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Items: 1 to 20 of 42

1.
Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
Jose Luis Herrera, Masanobu Komatsu
Cell Rep. Author manuscript; available in PMC 2024 Apr 28.
Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113837. Published online 2024 Feb 24. doi: 10.1016/j.celrep.2024.113837
PMCID:
PMC11056028
AbstractArticlePDF–4.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Proteomics Analysis of R-Ras Deficiency in Oxygen Induced Retinopathy
Maria Vähätupa, Janika Nättinen, Ulla Aapola, Hannele Uusitalo-Järvinen, Hannu Uusitalo, Tero A. H. Järvinen
Int J Mol Sci. 2023 May; 24(9): 7914. Published online 2023 Apr 26. doi: 10.3390/ijms24097914
PMCID:
PMC10178533
AbstractArticlePDF–2.1M
4.
R-Ras1 and R-Ras2 Expression in Anatomical Regions and Cell Types of the Central Nervous System
Gonzalo Garcia-Martin, Miriam Sanz-Rodriguez, Berta Alcover-Sanchez, Marta P. Pereira, Francisco Wandosell, Beatriz Cubelos
Int J Mol Sci. 2022 Jan; 23(2): 978. Published online 2022 Jan 17. doi: 10.3390/ijms23020978
PMCID:
PMC8781598
AbstractArticlePDF–3.7M
5.
R-Ras deficiency in pericytes causes frequent microphthalmia and perturbs retinal vascular development
Jose Luis Herrera, Masanobu Komatsu
J Vasc Res. Author manuscript; available in PMC 2022 Apr 19.
Published in final edited form as: J Vasc Res. 2021; 58(4): 252–266. Published online 2021 Apr 19. doi: 10.1159/000514555
PMCID:
PMC8263468
AbstractArticlePDF–3.1M
6.
Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling
P. D. Arora, K. Nakajima, A. Nanda, A. Plaha, A. Wilde, D. B. Sacks, C. A. McCulloch
Mol Biol Cell. 2020 Jul 15; 31(15): 1595–1610. doi: 10.1091/mbc.E19-10-0554
PMCID:
PMC7521798
AbstractArticlePDF–4.7M
7.
Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery Disease
Xiaochao Wei, Sangeeta Adak, Mohamed Zayed, Li Yin, Chu Feng, Sarah L. Speck, Rahul S. Kathayat, Qiang Zhang, Bryan C. Dickinson, Clay F. Semenkovich
Circ Res. Author manuscript; available in PMC 2021 Jul 3.
Published in final edited form as: Circ Res. 2020 Jul 3; 127(2): 249–265. Published online 2020 Apr 1. doi: 10.1161/CIRCRESAHA.120.316752
PMCID:
PMC7334103
AbstractArticlePDF–3.2M
8.
R-Ras1 and R-Ras2 Are Essential for Oligodendrocyte Differentiation and Survival for Correct Myelination in the Central Nervous System
Miriam Sanz-Rodriguez, Agnès Gruart, Juan Escudero-Ramirez, Fernando de Castro, José María Delgado-García, Francisco Wandosell, Beatriz Cubelos
J Neurosci. 2018 May 30; 38(22): 5096–5110. doi: 10.1523/JNEUROSCI.3364-17.2018
PMCID:
PMC6705947
AbstractArticlePDF–5.6M
9.
The leucine-rich region of Flightless I interacts with R-ras to regulate cell extension formation
P. D. Arora, T. He, K. Ng, C. A. McCulloch
Mol Biol Cell. 2018 Oct 1; 29(20): 2481–2493. doi: 10.1091/mbc.E18-03-0147
PMCID:
PMC6233052
AbstractArticlePDF–2.1M
10.
R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature
Fangfei Li, Junko Sawada, Masanobu Komatsu
Nat Commun. 2017; 8: 1720. Published online 2017 Nov 23. doi: 10.1038/s41467-017-01865-x
PMCID:
PMC5700916
AbstractArticlePDF–4.9M
11.
R‐Ras deficiency does not affect papain‐induced IgE production in mice
Laura Kummola, Zsuzsanna Ortutay, Maria Vähätupa, Stuart Prince, Hannele Uusitalo‐Järvinen, Tero A.H. Järvinen, Ilkka S. Junttila
Immun Inflamm Dis. 2017 Sep; 5(3): 280–288. Published online 2017 May 11. doi: 10.1002/iid3.168
PMCID:
PMC5569372
AbstractArticlePDF–554K
12.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
13.
Lack of R-Ras Leads to Increased Vascular Permeability in Ischemic Retinopathy
Maria Vähätupa, Stuart Prince, Suvi Vataja, Teija Mertimo, Marko Kataja, Kati Kinnunen, Varpu Marjomäki, Hannu Uusitalo, Masanobu Komatsu, Tero A.H. Järvinen, Hannele Uusitalo–Järvinen
Invest Ophthalmol Vis Sci. 2016 Sep; 57(11): 4898–4909. Published online 2016 Sep 19. doi: 10.1167/iovs.16-19212
PMCID:
PMC5032915
AbstractArticlePDF–1.5M
14.
R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding
Xiaocai Yan, Mingfei Yan, Yihe Guo, Gobind Singh, Yuhong Chen, Mei Yu, Demin Wang, Cheryl A. Hillery, Andrew M. Chan
PLoS One. 2015; 10(12): e0145218. Published online 2015 Dec 28. doi: 10.1371/journal.pone.0145218
PMCID:
PMC4692399
AbstractArticlePDF–8.7M
15.
Resistance of R-Ras knockout mice to skin tumour induction
Ulrike May, Stuart Prince, Maria Vähätupa, Anni M. Laitinen, Katriina Nieminen, Hannele Uusitalo-Järvinen, Tero A. H. Järvinen
Sci Rep. 2015; 5: 11663. Published online 2015 Jul 2. doi: 10.1038/srep11663
PMCID:
PMC4488886
AbstractArticlePDF–2.3M
16.
R-Ras Protein Inhibits Autophosphorylation of Vascular Endothelial Growth Factor Receptor 2 in Endothelial Cells and Suppresses Receptor Activation in Tumor Vasculature
Junko Sawada, Fangfei Li, Masanobu Komatsu
J Biol Chem. 2015 Mar 27; 290(13): 8133–8145. Published online 2015 Feb 2. doi: 10.1074/jbc.M114.591511
PMCID:
PMC4375470
AbstractArticlePDF–3.1M
17.
R-Ras Contributes to LTP and Contextual Discrimination
Michael J. Darcy, Shan-Xue Jin, Larry A. Feig
Neuroscience. Author manuscript; available in PMC 2015 Sep 26.
Published in final edited form as: Neuroscience. 2014 Sep 26; 277: 334–342. Published online 2014 Jul 17. doi: 10.1016/j.neuroscience.2014.07.010
PMCID:
PMC4164585
AbstractArticlePDF–784K
18.
An Increase in Tolerogenic Dendritic Cell and Natural T Regulatory Cell Numbers During EAE in Rras−/− Mice Results in Attenuated Disease
Avijit Ray, Sreemanti Basu, Nichole M. Miller, Andrew M. Chan, Bonnie N. Dittel
J Immunol. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: J Immunol. 2014 Jun 1; 192(11): 5109–5117. Published online 2014 Apr 25. doi: 10.4049/jimmunol.1302254
PMCID:
PMC4041102
AbstractArticlePDF–762K
19.
Genetic dissection of plexin signaling in vivo
Thomas Worzfeld, Jakub M. Swiercz, Aycan Sentürk, Berit Genz, Alexander Korostylev, Suhua Deng, Jingjing Xia, Mikio Hoshino, Jonathan A. Epstein, Andrew M. Chan, Brigitte Vollmar, Amparo Acker-Palmer, Rohini Kuner, Stefan Offermanns
Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6): 2194–2199. Published online 2014 Jan 27. doi: 10.1073/pnas.1308418111
PMCID:
PMC3926053
AbstractArticlePDF–1.3M
20.
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma through derepression of DUSP1 phosphatase and inhibition of ERK
Antonio Maraver, Pablo J. Fernández-Marcos, Daniel Herranz, Maribel Muñoz-Martin, Gonzalo Gomez-Lopez, Marta Cañamero, Francisca Mulero, Diego Megías, Marta Sanchez-Carbayo, Jie Shen, Montserrat Sanchez-Cespedes, Teresa Palomero, Adolfo Ferrando, Manuel Serrano
Cancer Cell. Author manuscript; available in PMC 2013 Oct 31.
Published in final edited form as: Cancer Cell. 2012 Aug 14; 22(2): 10.1016/j.ccr.2012.06.014. doi: 10.1016/j.ccr.2012.06.014
PMCID:
PMC3813920
AbstractArticlePDF–4.7M

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