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Select item 85352261.

Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn’s Disease

Daša Jevšinek Skok, Nina Hauptman, Miha Jerala, Nina Zidar

Genes (Basel) 2021 Oct; 12(10): 1477. Published online 2021 Sep 23. doi: 10.3390/genes12101477

PMCID:: PMC8535226

Abstract Article PDF–2.5M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71121963.

LEFTY2/endometrial bleeding-associated factor up-regulates Na⁺ Coupled Glucose Transporter SGLT1 expression and Glycogen Accumulation in Endometrial Cancer Cells

Ni Zeng, Toshiyuki Okumura, Md Alauddin, Shayan Khozooei, Janet Rajaxavier, Shaqiu Zhang, Yogesh Singh, Bing Shi, Sara Y. Brucker, Diethelm Wallwiener, Satoru Takeda, Florian Lang, Madhuri S. Salker

PLoS One. 2020; 15(4): e0230044. Published online 2020 Apr 1. doi: 10.1371/journal.pone.0230044

PMCID:: PMC7112196

Abstract Article PDF–1.4M

Select item 63033934.

Synthetic mammalian pattern formation driven by differential diffusivity of Nodal and Lefty

Ryoji Sekine, Tatsuo Shibata, Miki Ebisuya

Nat Commun. 2018; 9: 5456. Published online 2018 Dec 21. doi: 10.1038/s41467-018-07847-x

PMCID:: PMC6303393

Abstract Article PDF–4.1M

Select item 59512685.

The SMAD2/3 interactome reveals that TGFβ controls m⁶A mRNA methylation in pluripotency

Alessandro Bertero, Stephanie Brown, Pedro Madrigal, Anna Osnato, Daniel Ortmann, Loukia Yiangou, Juned Kadiwala, Nina C. Hubner, Igor Ruiz de los Mozos, Christoph Sadee, An-Sofie Lenaerts, Shota Nakanoh, Rodrigo Grandy, Edward Farnell, Jernej Ule, Hendrik G. Stunnenberg, Sasha Mendjan, Ludovic Vallier

Nature. Author manuscript; available in PMC 2018 Aug 28.

Published in final edited form as: Nature. 2018 Mar 8; 555(7695): 256–259. Published online 2018 Feb 28. doi: 10.1038/nature25784

PMCID:: PMC5951268

Abstract Article PDF–7.8M

Select item 57408916.

A functional role of LEFTY during progesterone therapy for endometrial carcinoma

Wu Fei, Daiki Kijima, Mami Hashimoto, Miki Hashimura, Yasuko Oguri, Sabine Kajita, Toshihide Matsumoto, Ako Yokoi, Makoto Saegusa

Cell Commun Signal. 2017; 15: 56. Published online 2017 Dec 21. doi: 10.1186/s12964-017-0211-0

PMCID:: PMC5740891

Abstract Article PDF–7.0M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49416468.

LeftyA decreases Actin Polymerization and Stiffness in Human Endometrial Cancer Cells

Madhuri S. Salker, Nicolas Schierbaum, Nour Alowayed, Yogesh Singh, Andreas F. Mack, Christos Stournaras, Tilman E. Schäffer, Florian Lang

Sci Rep. 2016; 6: 29370. Published online 2016 Jul 11. doi: 10.1038/srep29370

PMCID:: PMC4941646

Abstract Article PDF–1.3M

Select item 43809289.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 370818010.

Wnt3a-dependent and -independent Protein Interaction Networks of Chromatin-bound β-catenin in Mouse Embryonic Stem Cells

Toma Yakulov, Angelo Raggioli, Henriette Franz, Rolf Kemler

Mol Cell Proteomics. 2013 Jul; 12(7): 1980–1994. Published online 2013 Apr 15. doi: 10.1074/mcp.M112.026914

PMCID:: PMC3708180

Abstract Article PDF–2.1M

Select item 369664611.

Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

Despina Soteriou, Banu Iskender, Adam Byron, Jonathan D. Humphries, Simon Borg-Bartolo, Marie-Claire Haddock, Melissa A. Baxter, David Knight, Martin J. Humphries, Susan J. Kimber

J Biol Chem. 2013 Jun 28; 288(26): 18716–18731. Published online 2013 May 8. doi: 10.1074/jbc.M113.463372

PMCID:: PMC3696646

Abstract Article PDF–5.0M

Select item 326170812.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 296729714.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Abstract Article PDF–84K

Select item 294516815.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 290133616.

Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen, Lene Christiansen, Andrew Carl Lidral, Jeffrey Clark Murray

PLoS One. 2010; 5(7): e11493. Published online 2010 Jul 9. doi: 10.1371/journal.pone.0011493

PMCID:: PMC2901336

Abstract Article PDF–778K

Select item 277583217.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 277431718.

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

Irene Papageorgiou, Peter K Nicholls, Fang Wang, Martin Lackmann, Yogeshwar Makanji, Lois A Salamonsen, David M Robertson, Craig A Harrison

Reprod Biol Endocrinol. 2009; 7: 122. Published online 2009 Oct 29. doi: 10.1186/1477-7827-7-122

PMCID:: PMC2774317

Abstract Article PDF–3.3M

Select item 211415119.

Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells

J Cell Biol. 1986 Apr 1; 102(4): 1217–1223. doi: 10.1083/jcb.102.4.1217

PMCID:: PMC2114151

Summary PDF–813K

Select item 137778820.

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

K Kosaki, M T Bassi, R Kosaki, M Lewin, J Belmont, G Schauer, B Casey

Am J Hum Genet. 1999 Mar; 64(3): 712–721. doi: 10.1086/302289

PMCID:: PMC1377788

Summary PDF–516K

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