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Select item 111826721.

Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation

Ioanna Tiniakou, Pei-Feng Hsu, Lorena S. Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M. Adams, Geunhyo Jang, Chetna Soni, Colleen M. Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C. Rodrick, Drew Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T. Bedford, Stephen D. Nimer, Vesa Kaartinen, Esteban O. Mazzoni, Boris Reizis

Sci Immunol. Author manuscript; available in PMC 2024 Jun 17.

Published in final edited form as: Sci Immunol. 2024 Apr 12; 9(94): eadi1023. Published online 2024 Apr 12. doi: 10.1126/sciimmunol.adi1023

PMCID:: PMC11182672

Abstract Article PDF–3.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 93585853.

Downregulation of TRIM33 Promotes Survival and Epithelial–Mesenchymal Transition in Gastric Cancer

Fang Wang, Wenjun Wang, Xiaoting Wu, Cui Tang, Fang Du, Zhiguo Lu, Zhuoyang Zhang, Hui Xu, Xiangmei Cao, P. Andy Li

Technol Cancer Res Treat. 2022; 21: 15330338221114505. Published online 2022 Aug 5. doi: 10.1177/15330338221114505

PMCID:: PMC9358585

Abstract Article PDF–12M

Select item 93286804.

SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8⁺ T cell cytotoxic function

Xinwei Liu, Jing Hao, Peng Wei, Xiaohong Zhao, Qiuyan Lan, Lu Ni, Yongzhen Chen, Xue Bai, Ling Ni, Chen Dong

Sci Adv. 2022 Jul; 8(30): eabo4577. Published online 2022 Jul 27. doi: 10.1126/sciadv.abo4577

PMCID:: PMC9328680

Abstract Article PDF–3.4M

Select item 91618815.

The crystallin alpha B (HSPB5)-tripartite motif containing 33 (TRIM33) axis mediates myocardial fibrosis induced by angiotensinogen II through transforming growth factor-β (TGF-β1)-Smad3/4 signaling

Tianwen Wei, Yingqiang Du, Tiankai Shan, Jiawen Chen, Dongwei Shi, Tongtong Yang, Jiankang Wang, Jun Zhang, Yafei Li

Bioengineered. 2022; 13(4): 8836–8849. Published online 2022 Mar 25. doi: 10.1080/21655979.2022.2054913

PMCID:: PMC9161881

Abstract Article PDF–4.1M

Select item 82822706.

TRIM33 protects osteoblasts from oxidative stress‐induced apoptosis in osteoporosis by inhibiting FOXO3a ubiquitylation and degradation

De‐bo Zou, Zongyou Mou, Wenliang Wu, Haichun Liu

Aging Cell. 2021 Jul; 20(7): e13367. Published online 2021 Jun 8. doi: 10.1111/acel.13367

PMCID:: PMC8282270

Abstract Article PDF–1.8M

Select item 79711407.

Hepatic stellate cell–specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis

Eun Ju Lee, Injoo Hwang, Ji Yeon Lee, Jong Nam Park, Keun Cheon Kim, Irene Kim, Dodam Moon, Hyomin Park, Seo-Yeon Lee, Hong Sug Kim, Dae Won Jun, Sung-Hye Park, Hyo-Soo Kim

J Exp Med. 2020 Jun 1; 217(6): e20190402. Published online 2020 Apr 8. doi: 10.1084/jem.20190402

PMCID:: PMC7971140

Abstract Article PDF–6.5M

Select item 76413548.

A genetic variant controls interferon-β gene expression in human myeloid cells by preventing C/EBP-β binding on a conserved enhancer

Anaïs Assouvie, Maxime Rotival, Juliette Hamroune, Didier Busso, Paul-Henri Romeo, Lluis Quintana-Murci, Germain Rousselet

PLoS Genet. 2020 Nov; 16(11): e1009090. Published online 2020 Nov 4. doi: 10.1371/journal.pgen.1009090

PMCID:: PMC7641354

Abstract Article PDF–2.2M

Select item 73352059.

The induction and function of the anti-inflammatory fate of T_H17 cells

Hao Xu, Theodora Agalioti, Jun Zhao, Babett Steglich, Ramez Wahib, Maria Carolina Amezcua Vesely, Piotr Bielecki, Will Bailis, Ruaidhri Jackson, Daniel Perez, Jakob Izbicki, Paula Licona-Limón, Vesa Kaartinen, Jens Geginat, Enric Esplugues, Eva Tolosa, Samuel Huber, Richard A. Flavell, Nicola Gagliani

Nat Commun. 2020; 11: 3334. Published online 2020 Jul 3. doi: 10.1038/s41467-020-17097-5

PMCID:: PMC7335205

Abstract Article PDF–3.0M

Select item 692335810.

Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection

Mark J. McCarron, Magali Irla, Arnauld Sergé, Saidi M’Homa Soudja, Julien C. Marie

Nat Commun. 2019; 10: 5690. Published online 2019 Dec 19. doi: 10.1038/s41467-019-13456-z

PMCID:: PMC6923358

Abstract Article PDF–3.4M

Select item 689813011.

Trim33 (Tif1γ) is not required for skeletal muscle development or regeneration but suppresses cholecystokinin expression

Cassie A. Parks, Katherine Pak, Iago Pinal-Fernandez, Wilson Huang, Assia Derfoul, Andrew L. Mammen

Sci Rep. 2019; 9: 18507. Published online 2019 Dec 6. doi: 10.1038/s41598-019-54651-8

PMCID:: PMC6898130

Abstract Article PDF–1.1M

Select item 660476712.

TRIM33 deficiency in monocytes and macrophages impairs resolution of colonic inflammation

Vanessa Petit, Aude Parcelier, Cecile Mathé, Vilma Barroca, Claire Torres, Daniel Lewandowski, Federica Ferri, Anne-Sophie Gallouët, Marion Dalloz, Océane Dinet, Gilles Boschetti, Marie-Catherine Vozenin, Paul-Henri Roméo

EBioMedicine. 2019 Jun; 44: 60–70. Published online 2019 May 24. doi: 10.1016/j.ebiom.2019.05.037

PMCID:: PMC6604767

Abstract Article PDF–955K

Select item 654737213.

Trim33 is required for appropriate development of pre-cardiogenic mesoderm

Sudha Rajderkar, Jeffrey M. Mann, Christopher Panaretos, Kenji Yumoto, Hong-Dong Li, Yuji Mishina, Benjamin Ralston, Vesa Kaartinen

Dev Biol. Author manuscript; available in PMC 2020 Jun 15.

Published in final edited form as: Dev Biol. 2019 Jun 15; 450(2): 101–114. Published online 2019 Mar 30. doi: 10.1016/j.ydbio.2019.03.018

PMCID:: PMC6547372

Abstract Article PDF–3.9M

Select item 602851714.

Trim33 mediates the proinflammatory function of Th17 cells

Shinya Tanaka, Yu Jiang, Gustavo J. Martinez, Kentaro Tanaka, Xiaowei Yan, Tomohiro Kurosaki, Vesa Kaartinen, Xin-Hua Feng, Qiang Tian, Xiaohu Wang, Chen Dong

J Exp Med. 2018 Jul 2; 215(7): 1853–1868. doi: 10.1084/jem.20170779

PMCID:: PMC6028517

Abstract Article PDF–2.8M

Select item 535489615.

Macrophage production and activation are dependent on TRIM33

Anne-Sophie Gallouet, Federica Ferri, Vanessa Petit, Aude Parcelier, Daniel Lewandowski, Nathalie Gault, Vilma Barroca, Stéphanie Le Gras, Eric Soler, Frank Grosveld, Irwin Davidson, Paul-Henri Romeo

Oncotarget. 2017 Jan 17; 8(3): 5111–5122. Published online 2016 Dec 10. doi: 10.18632/oncotarget.13872

PMCID:: PMC5354896

Abstract Article PDF–4.3M

Select item 467382616.

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Federica Ferri, Aude Parcelier, Vanessa Petit, Anne-Sophie Gallouet, Daniel Lewandowski, Marion Dalloz, Anita van den Heuvel, Petros Kolovos, Eric Soler, Mario Leonardo Squadrito, Michele De Palma, Irwin Davidson, Germain Rousselet, Paul-Henri Romeo

Nat Commun. 2015; 6: 8900. Published online 2015 Nov 23. doi: 10.1038/ncomms9900