PMC Links for GEO Profiles (Select 81705818) - PMC

Links from GEO Profiles

Items: 1 to 20 of 146

<< First< Prev

Page of 8

Select item 104077471.

NPC1 plays a role in the trafficking of specific cargo to melanosomes

Alina Adriana Rus, Ioana V. Militaru, Ioana Popa, Cristian V.A. Munteanu, Livia Elena Sima, Nick Platt, Frances M. Platt, Ștefana M. Petrescu

J Biol Chem. 2023 Aug; 299(8): 105024. Published online 2023 Jul 7. doi: 10.1016/j.jbc.2023.105024

PMCID:: PMC10407747

Abstract Article PDF–3.9M

Select item 103825912.

NPC1-dependent alterations in K_V2.1–Ca_V1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease

Maria Casas, Karl D. Murray, Keiko Hino, Nicholas C. Vierra, Sergi Simó, James S. Trimmer, Rose E. Dixon, Eamonn J. Dickson

Nat Commun. 2023; 14: 4553. Published online 2023 Jul 28. doi: 10.1038/s41467-023-39937-w

PMCID:: PMC10382591

Abstract Article PDF–11M

Select item 102968513.

A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 Disease

Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, Dave Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul Rahim

Cells. 2023 Jun; 12(12): 1619. Published online 2023 Jun 13. doi: 10.3390/cells12121619

PMCID:: PMC10296851

Abstract Article PDF–3.9M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99031375.

Purification and structure of luminal domain C of human Niemann–Pick C1 protein

Laura Odongo, Kaneil K. Zadrozny, William E. Diehl, Jeremy Luban, Judith M. White, Barbie K. Ganser-Pornillos, Lukas K. Tamm, Owen Pornillos

Acta Crystallogr F Struct Biol Commun. 2023 Feb 1; 79(Pt 2): 45–50. Published online 2023 Feb 2. doi: 10.1107/S2053230X23000705

PMCID:: PMC9903137

Abstract Article PDF–723K

Select item 93485766.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92626147.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92316238.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 903755410.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 891997111.

NPC1-mTORC1 signaling Couples Cholesterol Sensing to Organelle Homeostasis and is a Targetable Pathway in Niemann-Pick type C

Oliver B. Davis, Hijai R. Shin, Chun-Yan Lim, Emma Y. Wu, Matthew Kukurugya, Claire F. Maher, Rushika M. Perera, M. Paulina Ordonez, Roberto Zoncu

Dev Cell. Author manuscript; available in PMC 2022 Mar 14.

Published in final edited form as: Dev Cell. 2021 Feb 8; 56(3): 260–276.e7. Published online 2020 Dec 11. doi: 10.1016/j.devcel.2020.11.016

PMCID:: PMC8919971

Abstract Article PDF–3.1M

Select item 879324712.

Identification of novel mutations among Iranian NPC1 patients: a bioinformatics approach to predict pathogenic mutations

Rezvan Abtahi, Parvaneh Karimzadeh, Omid Aryani, Diba Akbarzadeh, Shadab Salehpour, Alireza Rezayi, Seyed Hassan Tonekaboni, Reza Zolfaghari Emameh, Massoud Houshmand

Hereditas. 2022; 159: 8. Published online 2022 Jan 27. doi: 10.1186/s41065-022-00224-1

PMCID:: PMC8793247

Abstract Article PDF–1.1M

Select item 875583113.

Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

Jaimy Jose, Monira Hoque, Johanna Engel, Syed S. Beevi, Mohamed Wahba, Mariya Ilieva Georgieva, Kendelle J. Murphy, William E. Hughes, Blake J. Cochran, Albert Lu, Francesc Tebar, Andrew J. Hoy, Paul Timpson, Kerry-Anne Rye, Carlos Enrich, Carles Rentero, Thomas Grewal

Sci Rep. 2022; 12: 596. Published online 2022 Jan 12. doi: 10.1038/s41598-021-04584-y

PMCID:: PMC8755831

Abstract Article PDF–3.6M

Select item 862418214.

Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical Phenotype of Niemann-Pick Type C1 Disease

Christin Völkner, Maik Liedtke, Robert Untucht, Andreas Hermann, Moritz J. Frech

Int J Mol Sci. 2021 Nov; 22(22): 12184. Published online 2021 Nov 10. doi: 10.3390/ijms222212184

PMCID:: PMC8624182

Abstract Article PDF–24M

Select item 860779715.

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

Yu-Shiuan Cheng, Tianyi Zhang, Xiang Ma, Sarida Pratuangtham, Grace C. Zhang, Alexander A. Ondrus, Amirhossein Mafi, Brett Lomenick, Jeffrey J. Jones, Alison E. Ondrus

Nat Chem Biol. Author manuscript; available in PMC 2022 May 19.

Published in final edited form as: Nat Chem Biol. 2021 Dec; 17(12): 1271–1280. Published online 2021 Nov 19. doi: 10.1038/s41589-021-00907-2

PMCID:: PMC8607797

Abstract Article PDF–2.2M

Select item 855290716.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 854654417.

Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa

mBio. 2021 Sep-Oct; 12(5): e02299-21. Published online 2021 Sep 21. doi: 10.1128/mBio.02299-21

PMCID:: PMC8546544

Abstract Article PDF–6.5M

Select item 851760518.

HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

Nina H. Pipalia, Syed Z. Saad, Kanagaraj Subramanian, Abigail Cross, Aisha al-Motawa, Kunal Garg, Brian S.J. Blagg, Len Neckers, Paul Helquist, Olaf Wiest, Daniel S. Ory, Frederick R. Maxfield

J Lipid Res. 2021; 62: 100114. Published online 2021 Sep 3. doi: 10.1016/j.jlr.2021.100114

PMCID:: PMC8517605

Abstract Article PDF–3.4M

Select item 844631119.

Hepatocellular Carcinoma as a complication of Niemann-Pick disease type C1

Jorge L. Rodriguez-Gil, Simona E. Bianconi, Nicole Farhat, David E. Kleiner, Marie Nelson, Forbes D. Porter

Am J Med Genet A. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Am J Med Genet A. 2021 Oct; 185(10): 3111–3117. Published online 2021 Jun 17. doi: 10.1002/ajmg.a.62382

PMCID:: PMC8446311

Abstract Article PDF–832K

Select item 838259420.

Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target

Isabel García-Dorival, Miguel Ángel Cuesta-Geijo, Lucía Barrado-Gil, Inmaculada Galindo, Urtzi Garaigorta, Jesús Urquiza, Ana del Puerto, Nuria E. Campillo, Ana Martínez, Pablo Gastaminza, Carmen Gil, Covadonga Alonso

Antiviral Res. 2021 Oct; 194: 105167. Published online 2021 Aug 24. doi: 10.1016/j.antiviral.2021.105167

PMCID:: PMC8382594

Abstract Article PDF–3.8M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 146

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity