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Items: 1 to 20 of 90

1.
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
Lidia Wrobel, Sandra M. Hill, Alvin Djajadikerta, Marian Fernandez-Estevez, Cansu Karabiyik, Avraham Ashkenazi, Victoria J. Barratt, Eleanna Stamatakou, Anders Gunnarsson, Timothy Rasmusson, Eric W. Miele, Nigel Beaton, Roland Bruderer, Yuehan Feng, Lukas Reiter, M. Paola Castaldi, Rebecca Jarvis, Keith Tan, Roland W. Bürli, David C. Rubinsztein
Nat Commun. 2022; 13: 4146. Published online 2022 Jul 16. doi: 10.1038/s41467-022-31905-0
PMCID:
PMC9288506
AbstractArticlePDF–3.9M
2.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
3.
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression
Xuan Li, Kai-Bin Yang, Wei Chen, Jia Mai, Xiao-Qi Wu, Ting Sun, Rui-Yan Wu, Lin Jiao, Dan-Dan Li, Jiao Ji, Hai-Liang Zhang, Yan Yu, Yu-Hong Chen, Gong-Kan Feng, Rong Deng, Jun-Dong Li, Xiao-Feng Zhu
Autophagy. 2021; 17(12): 4323–4340. Published online 2021 May 12. doi: 10.1080/15548627.2021.1912270
PMCID:
PMC8726624
AbstractArticlePDF–26M
4.
Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway
Lianguo Xue, Tao Jia, Yuanxin Zhu, Lidong Zhao, Jianping Mao
J Orthop Surg Res. 2021; 16: 723. Published online 2021 Dec 20. doi: 10.1186/s13018-021-02867-8
PMCID:
PMC8686392
AbstractArticlePDF–6.8M
5.
The deubiquitinase USP11 is a versatile and conserved regulator of autophagy
Mila Basic, Alexandra Hertel, Justyna Bajdzienko, Florian Bonn, Mariana Tellechea, Alexandra Stolz, Andreas Kern, Christian Behl, Anja Bremm
J Biol Chem. 2021 Nov; 297(5): 101263. Published online 2021 Sep 30. doi: 10.1016/j.jbc.2021.101263
PMCID:
PMC8546420
AbstractArticlePDF–2.4M
6.
ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis
Dongfang Li, Peter Vogel, Xiujie Li-Harms, Bo Wang, Mondira Kundu
Autophagy. 2021; 17(9): 2576–2585. Published online 2021 Apr 14. doi: 10.1080/15548627.2021.1911549
PMCID:
PMC8496527
AbstractArticlePDF–3.0M
7.
ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells
JaeYung Lee, Jiyea Kim, Jeongeun Shin, YongHyun Kang, Jungwon Choi, Heesun Cheong
Int J Mol Sci. 2021 Sep; 22(17): 9182. Published online 2021 Aug 25. doi: 10.3390/ijms22179182
PMCID:
PMC8430637
AbstractArticlePDF–4.8M
8.
SNAP47 Interacts with ATG14 to Promote VP1 Conjugation and CVB3 Propagation
Pinhao Xiang, Yasir Mohamud, Honglin Luo
Cells. 2021 Aug; 10(8): 2141. Published online 2021 Aug 20. doi: 10.3390/cells10082141
PMCID:
PMC8394894
AbstractArticlePDF–2.4M
9.
Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy
Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda
Autophagy. 2021; 17(8): 2011–2036. Published online 2021 Jan 26. doi: 10.1080/15548627.2021.1874133
PMCID:
PMC8386740
AbstractArticlePDF–13M
10.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I
Cefan Zhou, Xuehong Qian, Miao Hu, Rui Zhang, Nanxi Liu, Yuan Huang, Jing Yang, Juan Zhang, Hua Bai, Yuyan Yang, Yefu Wang, Declan Ali, Marek Michalak, Xing-Zhen Chen, Jingfeng Tang
Autophagy. 2020; 16(10): 1786–1806. Published online 2019 Nov 7. doi: 10.1080/15548627.2019.1687212
PMCID:
PMC8386619
AbstractArticlePDF–10M
11.
miR-424通过调控ATG14的表达抑制肝癌细胞的自噬和增殖
赵 梓丹, 黄 为, 和 君建, 冯 超
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jul 20; 41(7): 1012–1021. Chinese. doi: 10.12122/j.issn.1673-4254.2021.07.07
PMCID:
PMC8329672
AbstractArticlePDF–2.4M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang, Jing Xu, Hong Yang, Yuanchang Hu, Jiannan Qiu, Liyong Pu, Jinhai Tang, Xuehao Wang
Signal Transduct Target Ther. 2021; 6: 76. Published online 2021 Feb 23. doi: 10.1038/s41392-020-00453-8
PMCID:
PMC7900110
AbstractArticlePDF–7.0M
14.
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation
Guangyan Miao, Hongyu Zhao, Yan Li, Mingming Ji, Yong Chen, Yi Shi, Yuhai Bi, Peihui Wang, Hong Zhang
Dev Cell. 2021 Feb 22; 56(4): 427–442.e5. Published online 2020 Dec 16. doi: 10.1016/j.devcel.2020.12.010
PMCID:
PMC7832235
AbstractArticlePDF–5.9M
15.
Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker
EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948
PMCID:
PMC7737610
AbstractArticlePDF–3.7M
16.
Streptococcus pneumoniae promotes its own survival via choline-binding protein CbpC-mediated degradation of ATG14
Sayaka Shizukuishi, Michinaga Ogawa, Akihide Ryo, Makoto Ohnishi
Autophagy. 2020; 16(8): 1529–1531. Published online 2020 Jun 17. doi: 10.1080/15548627.2020.1776475
PMCID:
PMC7480810
AbstractArticlePDF–1.0M
17.
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3
Kejia Liu, Chu Guo, Yimin Lao, Jie Yang, Fei Chen, Yuzheng Zhao, Yi Yang, Jie Yang, Jing Yi
Autophagy. 2020; 16(6): 975–990. Published online 2019 Aug 2. doi: 10.1080/15548627.2019.1647944
PMCID:
PMC7469448
AbstractArticlePDF–6.2M
18.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes
Cefan Zhou, Changhua Yi, Yongxiang Yi, Wenying Qin, Yanan Yan, Xueying Dong, Xuewen Zhang, Yuan Huang, Rui Zhang, Jie Wei, Declan William Ali, Marek Michalak, Xing-Zhen Chen, Jingfeng Tang
Mol Cancer. 2020; 19: 118. Published online 2020 Jul 29. doi: 10.1186/s12943-020-01237-y
PMCID:
PMC7389684
AbstractArticlePDF–12M
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation
Byeong-Won Kim, Yunjung Jin, Jiyea Kim, Jun Hoe Kim, Juneyoung Jung, Seongman Kang, Ick Young Kim, Joungmok Kim, Heesun Cheong, Hyun Kyu Song
Autophagy. 2018; 14(12): 2104–2116. Published online 2018 Aug 16. doi: 10.1080/15548627.2018.1504716
PMCID:
PMC6984762
AbstractArticlePDF–2.0M

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