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Select item 112828591.

MARCH1 negatively regulates TBK1-mTOR signaling pathway by ubiquitinating TBK1

Xiao Li, Kai Cheng, Meng-Di Shang, Yong Yang, Bin Hu, Xi Wang, Xiao-Dan Wei, Yan-Chun Han, Xiao-Gang Zhang, Meng-Hua Dong, Zhen-Lin Yang, Jiu-Qiang Wang

BMC Cancer. 2024; 24: 902. Published online 2024 Jul 26. doi: 10.1186/s12885-024-12667-y

PMCID:: PMC11282859

Abstract Article PDF–3.9M

Select item 89419132.

The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels

Madison Martin, Praneet Sandhu, Rinki Kumar, Nicholas J. Buchkovich

J Virol. 2022 Mar; 96(6): e01806-21. Prepublished online 2022 Jan 19. Published online 2022 Mar 23. doi: 10.1128/jvi.01806-21

PMCID:: PMC8941913

Abstract Article PDF–3.5M

Select item 84818183.

Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism

Yu Bai, Ke Mo, Guirong Wang, Wanling Chen, Wei Zhang, Yibo Guo, Zhirong Sun

Front Pharmacol. 2021; 12: 710722. Published online 2021 Sep 16. doi: 10.3389/fphar.2021.710722

PMCID:: PMC8481818

Abstract Article PDF–3.6M

Select item 83526404.

E3 Ubiquitin Ligase March1 Facilitates OX40L Expression in Allergen-Stimulated Dendritic Cells Through Mediating the Ubiquitination of HDAC11

Xinxing Zhang, Zhichao Sun, Suyu Guo, Jiahui Zhang, Wenjing Gu, Zhengrong Chen, Li Huang

J Asthma Allergy. 2021; 14: 955–966. Published online 2021 Aug 5. doi: 10.2147/JAA.S318104

PMCID:: PMC8352640

Abstract Article PDF–7.7M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78945476.

5‐FU inhibits migration and invasion of CRC cells through PI3K/AKT pathway regulated by MARCH1

Nuan Wang, Lijuan Yang, Juanjuan Dai, Yan Wu, Ranran Zhang, Xingfang Jia, Chengxia Liu

Cell Biol Int. 2021 Feb; 45(2): 368–381. Published online 2020 Oct 29. doi: 10.1002/cbin.11493

PMCID:: PMC7894547

Abstract Article PDF–8.2M

Select item 73682867.

The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation

Jian Wu, Lu Xia, Xiangyu Yao, Xiao Yu, Keyla C. Tumas, Wenxiang Sun, Yang Cheng, Xiao He, Yu-chih Peng, Brajesh K. Singh, Cui Zhang, Chen-Feng Qi, Silvia Bolland, Sonja M. Best, Channe Gowda, Ruili Huang, Timothy G. Myers, Carole A. Long, Rong-Fu Wang, Xin-zhuan Su

Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16567–16578. Published online 2020 Jun 30. doi: 10.1073/pnas.2004332117

PMCID:: PMC7368286

Abstract Article PDF–2.4M

Select item 69328798.

ciRs-6 upregulates March1 to suppress bladder cancer growth by sponging miR-653

Yinjie Su, Weilian Feng, Guanglei Zhong, Yiyao Ya, Zehu Du, Juanyi Shi, Luping Chen, Wen Dong, Tianxin Lin

Aging (Albany NY) 2019 Dec 15; 11(23): 11202–11223. Published online 2019 Dec 10. doi: 10.18632/aging.102525

Correction in:: Aging (Albany NY). 2020 Mar 15; 12(5): 4678–4679.

PMCID:: PMC6932879

Abstract Article PDF–3.3M

Select item 65512669.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Abstract Article PDF–3.4M

Select item 648433610.

MARCH1 encourages tumour progression of hepatocellular carcinoma via regulation of PI3K‐AKT‐β‐catenin pathways

Lulu Xie, Hanhan Dai, Minjing Li, Wei Yang, Guohua Yu, Xia Wang, Peiyuan Wang, Wei Liu, Xuemei Hu, Mingdong Zhao

J Cell Mol Med. 2019 May; 23(5): 3386–3401. Published online 2019 Feb 22. doi: 10.1111/jcmm.14235

PMCID:: PMC6484336

Abstract Article PDF–2.6M

Select item 641643211.

Membrane-associated RING-CH (MARCH) 1 and 2 are MARCH family members that inhibit HIV-1 infection

Yanzhao Zhang, Takuya Tada, Seiya Ozono, Weitong Yao, Michiko Tanaka, Shoji Yamaoka, Satoshi Kishigami, Hideaki Fujita, Kenzo Tokunaga

J Biol Chem. 2019 Mar 8; 294(10): 3397–3405. Published online 2019 Jan 10. doi: 10.1074/jbc.AC118.005907

PMCID:: PMC6416432

Abstract Article PDF–2.1M

Select item 620019912.

The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner

Candida Bhagwandin, Erin L. Ashbeck, Michael Whalen, Joanna Bandola-Simon, Paul A. Roche, Adam Szajman, Sarah Mai Truong, Betsy C. Wertheim, Yann C. Klimentidis, Satoshi Ishido, Benjamin J. Renquist, Lonnie Lybarger

PLoS One. 2018; 13(10): e0204898. Published online 2018 Oct 24. doi: 10.1371/journal.pone.0204898

PMCID:: PMC6200199

Abstract Article PDF–1.5M

Select item 586825313.

A major isoform of the E3 ubiquitin ligase March-I in antigen-presenting cells has regulatory sequences within its gene

Sunil Kaul, Sharad K. Mittal, Paul A. Roche

J Biol Chem. 2018 Mar 23; 293(12): 4478–4485. Published online 2018 Jan 29. doi: 10.1074/jbc.RA118.001775

PMCID:: PMC5868253

Abstract Article PDF–1.1M

Select item 585798914.

Ubiquitin-conjugating enzyme E2 D1 (Ube2D1) mediates lysine-independent ubiquitination of the E3 ubiquitin ligase March-I

Lei Lei, Joanna Bandola-Simon, Paul A. Roche

J Biol Chem. 2018 Mar 16; 293(11): 3904–3912. Published online 2018 Feb 1. doi: 10.1074/jbc.RA117.001322

PMCID:: PMC5857989

Abstract Article PDF–1.5M

Select item 549522515.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 505521016.

Silencing MARCH1 suppresses proliferation, migration and invasion of ovarian cancer SKOV3 cells via downregulation of NF-κB and Wnt/β-catenin pathways

Ying Meng, Jianguo Hu, Yuhong Chen, Tinghe Yu, Lina Hu

Oncol Rep. 2016 Nov; 36(5): 2463–2470. Published online 2016 Sep 8. doi: 10.3892/or.2016.5076

PMCID:: PMC5055210

Abstract Article PDF–968K

Select item 501366617.

MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels

Arvindhan Nagarajan, Max C. Petersen, Ali R. Nasiri, Gina Butrico, Annie Fung, Hai-Bin Ruan, Romy Kursawe, Sonia Caprio, Jacques Thibodeau, Marie-Claude Bourgeois-Daigneault, Lisha Sun, Guangping Gao, Sanjay Bhanot, Michael J. Jurczak, Michael R. Green, Gerald I. Shulman, Narendra Wajapeyee

Nat Commun. 2016; 7: 12639. Published online 2016 Aug 31. doi: 10.1038/ncomms12639

PMCID:: PMC5013666

Abstract Article PDF–3.0M

Select item 411606018.

Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis

Matthias Olden, Tanguy Corre, Caroline Hayward, Daniela Toniolo, Sheila Ulivi, Paolo Gasparini, Giorgio Pistis, Shih-Jen Hwang, Sven Bergmann, Harry Campbell, Massimiliano Cocca, Ilaria Gandin, Giorgia Girotto, Bob Glaudemans, Nicholas D. Hastie, Johannes Loffing, Ozren Polasek, Luca Rampoldi, Igor Rudan, Cinzia Sala, Michela Traglia, Peter Vollenweider, Dragana Vuckovic, Sonia Youhanna, Julien Weber, Alan F. Wright, Zoltán Kutalik, Murielle Bochud, Caroline S. Fox, Olivier Devuyst

J Am Soc Nephrol. 2014 Aug; 25(8): 1869–1882. Published online 2014 Feb 27. doi: 10.1681/ASN.2013070781

PMCID:: PMC4116060

Abstract Article

Select item 358510119.

Ubiquitination by the Membrane-associated RING-CH-8 (MARCH-8) Ligase Controls Steady-state Cell Surface Expression of Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL) Receptor 1

Bert van de Kooij, Inge Verbrugge, Evert de Vries, Merel Gijsen, Veronica Montserrat, Chiel Maas, Jacques Neefjes, Jannie Borst

J Biol Chem. 2013 Mar 1; 288(9): 6617–6628. Published online 2013 Jan 8. doi: 10.1074/jbc.M112.448209

PMCID:: PMC3585101

Abstract Article PDF–2.0M

Select item 319946420.

Ubiquitin-mediated Regulation of CD86 Protein Expression by the Ubiquitin Ligase Membrane-associated RING-CH-1 (MARCH1)

Kathleen Corcoran, Maurice Jabbour, Candida Bhagwandin, Martin J. Deymier, Debra L. Theisen, Lonnie Lybarger

J Biol Chem. 2011 Oct 28; 286(43): 37168–37180. Published online 2011 Sep 6. doi: 10.1074/jbc.M110.204040

PMCID:: PMC3199464

Abstract Article PDF–2.2M

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