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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104928422.

NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development

Romana Bohuslavova, Valeria Fabriciova, Ondrej Smolik, Laura Lebrón-Mora, Pavel Abaffy, Sarka Benesova, Daniel Zucha, Lukas Valihrach, Zuzana Berkova, Frantisek Saudek, Gabriela Pavlinkova

Nat Commun. 2023; 14: 5554. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41306-6

PMCID:: PMC10492842

Abstract Article PDF–15M

Select item 90145593.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 88061054.

Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance

Jun Li, Jinshu Xu, Huihui Jiang, Ting Zhang, Aarthi Ramakrishnan, Li Shen, Pin-Xian Xu

J Am Soc Nephrol. 2021 Nov; 32(11): 2815–2833. Published online 2021 Nov. doi: 10.1681/ASN.2021040525

PMCID:: PMC8806105

Abstract Article

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80000266.

Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm

Jinshu Xu, Jun Li, Ting Zhang, Huihui Jiang, Aarthi Ramakrishnan, Bernd Fritzsch, Li Shen, Pin-Xian Xu

Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12): e2025196118. Published online 2021 Mar 15. doi: 10.1073/pnas.2025196118

PMCID:: PMC8000026

Abstract Article PDF–3.6M

Select item 75200147.

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation

Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman

Dev Biol. Author manuscript; available in PMC 2020 Sep 27.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008

PMCID:: PMC7520014

Abstract Article PDF–2.6M

Select item 66927708.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 60941259.

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation

Jian Sima, Zhijiang Yan, Yaohui Chen, Elin Lehrmann, Yongqing Zhang, Ramaiah Nagaraja, Weidong Wang, Zhong Wang, David Schlessinger

Proc Natl Acad Sci U S A. 2018 Aug 7; 115(32): 8173–8178. Published online 2018 Jul 23. doi: 10.1073/pnas.1800930115

PMCID:: PMC6094125

Abstract Article PDF–1.5M

Select item 588528310.

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes

Maximilian Witzel, Daniel Petersheim, Yanxin Fan, Ehsan Bahrami, Tomas Racek, Meino Rohlfs, Jacek Puchalka, Christian Mertes, Julien Gagneur, Christoph Ziegenhain, Wolfgang Enard, Asbjørg Stray-Pedersen, Peter D Arkwright, Miguel R Abboud, Vahid Pazhakh, Graham J Lieschke, Peter M Krawitz, Maik Dahlhoff, Marlon R Schneider, Eckhard Wolf, Hans-Peter Horny, Heinrich Schmidt, Alejandro A Schäffer, Christoph Klein

Nat Genet. Author manuscript; available in PMC 2018 Apr 5.

Published in final edited form as: Nat Genet. 2017 May; 49(5): 742–752. Published online 2017 Apr 3. doi: 10.1038/ng.3833

PMCID:: PMC5885283

Abstract Article PDF–2.8M

Select item 552085211.

Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening

Shuyi Ji, Linying Zhu, Yimeng Gao, Xiaoran Zhang, Yupeng Yan, Jin Cen, Rongxia Li, Rong Zeng, Lujian Liao, Chunhui Hou, Yawei Gao, Shaorong Gao, Gang Wei, Lijian Hui

Cell Res. 2017 May; 27(5): 642–656. Published online 2017 Mar 17. doi: 10.1038/cr.2017.36

PMCID:: PMC5520852

Abstract Article PDF–7.6M

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 492482613.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Ronghui Li, Qiping Dong, Xinni Yuan, Xin Zeng, Yu Gao, Cassandra Chiao, Hongda Li, Xinyu Zhao, Sunduz Keles, Zefeng Wang, Qiang Chang

PLoS Genet. 2016 Jun; 12(6): e1006129. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006129

PMCID:: PMC4924826

Abstract Article PDF–1.9M

Select item 464663714.

SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance

V. Adam Cruickshank, Patrycja Sroczynska, Aditya Sankar, Satoru Miyagi, Carsten Friis Rundsten, Jens Vilstrup Johansen, Kristian Helin

PLoS One. 2015; 10(11): e0142806. Published online 2015 Nov 16. doi: 10.1371/journal.pone.0142806

PMCID:: PMC4646637

Abstract Article PDF–1.2M

Select item 451183315.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga

Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859

PMCID:: PMC4511833

Abstract Article PDF–2.2M

Select item 433152916.

miR-30 Family microRNAs Regulate Myogenic Differentiation and Provide Negative Feedback on the microRNA Pathway

Martin G. Guess, Kristen K. B. Barthel, Brooke C. Harrison, Leslie A. Leinwand

PLoS One. 2015; 10(2): e0118229. Published online 2015 Feb 17. doi: 10.1371/journal.pone.0118229

PMCID:: PMC4331529

Abstract Article PDF–2.2M

Select item 415757717.

Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin

Andreas Kakarougkas, Amani Ismail, Anna L. Chambers, Enriqueta Riballo, Alex D. Herbert, Julia Künzel, Markus Löbrich, Penny A. Jeggo, Jessica A. Downs

Mol Cell. 2014 Sep 4; 55(5): 723–732. doi: 10.1016/j.molcel.2014.06.028

PMCID:: PMC4157577

Abstract Article

Select item 396495518.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 395066719.

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation

Ajeet Pratap Singh, Trevor K. Archer

Nucleic Acids Res. 2014 Mar; 42(5): 2958–2975. Published online 2013 Dec 13. doi: 10.1093/nar/gkt1232

PMCID:: PMC3950667

Abstract Article PDF–4.6M

Select item 366879320.

mSWI/SNF (BAF) Complexes Facilitate Decatentation of DNA by Topoisomerase IIa

Emily C. Dykhuizen, Diana C. Hargreaves, Erik Miller, Kairong Cui, Andrey Korshunov, Marcel Kool, Stefan Pfister, Yoon-Jae Cho, Keji Zhao, Gerald R. Crabtree

Nature. Author manuscript; available in PMC 2013 Nov 30.

Published in final edited form as: Nature. 2013 May 30; 497(7451): 624–627. Published online 2013 May 22. doi: 10.1038/nature12146

PMCID:: PMC3668793

Abstract Article PDF–1.6M

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