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Items: 1 to 20 of 172

1.
Reduced immune effector cell NKG2D expression and increased levels of soluble NKG2D ligands in multiple myeloma may not be causally linked
Marie von Lilienfeld-Toal, Susanne Frank, Christiane Leyendecker, Sylvia Feyler, Sarah Jarmin, Ruth Morgan, Axel Glasmacher, Angela Märten, Ingo G. H. Schmidt-Wolf, Peter Brossart, Gordon Cook
Cancer Immunol Immunother. 2010 Jun; 59(6): 829–839. Published online 2009 Dec 19. doi: 10.1007/s00262-009-0807-3
PMCID:
PMC11030819
AbstractArticlePDF–482K
2.
Elevated levels of cell-free NKG2D-ligands modulate NKG2D surface expression and compromise NK cell function in severe COVID-19 disease
Daniel Fernández-Soto, Álvaro F. García-Jiménez, José M. Casasnovas, Mar Valés-Gómez, Hugh T. Reyburn
Front Immunol. 2024; 15: 1273942. Published online 2024 Feb 12. doi: 10.3389/fimmu.2024.1273942
PMCID:
PMC10895954
AbstractArticlePDF–2.6M
3.
Autophagy-mediated NKG2D internalization impairs NK cell function and exacerbates radiation pneumonitis
Ruiqing Wang, Xinyue Ma, Xinyu Zhang, Dizhi Jiang, Hongyuan Mao, Zerun Li, Yu Tian, Bo Cheng
Front Immunol. 2023; 14: 1250920. Published online 2023 Nov 24. doi: 10.3389/fimmu.2023.1250920
PMCID:
PMC10704197
AbstractArticlePDF–7.5M
4.
Reovirus infection of tumor cells reduces the expression of NKG2D ligands, leading to impaired NK-cell cytotoxicity and functionality
Raghad Khaleafi, Jelena Zeleznjak, Sapir Cordela, Shani Drucker, Tihana Lenac Rovis, Stipan Jonjic, Yotam Bar-On
Front Immunol. 2023; 14: 1231782. Published online 2023 Sep 11. doi: 10.3389/fimmu.2023.1231782
PMCID:
PMC10518469
AbstractArticlePDF–4.3M
5.
IL-17a-producing γδT cells and NKG2D signaling mediate bacterial endotoxin-induced neonatal lung injury: implications for bronchopulmonary dysplasia
Tracy X. Cui, Alexander E. Brady, Ying-Jian Zhang, Chase Anderson, Antonia P. Popova
Front Immunol. 2023; 14: 1156842. Published online 2023 Sep 8. doi: 10.3389/fimmu.2023.1156842
PMCID:
PMC10514485
AbstractArticlePDF–9.2M
6.
NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis
Laís A. Sacramento, Camila Farias Amorim, Taís M. Campos, Maíra Saldanha, Sérgio Arruda, Lucas P. Carvalho, Daniel P. Beiting, Edgar M. Carvalho, Fernanda O. Novais, Phillip Scott
PLoS Negl Trop Dis. 2023 Aug; 17(8): e0011552. Published online 2023 Aug 21. doi: 10.1371/journal.pntd.0011552
PMCID:
PMC10470908
AbstractArticlePDF–1.5M
7.
Involvement of KLRK1 in immune infiltration of head and neck squamous cell carcinoma correlates with favorable prognosis
Haosheng Tan, Huaiyu Yang, Jiaxin Qian, Shaoyan Liu, Dangui Yan, Liyuan Wei, Wensheng Liu
Medicine (Baltimore) 2023 Aug 11; 102(32): e34761. Published online 2023 Aug 11. doi: 10.1097/MD.0000000000034761
PMCID:
PMC10419669
AbstractArticlePDF–3.1M
8.
Role of NKG2D ligands and receptor in haploidentical related donor hematopoietic cell transplantation
Effie W. Petersdorf, Caroline McKallor, Mari Malkki, Meilun He, Stephen R. Spellman, Katharine C. Hsu, Roland K. Strong, Ted Gooley, Phil Stevenson
Blood Adv. 2023 Jun 27; 7(12): 2888–2896. Published online 2023 Feb 11. doi: 10.1182/bloodadvances.2022008922
PMCID:
PMC10300293
AbstractArticlePDF–304K
9.
Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance
Jiemiao Hu, Xueqing Xia, Qingnan Zhao, Shulin Li
Cancer Lett. Author manuscript; available in PMC 2023 Apr 28.
Published in final edited form as: Cancer Lett. 2021 Apr 1; 502: 143–153. Published online 2020 Dec 3. doi: 10.1016/j.canlet.2020.12.002
PMCID:
PMC10142196
AbstractArticlePDF–1.7M
10.
NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells
Frederick J. Kohlhapp, Jeremy A. O’Sullivan, Tamson V. Moore, Andrew Zloza, José A. Guevara-Patiño
Mol Immunol. Author manuscript; available in PMC 2023 Mar 8.
Published in final edited form as: Mol Immunol. 2023 Mar; 155: 1–6. Published online 2023 Jan 10. doi: 10.1016/j.molimm.2022.12.013
PMCID:
PMC9992161
AbstractArticlePDF–1.0M
11.
NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes
Daniel R. Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J. Tian, Emily A. Aminian, Kristin M. Wang, Avishai Shemesh, Elman B. Punzalan, Aartik Sarma, Carolyn S. Calfee, Stephanie A. Christenson, Charles R. Langelier, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Rupal Shah, Aida Venado, Lewis L. Lanier, John R. Greenland, David M. Sayah, Abbas Ardehali, Jasleen Kukreja, S. Samuel Weigt, John A. Belperio, Jonathan P. Singer, Mark R. Looney
JCI Insight. 2022 Dec 22; 7(24): e164603. Published online 2022 Dec 22. doi: 10.1172/jci.insight.164603
PMCID:
PMC9869973
AbstractArticlePDF–1.5M
12.
IL-15 induced bystander activation of CD8+ T cells may mediate endothelium injury through NKG2D in Hantaan virus infection
Xiyue Zhang, Yusi Zhang, He Liu, Kang Tang, Chunmei Zhang, Meng Wang, Manling Xue, Xiaozhou Jia, Haifeng Hu, Na Li, Ran Zhuang, Boquan Jin, Fanglin Zhang, Yun Zhang, Ying Ma
Front Cell Infect Microbiol. 2022; 12: 1084841. Published online 2022 Dec 15. doi: 10.3389/fcimb.2022.1084841
PMCID:
PMC9797980
AbstractArticlePDF–4.7M
13.
SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D
Madeline J. Lee, Michelle W. Leong, Arjun Rustagi, Aimee Beck, Leiping Zeng, Susan Holmes, Lei S. Qi, Catherine A. Blish
Cell Rep. 2022 Dec 27; 41(13): 111892. Published online 2022 Dec 12. doi: 10.1016/j.celrep.2022.111892
PMCID:
PMC9742201
AbstractArticlePDF–3.9M
14.
Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Jian Zhong, Xuesong Yang, Junju Chen, Kejun He, Xinya Gao, Xujia Wu, Maolei Zhang, Huangkai Zhou, Feizhe Xiao, Lele An, Xiuxing Wang, Yu Shi, Nu Zhang
Nat Commun. 2022; 13: 4795. Published online 2022 Aug 15. doi: 10.1038/s41467-022-32311-2
PMCID:
PMC9378736
AbstractArticlePDF–6.9M
15.
GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells
Andrea Kosta, Abdelilah Mekhloufi, Lorenzo Lucantonio, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Angela Gismondi, Francesca Fazio, Maria Teresa Petrucci, Angela Santoni, Helena Stabile, Cinzia Fionda
Front Immunol. 2022; 13: 942640. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.942640
PMCID:
PMC9368199
AbstractArticlePDF–1.4M
16.
Spatially resolved in silico modeling of NKG2D signaling kinetics suggests a key role of NKG2D and Vav1 Co-clustering in generating natural killer cell activation
Rajdeep Kaur Grewal, Jayajit Das
PLoS Comput Biol. 2022 May; 18(5): e1010114. Published online 2022 May 18. doi: 10.1371/journal.pcbi.1010114
PMCID:
PMC9154193
AbstractArticlePDF–2.4M
17.
KLRK1 as a prognostic biomarker for lung adenocarcinoma cancer
Yanan Zhang, Zeyang Chen, Aifang Jiang, Guanqi Gao
Sci Rep. 2022; 12: 1976. Published online 2022 Feb 7. doi: 10.1038/s41598-022-05997-z
PMCID:
PMC8821622
AbstractArticlePDF–2.4M
18.
NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes
Juan Fan, Jiawei Shi, Yong Zhang, Junwei Liu, Chenyi An, Huaying Zhu, Peng Wu, Wei Hu, Rui Qin, Danmei Yao, Xin Shou, Yibing Xu, Zhou Tong, Xue Wen, Jianpo Xu, Jin Zhang, Weijia Fang, Jizhong Lou, Weiwei Yin, Wei Chen
EMBO J. 2022 Jan 17; 41(2): e107739. Published online 2021 Dec 16. doi: 10.15252/embj.2021107739
PMCID:
PMC8762575
AbstractArticlePDF–2.8M
19.
CEBPA mutants down-regulate AML cell susceptibility to NK-mediated lysis by disruption of the expression of NKG2D ligands, which can be restored by LSD1 inhibition
Meng Liu, Mengbao Du, Jian Yu, Zijun Qian, Yang Gao, Wenjue Pan, Xiujie Zhao, Mowang Wang, Huimin Li, Jiaqi Zheng, Qianshuo Huang, Li-Mengmeng Wang, Haowen Xiao
Oncoimmunology. 2022; 11(1): 2016158. Published online 2022 Jan 5. doi: 10.1080/2162402X.2021.2016158
PMCID:
PMC8741297
AbstractArticlePDF–2.3M
20.
Retargeting Interleukin-2 Signaling to NKG2D-Expressing Tumor Infiltrating Leukocytes Improves Adoptive Transfer Immunotherapy
Anirban Banerjee, Dongge Li, Yizhan Guo, Bayan Mahgoub, Lea Paragas, Jacqueline Slobin, Zhongcheng Mei, Amir Manafi, Atsushi Hata, Kang Li, Lei Shi, John Westwick, Craig Slingluff, Eric Lazear, Alexander Sasha Krupnick
J Immunol. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: J Immunol. 2021 Jul 1; 207(1): 333–343. Published online 2021 Jun 21. doi: 10.4049/jimmunol.2000926
PMCID:
PMC8688582
AbstractArticlePDF–2.3M

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