A. Mazzilli, Ruth A. Franklin, Joseph P. Mizgerd, George J. Murphy
iScience. 2024 Jul 19; 27(7): 110169. Published online 2024 Jun 4. doi: 10.1016/j.isci.2024.110169
PMCID:
PMC11238131
AbstractArticlePDF–7.5M

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