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Items: 1 to 20 of 27

1.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
2.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
3.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
Marina Schrecker, Julia Korobenko, Richard K Hite
eLife. 2020; 9: e59555. Published online 2020 Aug 4. doi: 10.7554/eLife.59555
PMCID:
PMC7440919
AbstractArticlePDF–9.0M
6.
Molecular insights into the human CLC-7/Ostm1 transporter
Sensen Zhang, Yang Liu, Bing Zhang, Jun Zhou, Tianyu Li, Zhiqiang Liu, Yang Li, Maojun Yang
Sci Adv. 2020 Aug; 6(33): eabb4747. Published online 2020 Aug 12. doi: 10.1126/sciadv.abb4747
PMCID:
PMC7423370
AbstractArticlePDF–3.0M
7.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
8.
Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication
Chunqiang Ma, Wei Xu, Qingyu Yang, Weiyong Liu, Qi Xiang, Junbo Chen, Qi Zhang, Yingle Liu, Kailang Wu, Jianguo Wu
J Virol. 2020 Jun; 94(11): e01800-19. Prepublished online 2020 Mar 18. Published online 2020 May 18. doi: 10.1128/JVI.01800-19
PMCID:
PMC7269441
AbstractArticlePDF–4.7M
9.
Coexisting variants in OSTM1 and MANEAL cause a complex neurodegenerative disorder with NBIA-like brain abnormalities
Diran Herebian, Bader Alhaddad, Annette Seibt, Thomas Schwarzmayr, Katharina Danhauser, Dirk Klee, Stefani Harmsen, Thomas Meitinger, Tim M Strom, Ansgar Schulz, Ertan Mayatepek, Tobias B Haack, Felix Distelmaier
Eur J Hum Genet. 2017 Sep; 25(9): 1092–1095. Published online 2017 Jun 14. doi: 10.1038/ejhg.2017.96
PMCID:
PMC5558179
AbstractArticlePDF–1.1M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking
Subramanya N. M. Pandruvada, Janie Beauregard, Suzanne Benjannet, Monica Pata, Claude Lazure, Nabil G. Seidah, Jean Vacher
Mol Cell Biol. 2016 Feb 1; 36(3): 507–521. Prepublished online 2015 Nov 23. Published online 2016 Jan 19. doi: 10.1128/MCB.00656-15
PMCID:
PMC4719428
AbstractArticlePDF–4.0M
12.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
13.
Secretion of a Truncated Osteopetrosis-associated Transmembrane Protein 1 (OSTM1) Mutant Inhibits Osteoclastogenesis through Down-regulation of the B Lymphocyte-induced Maturation Protein 1 (BLIMP1)-Nuclear Factor of Activated T Cells c1 (NFATc1) Axis
Bongjin Shin, Jungeun Yu, Eui-Soon Park, Seunga Choi, Jiyeon Yu, Jung Me Hwang, Hyeongseok Yun, Young-Ho Chung, Kwan Soo Hong, Jong-Soon Choi, Masamichi Takami, Jaerang Rho
J Biol Chem. 2014 Dec 26; 289(52): 35868–35881. Published online 2014 Oct 30. doi: 10.1074/jbc.M114.589614
PMCID:
PMC4276856
AbstractArticlePDF–3.7M
14.
OSTM1 Regulates β-catenin/Lef1 Interaction and is Required for Wnt/β-catenin Signaling
Michael E. Feigin, Craig C. Malbon
Cell Signal. Author manuscript; available in PMC 2014 Dec 23.
Published in final edited form as: Cell Signal. 2008 May; 20(5): 949–957. Published online 2008 Jan 24. doi: 10.1016/j.cellsig.2008.01.009
PMCID:
PMC4275117
AbstractArticlePDF–4.5M
15.
Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions
Nicholas T. Woods, Rafael D. Mesquita, Michael Sweet, Marcelo A. Carvalho, Xueli Li, Yun Liu, Huey Nguyen, C. Eric Thomas, Edwin S. Iversen, Jr., Sylvia Marsillac, Rachel Karchin, John Koomen, Alvaro N.A. Monteiro
Sci Signal. Author manuscript; available in PMC 2014 Jun 20.
Published in final edited form as: Sci Signal. 2012; 5(242): rs6. Published online 2012 Sep 18. doi: 10.1126/scisignal.2002255
PMCID:
PMC4064718
AbstractArticlePDF–2.1M
16.
Severe Neurodegeneration with Impaired Autophagy Mechanism Triggered by Ostm1 Deficiency
Céline Héraud, Adam Griffiths, Subramanya N. M. Pandruvada, Manfred W. Kilimann, Monica Pata, Jean Vacher
J Biol Chem. 2014 May 16; 289(20): 13912–13925. Published online 2014 Apr 9. doi: 10.1074/jbc.M113.537233
PMCID:
PMC4022863
AbstractArticlePDF–3.4M
17.
Common Gating of Both CLC Transporter Subunits Underlies Voltage-dependent Activation of the 2Cl−/1H+ Exchanger ClC-7/Ostm1
Carmen F. Ludwig, Florian Ullrich, Lilia Leisle, Tobias Stauber, Thomas J. Jentsch
J Biol Chem. 2013 Oct 4; 288(40): 28611–28619. Published online 2013 Aug 27. doi: 10.1074/jbc.M113.509364
PMCID:
PMC3789960
AbstractArticlePDF–1.2M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
ClC-7 is a slowly voltage-gated 2Cl−/1H+-exchanger and requires Ostm1 for transport activity
Lilia Leisle, Carmen F Ludwig, Florian A Wagner, Thomas J Jentsch, Tobias Stauber
EMBO J. 2011 Jun 1; 30(11): 2140–2152. Published online 2011 Apr 28. doi: 10.1038/emboj.2011.137
PMCID:
PMC3117652
AbstractArticlePDF–1.6M
20.
High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men
Laura M. Yerges, Lambertus Klei, Jane A. Cauley, Kathryn Roeder, Candace M. Kammerer, Susan P. Moffett, Kristine E. Ensrud, Cara S. Nestlerode, Lynn M. Marshall, Andrew R. Hoffman, Cora Lewis, Thomas F. Lang, Elizabeth Barrett-Connor, Robert E. Ferrell, Eric S. Orwoll, Joseph M. Zmuda
J Bone Miner Res. 2009 Dec; 24(12): 2039–2049. Published online 2009 May 18. doi: 10.1359/JBMR.090524
PMCID:
PMC2791518
AbstractArticlePDF–759K

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