PMC Links for GEO Profiles (Select 89725191) - PMC

Select item 105439951.

TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP

Jiajia Hu, Runjie Huang, Chengcai Liang, Yingnan Wang, Min Wang, Yanxing Chen, Chenyi Wu, Jinling Zhang, Zekun Liu, Qi Zhao, Zexian Liu, Feng Wang, Shuqiang Yuan

Mol Cancer Res. 2023 Oct 2; 21(10): 1107–1119. Published online 2023 Jul 6. doi: 10.1158/1541-7786.MCR-23-0113

PMCID:: PMC10543995

Abstract Article PDF–14M

Select item 98491412.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 96388643.

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization

Yueke Lin, Xiaoting Lv, Caiyu Sun, Yanlin Sun, Min Yang, Dapeng Ma, Weiqiang Jing, Yunxue Zhao, Yeping Cheng, Haocheng Xuan, Lihui Han

EMBO Rep. 2022 Nov; 23(11): e54569. Published online 2022 Sep 30. doi: 10.15252/embr.202154569

PMCID:: PMC9638864

Abstract Article PDF–2.8M

Select item 84589094.

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1

Rongkun Li, Lili Zhu, Yangxizi Peng, Xiaoxin Zhang, Chunhua Dai, Dejun Liu

Front Oncol. 2021; 11: 695740. Published online 2021 Sep 9. doi: 10.3389/fonc.2021.695740

PMCID:: PMC8458909

Abstract Article PDF–3.4M

Select item 79484525.

A conserved acetylation switch enables pharmacological control of tubby-like protein stability

Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard

J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839

PMCID:: PMC7948452

Abstract Article PDF–3.6M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 59642487.

TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation

Xiaoxiao Ma, Xiaomin Ma, Yumin Qiu, Lihui Zhu, Yueke Lin, Yajing You, Dapeng Ma, Zhenzhi Qin, Caiyu Sun, Yunxue Zhao, Yanlin Sun, Lihui Han

Cell Death Dis. 2018 Jun; 9(6): 608. Published online 2018 May 22. doi: 10.1038/s41419-018-0644-4

Correction in:: Cell Death Dis. 2018 Oct; 9(10): 1029.

PMCID:: PMC5964248

Abstract Article PDF–2.3M

Select item 41705858.

Genome-Wide Analysis of Polymorphisms Associated with Cytokine Responses in Smallpox Vaccine Recipients

Richard B. Kennedy, Inna G. Ovsyannikova, V. Shane Pankratz, Iana H. Haralambieva, Robert A. Vierkant, Gregory A. Poland

Hum Genet. Author manuscript; available in PMC 2014 Sep 22.

Published in final edited form as: Hum Genet. 2012 Sep; 131(9): 1403–1421. Published online 2012 May 19. doi: 10.1007/s00439-012-1174-2

PMCID:: PMC4170585

Abstract Article PDF–594K

Select item 34006289.

TRIM27 Negatively Regulates NOD2 by Ubiquitination and Proteasomal Degradation

Birte Zurek, Ida Schoultz, Andreas Neerincx, Luisa M. Napolitano, Katharina Birkner, Eveline Bennek, Gernot Sellge, Maria Lerm, Germana Meroni, Johan D. Söderholm, Thomas A. Kufer

PLoS One. 2012; 7(7): e41255. Published online 2012 Jul 19. doi: 10.1371/journal.pone.0041255

PMCID:: PMC3400628

Abstract Article PDF–832K

Select item 339221410.

The E3-Ubiquitin Ligase TRIM50 Interacts with HDAC6 and p62, and Promotes the Sequestration and Clearance of Ubiquitinated Proteins into the Aggresome

Carmela Fusco, Lucia Micale, Mikhail Egorov, Maria Monti, Ester Valentina D’Addetta, Bartolomeo Augello, Flora Cozzolino, Alessia Calcagnì, Andrea Fontana, Roman S. Polishchuk, Gerard Didelot, Alexandre Reymond, Piero Pucci, Giuseppe Merla

PLoS One. 2012; 7(7): e40440. Published online 2012 Jul 9. doi: 10.1371/journal.pone.0040440

PMCID:: PMC3392214

Abstract Article PDF–3.7M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 268006712.

Williams–Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase

Lucia Micale, Carmela Fusco, Bartolomeo Augello, Luisa MR Napolitano, Emmanouil T Dermitzakis, Germana Meroni, Giuseppe Merla, Alexandre Reymond

Eur J Hum Genet. Author manuscript; available in PMC 2009 May 11.

Published in final edited form as: Eur J Hum Genet. 2008 Sep; 16(9): 1038–1049. Published online 2008 Apr 9. doi: 10.1038/ejhg.2008.68

PMCID:: PMC2680067

Abstract Article PDF–2.0M

Select item 135612913.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 13924114.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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