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Select item 106522751.

Racial Differences in XO (Xanthine Oxidase) and Mitochondrial DNA Damage-Associated Molecular Patterns in Resistant Hypertension

Brittany Butts, Jamelle A Brown, Thomas S Denney, Jr., Scott Ballinger, Steven G Lloyd, Suzanne Oparil, Paul Sanders, Tony R Merriman, Angelo Gaffo, Jasvinder Singh, Eric Kelly, David A Calhoun, Louis J Dell’Italia

Hypertension. Author manuscript; available in PMC 2023 Nov 16.

Published in final edited form as: Hypertension. 2022 Apr; 79(4): 775–784. Published online 2022 Feb 15. doi: 10.1161/HYPERTENSIONAHA.121.18298

PMCID:: PMC10652275

Abstract Article PDF–1.0M

Select item 105118152.

Natural mutations of human XDH promote the nitrite (NO₂⁻)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?

G. Massimo, R.S. Khambata, T. Chapman, K. Birchall, C. Raimondi, A. Shabbir, Nicki Dyson, K.S. Rathod, C. Borghi, A. Ahluwalia

Redox Biol. 2023 Nov; 67: 102864. Published online 2023 Sep 4. doi: 10.1016/j.redox.2023.102864

Correction in:: Redox Biol. 2023 Nov; 67: 102925.

PMCID:: PMC10511815

Abstract Article PDF–11M

Select item 103242263.

Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure

Li Gao, Nicholas Rafaels, Tanda M. Dudenkov, Mahendra Damarla, Rachel Damico, James P. Maloney, Marc Moss, Greg S. Martin, Jonathan Sevransky, Carl Shanholtz, Dan L. Herr, Joe G.N. Garcia, Tamara Hernandez-Beeftink, Jesús Villar, Carlos Flores, Terri H. Beaty, Roy Brower, Paul M. Hassoun, Kathleen C. Barnes

Respir Res. 2023; 24: 177. Published online 2023 Jul 6. doi: 10.1186/s12931-023-02481-8

PMCID:: PMC10324226

Abstract Article PDF–1.4M

Select item 99325694.

The clinical value of serum xanthine oxidase levels in patients with acute ischemic stroke

Hailong Yu, Xin Chen, Xin Guo, Danni Chen, Li Jiang, Yajie Qi, Jun Shao, Luhang Tao, Jing Hang, Guangyu Lu, Yingzhu Chen, Yuping Li

Redox Biol. 2023 Apr; 60: 102623. Published online 2023 Feb 1. doi: 10.1016/j.redox.2023.102623

PMCID:: PMC9932569

Abstract Article PDF–4.1M

Select item 92792855.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92066666.

Possible role of insulin resistance in activation of plasma xanthine oxidoreductase in health check-up examinees

Masafumi Kurajoh, Shinya Fukumoto, Seigo Akari, Takayo Murase, Takashi Nakamura, Kanae Takahashi, Hisako Yoshida, Shinya Nakatani, Akihiro Tsuda, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Kazuto Hirata, Masanori Emoto

Sci Rep. 2022; 12: 10281. Published online 2022 Jun 18. doi: 10.1038/s41598-022-11094-y

PMCID:: PMC9206666

Abstract Article PDF–1.0M

Select item 88295497.

Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression

Huanhuan Wang, Lingzhu Xie, Xuhong Song, Jing Wang, Xinyan Li, Zhike Lin, Ting Su, Bin Liang, Dongyang Huang

Front Immunol. 2022; 13: 773001. Published online 2022 Jan 27. doi: 10.3389/fimmu.2022.773001

PMCID:: PMC8829549

Abstract Article PDF–5.1M

Select item 84741038.

Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults

Juan Manuel Vargas-Morales, Martha Guevara-Cruz, Celia Aradillas-García, Lilia G. Noriega, Armando Tovar, Jorge Alejandro Alegría-Torres

Version 2. F1000Res. 2021; 10: 217. Published online 2021 Sep 24. doi: 10.12688/f1000research.46399.2

PMCID:: PMC8474103

Abstract Article PDF–900K

Select item 83641819.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 835450010.

Plasma xanthine oxidoreductase activity in Japanese patients with type 2 diabetes across hospitalized treatment

Yusuke Kawachi, Yuya Fujishima, Hitoshi Nishizawa, Hirofumi Nagao, Takashi Nakamura, Seigo Akari, Takayo Murase, Naohiro Taya, Kazuo Omori, Akimitsu Miyake, Shiro Fukuda, Mitsuyoshi Takahara, Shunbun Kita, Naoto Katakami, Norikazu Maeda, Iichiro Shimomura

J Diabetes Investig. 2021 Aug; 12(8): 1512–1520. Published online 2020 Dec 18. doi: 10.1111/jdi.13467

PMCID:: PMC8354500

Abstract Article PDF–403K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 777194312.

Serum Level of Xanthine Oxidase, Uric Acid, and NADPH Oxidase 1 in Stage I of Multiple Myeloma

Maryam Kohsari, Mohammad Hassan Khadem Ansari, Yousef Rasmi

Asian Pac J Cancer Prev. 2020 Aug; 21(8): 2237–2242. doi: 10.31557/APJCP.2020.21.8.2237

PMCID:: PMC7771943

Abstract Article PDF–402K

Select item 745033913.

Local and Systemic Oxidative Stress in Balkan Endemic Nephropathy Is Not Associated with Xanthine Oxidase Activity

Andrej Veljković, Jovan Hadži- Đokić, Dušan Sokolović, Rade Čukuranović, Jovana Čukuranović-Kokoris, Dragoslav Bašić, Branka Đorđević, Marko Stojanović, Andrija Šmelcerović, Gordana Kocić

Oxid Med Cell Longev. 2020; 2020: 8209727. Published online 2020 Aug 18. doi: 10.1155/2020/8209727

PMCID:: PMC7450339

Abstract Article PDF–645K

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 677813715.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 659951816.

Xanthine oxidase is hyper-active in Duchenne muscular dystrophy

Angus Lindsay, Preston M. McCourt, Peter Karachunski, Dawn A. Lowe, James M. Ervasti

Free Radic Biol Med. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Free Radic Biol Med. 2018 Dec; 129: 364–371. Published online 2018 Oct 10. doi: 10.1016/j.freeradbiomed.2018.10.404

PMCID:: PMC6599518

Abstract Article PDF–760K

Select item 658843117.

Plasma Xanthine Oxidase Activity Is Related to Increased Sodium and Left Ventricular Hypertrophy in Resistant Hypertension

Brittany Butts, David A Calhoun, Thomas S Denney, Jr., Steven G Lloyd, Himanshu Gupta, Krishna K Gaddam, Inmaculada Aban, Suzanne Oparil, Paul W Sanders, Rakesh Patel, James F Collawn, Louis J Dell’Italia

Free Radic Biol Med. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Free Radic Biol Med. 2019 Apr; 134: 343–349. Published online 2019 Jan 26. doi: 10.1016/j.freeradbiomed.2019.01.029

PMCID:: PMC6588431

Abstract Article PDF–810K

Select item 614628718.

A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates

Zuzana Saidak, Christophe Louandre, Samy Dahmani, Chloé Sauzay, Sara Guedda, Bruno Chauffert, Denis Chatelain, Irene Ceballos-Picot, Antoine Galmiche

Biosci Rep. 2018 Oct 31; 38(5): BSR20171716. Prepublished online 2018 Aug 13. Published online 2018 Sep 19. doi: 10.1042/BSR20171716

PMCID:: PMC6146287

Abstract Article PDF–1.0M

Select item 588012719.

Hexokinase 2 and nuclear factor erythroid 2–related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells

Touseef Sheikh, Piyushi Gupta, Pruthvi Gowda, Shruti Patrick, Ellora Sen

J Biol Chem. 2018 Mar 30; 293(13): 4767–4777. Published online 2018 Feb 6. doi: 10.1074/jbc.M117.816785

PMCID:: PMC5880127

Abstract Article PDF–2.7M

Select item 581469920.

Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity

Mehdi A. Fini, Jeanette Gaydos, Alicia McNally, Vijaya Karoor, Ellen L. Burnham

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1; 313(6): L1047–L1057. Published online 2017 Aug 22. doi: 10.1152/ajplung.00570.2016

PMCID:: PMC5814699

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