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Items: 1 to 20 of 60

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2
Marzia Indrigo, Ilaria Morella, Daniel Orellana, Raffaele d'Isa, Alessandro Papale, Riccardo Parra, Antonia Gurgone, Daniela Lecca, Anna Cavaccini, Cezar M Tigaret, Alfredo Cagnotto, Kimberley Jones, Simon Brooks, Gian Michele Ratto, Nicholas D Allen, Mariah J Lelos, Silvia Middei, Maurizio Giustetto, Anna R Carta, Raffaella Tonini, Mario Salmona, Jeremy Hall, Kerrie Thomas, Riccardo Brambilla, Stefania Fasano
EMBO Mol Med. 2023 Nov; 15(11): e15984. Published online 2023 Oct 4. doi: 10.15252/emmm.202215984
PMCID:
PMC10630888
AbstractArticlePDF–4.2M
3.
Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors
Paula Navarrete-López, María Maroto, Eva Pericuesta, Raúl Fernández-González, Marta Lombó, Priscila Ramos-Ibeas, Alfonso Gutiérrez-Adán
iScience. 2023 Jul 21; 26(7): 107134. Published online 2023 Jun 16. doi: 10.1016/j.isci.2023.107134
PMCID:
PMC10338237
AbstractArticlePDF–6.9M
4.
Karyopherin α deficiency contributes to human preimplantation embryo arrest
Wenjing Wang, Yoichi Miyamoto, Biaobang Chen, Juanzi Shi, Feiyang Diao, Wei Zheng, Qun Li, Lan Yu, Lin Li, Yao Xu, Ling Wu, Xiaoyan Mao, Jing Fu, Bin Li, Zheng Yan, Rong Shi, Xia Xue, Jian Mu, Zhihua Zhang, Tianyu Wu, Lin Zhao, Weijie Wang, Zhou Zhou, Jie Dong, Qiaoli Li, Li Jin, Lin He, Xiaoxi Sun, Ge Lin, Yanping Kuang, Lei Wang, Qing Sang
J Clin Invest. 2023 Jan 17; 133(2): e159951. Published online 2023 Jan 17. doi: 10.1172/JCI159951
PMCID:
PMC9843055
AbstractArticlePDF–2.0M
5.
KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation
Yujie Jia, Qi Wang, Minglu Liang, Kai Huang
J Transl Med. 2022; 20: 627. Published online 2022 Dec 28. doi: 10.1186/s12967-022-03841-6
PMCID:
PMC9798605
AbstractArticlePDF–8.8M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication
Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Cell Discov. 2021; 7: 37. Published online 2021 May 24. doi: 10.1038/s41421-021-00279-w
Correction in:
Cell Discov. 2021; 7: 58.
PMCID:
PMC8143069
AbstractArticlePDF–3.5M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism
Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell
iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132
PMCID:
PMC7236060
AbstractArticlePDF–6.1M
10.
USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2
Zeng Cai, Meng-Xin Zhang, Zhen Tang, Qiang Zhang, Jing Ye, Tian-Chen Xiong, Zhi-Dong Zhang, Bo Zhong
J Exp Med. 2020 May 4; 217(5): e20191174. Published online 2020 Mar 4. doi: 10.1084/jem.20191174
PMCID:
PMC7201923
AbstractArticlePDF–8.0M
11.
NLRP3 negatively regulates Treg differentiation through Kpna2-mediated nuclear translocation
Su-Ho Park, Sunyoung Ham, Arim Lee, Andreas Möller, Tae Sung Kim
J Biol Chem. 2019 Nov 22; 294(47): 17951–17961. Published online 2019 Oct 9. doi: 10.1074/jbc.RA119.010545
PMCID:
PMC6879348
AbstractArticlePDF–3.0M
12.
ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation
Yan Rong, Shu-Yan Ji, Ye-Zhang Zhu, Yun-Wen Wu, Li Shen, Heng-Yu Fan
Nucleic Acids Res. 2019 Dec 2; 47(21): 11387–11402. Published online 2019 Oct 10. doi: 10.1093/nar/gkz863
PMCID:
PMC6868374
AbstractArticlePDF–6.8M
13.
Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice
Satoshi Okano, Akira Yasui, Shin-ichiro Kanno, Kennichi Satoh, Masahiko Igarashi, Osamu Nakajima
J Diabetes Res. 2019; 2019: 7234549. Published online 2019 Apr 24. doi: 10.1155/2019/7234549
PMCID:
PMC6507265
AbstractArticlePDF–12M
14.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
15.
Repression of interstitial identity in nephron progenitor cells by Pax2 establishes the nephron-interstitium boundary throughout kidney development
Natalie Naiman, Kaoru Fujioka, Mari Fujino, M. Todd Valerius, S. Steven Potter, Andrew P. McMahon, Akio Kobayashi
Dev Cell. Author manuscript; available in PMC 2018 May 22.
Published in final edited form as: Dev Cell. 2017 May 22; 41(4): 349–365.e3. doi: 10.1016/j.devcel.2017.04.022
PMCID:
PMC5532731
AbstractArticlePDF–1.9M
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
17.
Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import
Hyo-Jung Choo, Alicia Cutler, Franziska Rother, Michael Bader, Grace K. Pavlath
Stem Cells. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Stem Cells. 2016 Nov; 34(11): 2784–2797. Published online 2016 Aug 1. doi: 10.1002/stem.2467
PMCID:
PMC5247404
AbstractArticlePDF–2.2M
18.
Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3
Joon Kyu Park, Tanuza Das, Eun Joo Song, Eunice EunKyeong Kim
Nucleic Acids Res. 2016 Jun 20; 44(11): 5424–5437. Published online 2016 Apr 7. doi: 10.1093/nar/gkw218
PMCID:
PMC4914101
AbstractArticlePDF–7.7M
19.
MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation
Yuntao Lu, Limin Xiao, Yawei Liu, Hai Wang, Hong Li, Qiang Zhou, Jun Pan, Bingxi Lei, Annie Huang, Songtao Qi
Autophagy. 2015 Dec; 11(12): 2213–2232. Published online 2015 Nov 9. doi: 10.1080/15548627.2015.1108507
Correction in:
Autophagy. 2016 Feb; 12(2): 445–448.
Correction in:
Autophagy. 2019; 15(6): 1125–1127.
PMCID:
PMC4835194
AbstractArticlePDF–2.9M
20.
Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling
Sumitra Miriyala, Chadinee Thippakorn, Luksana Chaiswing, Yong Xu, Teresa Noel, Artak Tovmasyan, Ines Batinic-Haberle, Craig W. Vander Kooi, Wang Chi, Ahmed Abdel Latif, Manikandan Panchatcharam, Virapong Prachayasittikul, D. Allan Butterfield, Mary Vore, Jeffrey Moscow, Daret K. St. Clair
Free Radic Biol Med. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2016 Feb; 91: 68–80. Published online 2015 Dec 9. doi: 10.1016/j.freeradbiomed.2015.12.002
PMCID:
PMC4761499
AbstractArticlePDF–2.4M

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