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Select item 110334451.

Lung-specific interleukin 6 mediated transglutaminase 2 activation and cardiopulmonary fibrogenesis

Krishna C. Penumatsa, Yamini Sharma, Rod R. Warburton, Adit Singhal, Deniz Toksoz, Chinmayee D. Bhedi, Guanming Qi, Ioana R. Preston, Christina Anderlind, Nicholas S. Hill, Barry L. Fanburg

Front Immunol. 2024; 15: 1371706. Published online 2024 Apr 8. doi: 10.3389/fimmu.2024.1371706

PMCID:: PMC11033445

Abstract Article PDF–4.1M

Select item 104871462.

Increased Osteoclastogenesis in Absence of TG2 Is Reversed by Transglutaminase Inhibition—Evidence for the Role for TG1 in Osteoclast Formation

Sahar Ebrahimi Samani, Mari T. Kaartinen

Cells. 2023 Sep; 12(17): 2139. Published online 2023 Aug 24. doi: 10.3390/cells12172139

PMCID:: PMC10487146

Abstract Article PDF–27M

Select item 104043063.

Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection

George M.H. Birchenough, Bjoern O. Schroeder, Sinan Sharba, Liisa Arike, Christian V. Recktenwald, Fabiola Puértolas-Balint, Mahadevan V. Subramani, Karl T. Hansson, Bahtiyar Yilmaz, Sara K. Lindén, Fredrik Bäckhed, Gunnar C. Hansson

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112084. Published online 2023 Feb 6. doi: 10.1016/j.celrep.2023.112084

PMCID:: PMC10404306

Abstract Article PDF–3.6M

Select item 103802754.

Transglutaminase 2 Facilitates Murine Wound Healing in a Strain-Dependent Manner

Ting W. Yiu, Sara R. Holman, Xenia Kaidonis, Robert M. Graham, Siiri E. Iismaa

Int J Mol Sci. 2023 Jul; 24(14): 11475. Published online 2023 Jul 14. doi: 10.3390/ijms241411475

PMCID:: PMC10380275

Abstract Article PDF–7.3M

Select item 102882735.

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Zhuo Yang, Xiao‐Wen Zhang, Fang‐Fang Zhuo, Ting‐Ting Liu, Qian‐Wei Luo, Yong‐Zhe Zheng, Ling Li, Heng Yang, Yi‐Chi Zhang, Yan‐Hang Wang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng

Adv Sci (Weinh) 2023 Jun; 10(18): 2206533. Published online 2023 Apr 23. doi: 10.1002/advs.202206533

PMCID:: PMC10288273

Abstract Article PDF–5.3M

Select item 100947096.

Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix

Jacen Emerson, Thomas Delgado, Peter Girardi, Gail V. W. Johnson

Int J Mol Sci. 2023 Apr; 24(7): 6058. Published online 2023 Mar 23. doi: 10.3390/ijms24076058

PMCID:: PMC10094709

Abstract Article PDF–3.2M

Select item 99805897.

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes

Wang Zheng, Qianping Chen, Hongxia Liu, Liang Zeng, Yuchuan Zhou, Xinglong Liu, Yang Bai, Jianghong Zhang, Yan Pan, Chunlin Shao

Autophagy. 2023; 19(3): 839–857. Published online 2022 Aug 1. doi: 10.1080/15548627.2022.2105562

PMCID:: PMC9980589

Abstract Article PDF–6.1M

Select item 99541008.

The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury

Ruo-Xi Shi, Cong Liu, Ya-Jie Xu, Ying-Ying Wang, Bao-Dong He, Xuan-Cheng He, Hong-Zhen Du, Baoyang Hu, Jianwei Jiao, Chang-Mei Liu, Zhao-Qian Teng

Cells. 2023 Feb; 12(4): 558. Published online 2023 Feb 9. doi: 10.3390/cells12040558

PMCID:: PMC9954100

Abstract Article PDF–27M

Select item 99113649.

Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes

Matthew C. Funsten, Leonid A. Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H. F. Hansen, Katharine I. Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky

Cell Host Microbe. Author manuscript; available in PMC 2024 Feb 8.

Published in final edited form as: Cell Host Microbe. 2023 Feb 8; 31(2): 213–227.e9. Published online 2023 Jan 4. doi: 10.1016/j.chom.2022.12.009

PMCID:: PMC9911364

Abstract Article PDF–1.5M

Select item 967545310.

Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells

Katharina Thomas, Lisa Zondler, Nadine Ludwig, Marina Kardell, Corinna Lüneburg, Katharina Henke, Sina Mersmann, Andreas Margraf, Tilmann Spieker, Tobias Tekath, Ana Velic, Richard Holtmeier, Juliane Hermann, Vera Jankowski, Melanie Meersch, Dietmar Vestweber, Martin Westphal, Johannes Roth, Michael A. Schäfers, John A. Kellum, Clifford A. Lowell, Jan Rossaint, Alexander Zarbock

JCI Insight. 2022 Nov 8; 7(21): e163161. Published online 2022 Nov 8. doi: 10.1172/jci.insight.163161

PMCID:: PMC9675453

Abstract Article PDF–14M

Select item 957870211.

Airway basal cells show regionally distinct potential to undergo metaplastic differentiation

Yizhuo Zhou, Ying Yang, Lihao Guo, Jun Qian, Jian Ge, Debora Sinner, Hongxu Ding, Andrea Califano, Wellington V Cardoso

eLife. 2022; 11: e80083. Published online 2022 Sep 30. doi: 10.7554/eLife.80083

PMCID:: PMC9578702

Abstract Article PDF–11M

Select item 936768512.

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation

Aїsha Callebaut, Ylke Bruggeman, Cloé Zamit, Fernanda Marques Câmara Sodré, Magali Irla, Chantal Mathieu, Mijke Buitinga, Lut Overbergh

Front Endocrinol (Lausanne) 2022; 13: 908248. Published online 2022 Jul 26. doi: 10.3389/fendo.2022.908248

PMCID:: PMC9367685

Abstract Article PDF–3.4M

Select item 934593913.

Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy

Zhaokang Cui, Yajuan Lu, Yilong Miao, Xiaoxin Dai, Yu Zhang, Bo Xiong

Cell Death Differ. 2022 Aug; 29(8): 1466–1473. Published online 2022 Jan 11. doi: 10.1038/s41418-022-00933-0

PMCID:: PMC9345939

Abstract Article PDF–3.8M

Select item 930422614.

Absence of tissue transglutaminase reduces amyloid‐beta pathology in APP23 mice

Micha M. M. Wilhelmus, Osoul Chouchane, Maarten Loos, Cornelis A. M. Jongenelen, John J. P. Brevé, Allert Jonker, John G. J. M. Bol, August B. Smit, Benjamin Drukarch

Neuropathol Appl Neurobiol. 2022 Jun; 48(4): e12796. Published online 2022 Feb 23. doi: 10.1111/nan.12796

PMCID:: PMC9304226

Abstract Article PDF–20M

Select item 903511215.

Cross-linking by tissue transglutaminase-2 alters fibrinogen-directed macrophage proinflammatory activity

Lauren G. Poole, Anna K. Kopec, Matthew J. Flick, James P. Luyendyk

J Thromb Haemost. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Thromb Haemost. 2022 May; 20(5): 1182–1192. Published online 2022 Feb 27. doi: 10.1111/jth.15670

PMCID:: PMC9035112

Abstract Article PDF–1.1M

Select item 877547116.

Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in Diabetes

Jae-Ah Seo, Nilofar Danishmalik Sayyed, Yeon-Ju Lee, Hye-Yoon Jeon, Eun-Bin Kim, Seok-Ho Hong, Soyeon Cho, Minsoo Kim, Kwon-Soo Ha

Int J Mol Sci. 2022 Jan; 23(2): 753. Published online 2022 Jan 11. doi: 10.3390/ijms23020753

PMCID:: PMC8775471

Abstract Article PDF–3.3M

Select item 862365417.

Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice

Zsófia Budai, Nour Al-Zaeed, Péter Szentesi, Hajnalka Halász, László Csernoch, Zsuzsa Szondy, Zsolt Sarang

Cells. 2021 Nov; 10(11): 3089. Published online 2021 Nov 9. doi: 10.3390/cells10113089

PMCID:: PMC8623654

Abstract Article PDF–4.3M

Select item 861611718.

Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury

Anissa Elahi, Jacen Emerson, Jacob Rudlong, Jeffrey W. Keillor, Garrick Salois, Adam Visca, Peter Girardi, Gail V.W. Johnson, Christoph Pröschel

Cells. 2021 Nov; 10(11): 2942. Published online 2021 Oct 29. doi: 10.3390/cells10112942

PMCID:: PMC8616117

Abstract Article PDF–4.6M

Select item 856574319.

TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease

Christian B. Lindstad, Alisa E. Dewan, Jorunn Stamnaes, Ludvig M. Sollid, M. Fleur du Pré

PLoS One. 2021; 16(11): e0259082. Published online 2021 Nov 3. doi: 10.1371/journal.pone.0259082

PMCID:: PMC8565743

Abstract Article PDF–1.5M

Select item 832209120.

Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2-C277S mouse model

Huilei Wang, James Chen, Sandeep Jandu, Sean Melucci, William Savage, Kavitha Nandakumar, Sara K. Kang, Sebastian Barreto-Ortiz, Alan Poe, Shivam Rastogi, Maria Bauer, Jochen Steppan, Lakshmi Santhanam

Cell Death Discov. 2021; 7: 197. Published online 2021 Jul 29. doi: 10.1038/s41420-021-00543-8

PMCID:: PMC8322091

Abstract Article PDF–4.6M

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