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Items: 1 to 20 of 43

1.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
2.
SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study
Xuefeng Wang, Wenqi Wang, Tiecheng Wang, Jianzhong Wang, Yuhang Jiang, Xue Wang, Ze Qiu, Na Feng, Weiyang Sun, Chang Li, Songtao Yang, Xianzhu Xia, Hongbin He, Yuwei Gao
J Virol. 2023 Mar; 97(3): e00011-23. Published online 2023 Mar 6. doi: 10.1128/jvi.00011-23
PMCID:
PMC10062165
AbstractArticlePDF–2.9M
3.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
4.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
5.
Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation
Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee
Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572
PMCID:
PMC8307194
AbstractArticlePDF–2.8M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer
Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li
Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502
PMCID:
PMC7905040
AbstractArticlePDF–3.2M
8.
Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation
Swati Roy, Amin Esmaeilniakooshkghazi, Srinivas Patnaik, Yaohong Wang, Sudeep P. George, Afzal Ahrorov, Jason K. Hou, Allan J. Herron, Hiromi Sesaki, Seema Khurana
Gastroenterology. Author manuscript; available in PMC 2021 Jan 14.
Published in final edited form as: Gastroenterology. 2018 Apr; 154(5): 1405–1420.e2. Published online 2017 Dec 21. doi: 10.1053/j.gastro.2017.12.016
PMCID:
PMC7808315
AbstractArticlePDF–1.3M
9.
Villin 1 is a predictive factor for the recurrence of high serum alpha‐fetoprotein‐associated hepatocellular carcinoma after hepatectomy
Maimaiti Xieraili, Mahmut Yasen, Kaoru Mogushi, Gulanbar Obulhasim, Abudureheman Mayinuer, Arihiro Aihara, Shinji Tanaka, Hiroshi Mizushima, Hiroshi Tanaka, Shigeki Arii
Cancer Sci. 2012 Aug; 103(8): 1493–1501. Published online 2012 May 25. doi: 10.1111/j.1349-7006.2012.02315.x
PMCID:
PMC7659241
AbstractArticlePDF–566K
10.
Transcriptome analysis uncovers the diagnostic value of miR-192-5p/HNF1A-AS1/VIL1 panel in cervical adenocarcinoma
Junfen Xu, Jian Zou, Luyao Wu, Weiguo Lu
Sci Rep. 2020; 10: 16584. Published online 2020 Oct 6. doi: 10.1038/s41598-020-73523-0
PMCID:
PMC7538942
AbstractArticlePDF–5.0M
11.
F–actin-bundling sites are conserved in proteins with villin-type headpiece domains
Sudeep P. George, Amin Esmaeilniakooshkghazi, Swati Roy, Seema Khurana
Mol Biol Cell. 2020 Aug 1; 31(17): 1857–1866. doi: 10.1091/mbc.E20-02-0158
PMCID:
PMC7525818
AbstractArticlePDF–3.0M
12.
Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease
Graham F. Brady, Raymond Kwan, Peter J. Ulintz, Phirum Nguyen, Shirin Bassirian, Venkatesha Basrur, Alexey I. Nesvizhskii, Rohit Loomba, M. Bishr Omary
Hepatology. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Hepatology. 2018 May; 67(5): 1710–1725. Published online 2018 Mar 24. doi: 10.1002/hep.29522
PMCID:
PMC5849478
AbstractArticlePDF–1.7M
13.
Clinicopathological, radiographic, and oncogenic features of primary pulmonary enteric adenocarcinoma in comparison with invasive adenocarcinoma in resection specimens
Long Zhao, Shanshan Huang, Jinjun Liu, Juan Zhao, Qiang Li, Huo-Qiang Wang
Medicine (Baltimore) 2017 Sep; 96(39): e8153. Published online 2017 Sep 29. doi: 10.1097/MD.0000000000008153
PMCID:
PMC5626302
AbstractArticlePDF–587K
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach
Qiuping Li, Yanmei Zhu, Jun Liu, Xiuwen Yu, Moye Chen, Nannan Dong, Yuehua Gong, Yuan Yuan
Sci Rep. 2017; 7: 2278. Published online 2017 May 23. doi: 10.1038/s41598-017-02642-y
PMCID:
PMC5442128
AbstractArticlePDF–3.1M
16.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
17.
N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression
Stephanie Holst, Anna J. M. Deuss, Gabi W. van Pelt, Sandra J. van Vliet, Juan J. Garcia-Vallejo, Carolien A. M. Koeleman, André M. Deelder, Wilma E. Mesker, Rob A. Tollenaar, Yoann Rombouts, Manfred Wuhrer
Mol Cell Proteomics. 2016 Jan; 15(1): 124–140. doi: 10.1074/mcp.M115.051235
PMCID:
PMC4762531
AbstractArticlePDF–3.2M
18.
By moonlighting in the nucleus, villin regulates epithelial plasticity
Srinivas Patnaik, Sudeep P. George, Eric Pham, Swati Roy, Kanchan Singh, John M. Mariadason, Seema Khurana
Mol Biol Cell. 2016 Feb 1; 27(3): 535–548. doi: 10.1091/mbc.E15-06-0453
PMCID:
PMC4751603
AbstractArticlePDF–4.1M
19.
Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases
Jun Yang, Yingxin Zhao, Mridul Kalita, Xueling Li, Mohammad Jamaluddin, Bing Tian, Chukwudi B. Edeh, John E. Wiktorowicz, Andrzej Kudlicki, Allan R. Brasier
Mol Cell Proteomics. 2015 Oct; 14(10): 2701–2721. Published online 2015 Jul 21. doi: 10.1074/mcp.M115.049221
PMCID:
PMC4597146
AbstractArticlePDF–4.5M
20.
Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase
Amol Bhargava, James A. Cotton, Brent R. Dixon, Lashitew Gedamu, Robin M. Yates, Andre G. Buret
PLoS One. 2015; 10(9): e0136102. Published online 2015 Sep 3. doi: 10.1371/journal.pone.0136102
PMCID:
PMC4559405
AbstractArticlePDF–4.8M

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