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Select item 105486861.

Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning

Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group

Genome Med. 2023; 15: 79. Published online 2023 Oct 4. doi: 10.1186/s13073-023-01233-z

PMCID:: PMC10548686

Abstract Article PDF–7.0M

Select item 103802802.

Potential Roles for the GluN2D NMDA Receptor Subunit in Schizophrenia

Chitra Vinnakota, Matthew R. Hudson, Nigel C. Jones, Suresh Sundram, Rachel A. Hill

Int J Mol Sci. 2023 Jul; 24(14): 11835. Published online 2023 Jul 23. doi: 10.3390/ijms241411835

PMCID:: PMC10380280

Abstract Article PDF–793K

Select item 97226273.

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs

Tsung-Han Chou, Hyunook Kang, Noriko Simorowski, Stephen F. Traynelis, Hiro Furukawa

Mol Cell. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Mol Cell. 2022 Dec 1; 82(23): 4548–4563.e4. Published online 2022 Oct 28. doi: 10.1016/j.molcel.2022.10.008

PMCID:: PMC9722627

Abstract Article PDF–3.3M

Select item 92626144.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 89206575.

MicroRNA-129-1-3p Represses the Progression of Triple-Negative Breast Cancer by Targeting the GRIN2D Gene

Qi Li, Zehui Gu, Qi Tan, Liqun Ren, Suxian Chen

Biomed Res Int. 2022; 2022: 1549357. Published online 2022 Mar 7. doi: 10.1155/2022/1549357

PMCID:: PMC8920657

Abstract Article PDF–1.3M

Select item 72720256.

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons

Jonathan Garst-Orozco, Ruchi Malik, Thomas A. Lanz, Mark L. Weber, Hualin Xi, Dominique Arion, John F. Enwright, III, David A. Lewis, Patricio O’Donnell, Vikaas S. Sohal, Derek L. Buhl

PLoS One. 2020; 15(6): e0233895. Published online 2020 Jun 4. doi: 10.1371/journal.pone.0233895

PMCID:: PMC7272025

Abstract Article PDF–1.6M

Select item 67824507.

Neuronal Interleukin-16 (NIL-16): A Dual Function PDZ Domain Protein

Cornelia Kurschner, Michisuke Yuzaki

J Neurosci. 1999 Sep 15; 19(18): 7770–7780. doi: 10.1523/JNEUROSCI.19-18-07770.1999

PMCID:: PMC6782450

Abstract Article PDF–604K

Select item 67297748.

NMDA Receptor GluRϵ/NR2 Subunits Are Essential for Postsynaptic Localization and Protein Stability of GluRζ1/NR1 Subunit

Manabu Abe, Masahiro Fukaya, Takeshi Yagi, Masayoshi Mishina, Masahiko Watanabe, Kenji Sakimura

J Neurosci. 2004 Aug 18; 24(33): 7292–7304. doi: 10.1523/JNEUROSCI.1261-04.2004

PMCID:: PMC6729774

Abstract Article PDF–1.3M

Select item 66716929.

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

Wenxue Li, Yan Huang, Rollie Reid, Joseph Steiner, Tanya Malpica-Llanos, Thomas A. Darden, Susarla K. Shankar, Anita Mahadevan, Parthasarthy Satishchandra, Avindra Nath

J Neurosci. 2008 Nov 19; 28(47): 12190–12198. doi: 10.1523/JNEUROSCI.3019-08.2008

Correction in:: J Neurosci. 2008 Dec 10; 28(50): np.

PMCID:: PMC6671692

Abstract Article PDF–618K

Select item 657873810.

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

S Akbarian, NJ Sucher, D Bradley, A Tafazzoli, D Trinh, WP Hetrick, SG Potkin, CA Sandman, WE Bunney, Jr, EG Jones

J Neurosci. 1996 Jan 1; 16(1): 19–30. doi: 10.1523/JNEUROSCI.16-01-00019.1996

PMCID:: PMC6578738

Abstract PDF–3.9M

Select item 580249611.

Rare loss of function mutations in N-methyl-d-aspartate glutamate receptors and their contributions to schizophrenia susceptibility

Yanjie Yu, Yingni Lin, Yuto Takasaki, Chenyao Wang, Hiroki Kimura, Jingrui Xing, Kanako Ishizuka, Miho Toyama, Itaru Kushima, Daisuke Mori, Yuko Arioka, Yota Uno, Tomoko Shiino, Yukako Nakamura, Takashi Okada, Mako Morikawa, Masashi Ikeda, Nakao Iwata, Yuko Okahisa, Manabu Takaki, Shinji Sakamoto, Toshiyuki Someya, Jun Egawa, Masahide Usami, Masaki Kodaira, Akira Yoshimi, Tomoko Oya-Ito, Branko Aleksic, Kinji Ohno, Norio Ozaki

Transl Psychiatry. 2018; 8: 12. Published online 2018 Jan 10. doi: 10.1038/s41398-017-0061-y

PMCID:: PMC5802496

Abstract Article PDF–694K

Select item 573763412.

Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS

Thangavel Samikkannu, Marisela Agudelo, Nimisha Gandhi, Pichili V. B. Reddy, Zainulabedin M. Saiyed, Donald Nwankwo, Madhavan P. N. Nair

J Neurovirol. Author manuscript; available in PMC 2017 Dec 20.

Published in final edited form as: J Neurovirol. 2011 Jun; 17(3): 230–238. Published online 2011 Apr 14. doi: 10.1007/s13365-011-0026-5

PMCID:: PMC5737634

Abstract Article PDF–553K

Select item 506565213.

GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers

Dong Li, Hongjie Yuan, Xilma R. Ortiz-Gonzalez, Eric D. Marsh, Lifeng Tian, Elizabeth M. McCormick, Gabrielle J. Kosobucki, Wenjuan Chen, Anthony J. Schulien, Rosetta Chiavacci, Anel Tankovic, Claudia Naase, Frieder Brueckner, Celina von Stülpnagel-Steinbeis, Chun Hu, Hirofumi Kusumoto, Ulrike B.S. Hedrich, Gina Elsen, Konstanze Hörtnagel, Elias Aizenman, Johannes R. Lemke, Hakon Hakonarson, Stephen F. Traynelis, Marni J. Falk

Am J Hum Genet. 2016 Oct 6; 99(4): 802–816. Published online 2016 Sep 8. doi: 10.1016/j.ajhg.2016.07.013

PMCID:: PMC5065652

Abstract Article PDF–2.9M

Select item 499146614.

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

Henry J.M. Ferguson, Joseph W. Wragg, Stephen Ward, Victoria L. Heath, Tariq Ismail, Roy Bicknell

Oncotarget. 2016 Apr 12; 7(15): 20440–20454. Published online 2016 Mar 1. doi: 10.18632/oncotarget.7812

PMCID:: PMC4991466

Abstract Article PDF–3.2M

Select item 489614715.

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine

Wesley N. Wayman, Lihua Chen, Amanda L. Persons, T. Celeste Napier

Curr HIV Res. Author manuscript; available in PMC 2016 Jun 7.

Published in final edited form as: Curr HIV Res. 2015; 13(1): 80–87. doi: 10.2174/0929867322666150311164504

PMCID:: PMC4896147

Abstract Article PDF–361K

Select item 484160716.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 455434517.

HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorders

Thangavel Samikkannu, Venkata S.R. Atluri, Adriana Y. Arias, Kesava V.K. Rao, Carmen T. Mulet, Rahul D. Jayant, Madhavan P.N. Nair

Curr HIV Res. Author manuscript; available in PMC 2015 Aug 31.

Published in final edited form as: Curr HIV Res. 2014; 12(6): 397–405. doi: 10.2174/1570162x13666150121104720

PMCID:: PMC4554345

Abstract Article PDF–1.5M

Select item 408904118.

Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport

Italo Mocchetti, Alessia Bachis, Valeriya Avdoshina

Neurotox Res. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: Neurotox Res. 2012 Jan; 21(1): 79–89. Published online 2011 Sep 27. doi: 10.1007/s12640-011-9279-2

PMCID:: PMC4089041

Abstract Article PDF–432K

Select item 404199019.

D1/NMDA Receptors and Concurrent Methamphetamine+ HIV-1 Tat Neurotoxicity

Michael Y. Aksenov, M. V. Aksenova, C. F. Mactutus, Rosemarie M. Booze

J Neuroimmune Pharmacol. Author manuscript; available in PMC 2014 Jun 3.

Published in final edited form as: J Neuroimmune Pharmacol. 2012 Sep; 7(3): 599–608. Published online 2012 May 3. doi: 10.1007/s11481-012-9362-3

PMCID:: PMC4041990

Abstract Article PDF–2.5M

Select item 398932920.

HIV-1 Tat-Mediated Apoptosis in Human Blood-Retinal Barrier-Associated Cells

Xin Che, Fanglin He, Yuan Deng, Shiqiong Xu, Xianqun Fan, Ping Gu, Zhiliang Wang

PLoS One. 2014; 9(4): e95420. Published online 2014 Apr 16. doi: 10.1371/journal.pone.0095420

PMCID:: PMC3989329

Abstract Article PDF–10M

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