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Select item 104626261.

Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization

Lei Yue, Xiaozhang Xu, Shipeng Dai, Fan Xu, Wenhu Zhao, Jian Gu, Xinzheng Dai, Xiaofeng Qian

Sci Rep. 2023; 13: 14092. Published online 2023 Aug 28. doi: 10.1038/s41598-023-40404-1

PMCID:: PMC10462626

Abstract Article PDF–8.5M

Select item 97419672.

DDX24 promotes metastasis by regulating RPL5 in non‐small cell lung cancer

Xinyan Hu, Fangfang Li, Yulan Zhou, Hairun Gan, Tiancheng Wang, Luting Li, Haoyu Long, Bing Li, Pengfei Pang

Cancer Med. 2022 Dec; 11(23): 4513–4525. Published online 2022 Jul 21. doi: 10.1002/cam4.4835

PMCID:: PMC9741967

Abstract Article PDF–25M

Select item 95893123.

ORM 1 as a biomarker of increased vascular invasion and decreased sorafenib sensitivity in hepatocellular carcinoma

Jiangning Gu, Shiqi Xu, Xiang Chen, Haifeng Luo, Guang Tan, Wenjing Qi, Feng Ling, Chenqi Wang, Feiliyan Maimaiti, Yunlong Chen, Lili Yang, Menghong Yin, Dan Chen

Bosn J Basic Med Sci. 2022 Dec; 22(6): 949–958. Published online 2022 Jun 29. doi: 10.17305/bjbms.2022.7268

PMCID:: PMC9589312

Abstract Article PDF–2.6M

Select item 92517124.

Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk

Sonia Lopez, Angel Martinez-Perez, Alba Rodriguez-Rius, Ana Viñuela, Andrew A. Brown, Laura Martin-Fernandez, Noelia Vilalta, Marc Arús, Nikolaos I. Panousis, Alfonso Buil, Maria Sabater-Lleal, Juan Carlos Souto, Emmanouil T. Dermitzakis, Jose Manuel Soria

Thromb Haemost. 2022 Jun; 122(6): 1027–1039. Published online 2022 Mar 10. doi: 10.1055/s-0041-1742169

PMCID:: PMC9251712

Abstract Article PDF–2.5M

Select item 91714115.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 89739936.

Characterization of alpha-1-acid glycoprotein as a potential biomarker for breast cancer

Luo Qiong, Jun Yin

Bioengineered. 2022; 13(3): 5818–5826. Published online 2022 Feb 21. doi: 10.1080/21655979.2022.2036303

PMCID:: PMC8973993

Abstract Article PDF–1.1M

Select item 89235207.

Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils.

Mosale Seetharam Sumanth, Shancy P Jacob, Kandahalli Venkataranganayaka Abhilasha, Bhanu Kanth Manne, Venkatesha Basrur, Sylvain Lehoux, Robert A Campbell, Christian C Yost, Thomas M McIntyre, Richard D Cummings, Andrew S Weyrich, Matthew T Rondina, Gopal K Marathe

J Leukoc Biol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: J Leukoc Biol. 2021 May; 109(5): 915–930. Published online 2020 Oct 18. doi: 10.1002/JLB.3A0720-422R

PMCID:: PMC8923520

Abstract Article PDF–2.5M

Select item 88069428.

Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9

Luo Qiong, Jun Yin

Bioengineered. 2021; 12(1): 8822–8832. Published online 2021 Oct 27. doi: 10.1080/21655979.2021.1987067

PMCID:: PMC8806942

Abstract Article PDF–1.9M

Select item 86719399.

The structural basis for high affinity binding of α1-acid glycoprotein to the potent antitumor compound UCN-01

Erik J.B. Landin, Christopher Williams, Sara A. Ryan, Alice Bochel, Nahida Akter, Christina Redfield, Richard B. Sessions, Neesha Dedi, Richard J. Taylor, Matthew P. Crump

J Biol Chem. 2021 Dec; 297(6): 101392. Published online 2021 Nov 7. doi: 10.1016/j.jbc.2021.101392

PMCID:: PMC8671939

Abstract Article PDF–3.0M

Select item 866137510.

Orosomucoid in liver diseases

Gulsum Ozlem Elpek

World J Gastroenterol. 2021 Dec 7; 27(45): 7739–7747. Published online 2021 Dec 7. doi: 10.3748/wjg.v27.i45.7739

PMCID:: PMC8661375

Abstract Article PDF–435K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 678721613.

Fucosylated α₁-acid glycoprotein as a biomarker to predict prognosis following tumor immunotherapy of patients with lung cancer

Takehiko Yokobori, Shin Yazawa, Takayuki Asao, Nobuhiro Nakazawa, Akira Mogi, Rie Sano, Hiroyuki Kuwano, Kyoichi Kaira, Ken Shirabe

Sci Rep. 2019; 9: 14503. Published online 2019 Oct 10. doi: 10.1038/s41598-019-51021-2

PMCID:: PMC6787216

Abstract Article PDF–2.8M

Select item 668900314.

Evaluation of AGP Fucosylation as a Marker for Hepatocellular Carcinoma of Three Different Etiologies

Jing Liang, Jianhui Zhu, Mengmeng Wang, Amit G. Singal, Mobolaji Odewole, Sofia Kagan, Veronica Renteria, Suyu Liu, Neehar D. Parikh, David M. Lubman

Sci Rep. 2019; 9: 11580. Published online 2019 Aug 9. doi: 10.1038/s41598-019-48043-1

PMCID:: PMC6689003

Abstract Article PDF–3.2M

Select item 565200615.

Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes

Xian-Yang Qin, Mitsuko Hara, Erik Arner, Yoshikuni Kawaguchi, Ikuyo Inoue, Hideki Tatsukawa, Yutaka Furutani, Keisuke Nagatsuma, Tomokazu Matsuura, Feifei Wei, Jun Kikuchi, Hideko Sone, Carsten Daub, Hideya Kawaji, Timo Lassmann, Masayoshi Itoh, Harukazu Suzuki, Piero Carninci, Yoshihide Hayashizaki, the FANTOM consortium, Norihiro Kokudo, Alistair R.R. Forrest, Soichi Kojima

EBioMedicine. 2017 Oct; 24: 257–266. Published online 2017 Sep 12. doi: 10.1016/j.ebiom.2017.09.008

PMCID:: PMC5652006

Abstract Article PDF–1.3M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 541270817.

α1-acid Glycoprotein Induced Effects in Rat Brain Microvessel Endothelial Cells

Shuangling Zhang, Karen Mark

Microvasc Res. Author manuscript; available in PMC 2017 May 2.

Published in final edited form as: Microvasc Res. 2012 Sep; 84(2): 161–168. Published online 2012 May 25. doi: 10.1016/j.mvr.2012.05.003

PMCID:: PMC5412708

Article PDF–941K

Select item 508109618.

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya Otsu, Manuel Mayr

Circulation. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Circulation. 2016 Sep 13; 134(11): 817–832. Published online 2016 Aug 24. doi: 10.1161/CIRCULATIONAHA.115.016423

PMCID:: PMC5081096

Abstract Article PDF–2.5M

Select item 487287919.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 481036420.

S100A9 and ORM1 serve as predictors of therapeutic response and prognostic factors in advanced extranodal NK/T cell lymphoma patients treated with pegaspargase/gemcitabine

Zhiyuan Zhou, Zhaoming Li, Zhenchang Sun, Xudong Zhang, Lisha Lu, Yingjun Wang, Mingzhi Zhang

Sci Rep. 2016; 6: 23695. Published online 2016 Mar 29. doi: 10.1038/srep23695

PMCID:: PMC4810364

Abstract Article PDF–734K

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