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Select item 109168661.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 89515562.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 87056933.

Roles of the Na⁺/H⁺ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion

Xiuju Li, Benjamin Buckley, Konstantin Stoletov, Yang Jing, Marie Ranson, John D. Lewis, Mike Kelso, Larry Fliegel

Int J Mol Sci. 2021 Dec; 22(24): 13263. Published online 2021 Dec 9. doi: 10.3390/ijms222413263

PMCID:: PMC8705693

Abstract Article PDF–5.0M

Select item 85838164.

Amino Acids 785, 787 of the Na⁺/H⁺ Exchanger Cytoplasmic Tail Modulate Protein Activity and Tail Conformation

Xiuju Li, Tommy Tu, Sicheng Quan, Francisco J. Quintero, Richard Fahlman, Larry Fliegel

Int J Mol Sci. 2021 Nov; 22(21): 11349. Published online 2021 Oct 21. doi: 10.3390/ijms222111349

PMCID:: PMC8583816

Abstract Article PDF–2.6M

Select item 85529075.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 85090386.

Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett’s Esophageal Cell Line

Eszter Becskeházi, Marietta Margaréta Korsós, Eleonóra Gál, László Tiszlavicz, Zsófia Hoyk, Mária A. Deli, Zoltán Márton Köhler, Anikó Keller-Pintér, Attila Horváth, Kata Csekő, Zsuzsanna Helyes, Péter Hegyi, Viktória Venglovecz

Int J Mol Sci. 2021 Oct; 22(19): 10581. Published online 2021 Sep 30. doi: 10.3390/ijms221910581

PMCID:: PMC8509038

Abstract Article PDF–2.3M

Select item 83916957.

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Estella A. Newcombe, Catarina B. Fernandes, Jeppe E. Lundsgaard, Inna Brakti, Kresten Lindorff-Larsen, Annette E. Langkilde, Karen Skriver, Birthe B. Kragelund

Biomolecules. 2021 Aug; 11(8): 1173. Published online 2021 Aug 9. doi: 10.3390/biom11081173

PMCID:: PMC8391695

Abstract Article PDF–1.2M

Select item 83217918.

Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells

Sagar S. Manoli, Kyle Kisor, Bradley A. Webb, Diane L. Barber

Am J Physiol Cell Physiol. 2021 Jul 1; 321(1): C147–C157. Published online 2021 May 26. doi: 10.1152/ajpcell.00001.2021

PMCID:: PMC8321791

Abstract Article

Select item 81998939.

Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species

Xiaoling Li, Gregor Römer, Raphaela P. Kerindongo, Jeroen Hermanides, Martin Albrecht, Markus W. Hollmann, Coert J. Zuurbier, Benedikt Preckel, Nina C. Weber

Int J Mol Sci. 2021 Jun; 22(11): 6044. Published online 2021 Jun 3. doi: 10.3390/ijms22116044

PMCID:: PMC8199893

Abstract Article PDF–1.7M

Select item 819028010.

Structure and mechanism of the human NHE1-CHP1 complex

Yanli Dong, Yiwei Gao, Alina Ilie, DuSik Kim, Annie Boucher, Bin Li, Xuejun C. Zhang, John Orlowski, Yan Zhao

Nat Commun. 2021; 12: 3474. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23496-z

PMCID:: PMC8190280

Abstract Article PDF–4.4M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800966412.

Dynamic Na⁺/H⁺ exchanger 1 (NHE1) – calmodulin complexes of varying stoichiometry and structure regulate Ca²⁺-dependent NHE1 activation

Lise M Sjøgaard-Frich, Andreas Prestel, Emilie S Pedersen, Marc Severin, Kristian Kølby Kristensen, Johan G Olsen, Birthe B Kragelund, Stine Falsig Pedersen

eLife. 2021; 10: e60889. Published online 2021 Mar 3. doi: 10.7554/eLife.60889

PMCID:: PMC8009664

Abstract Article PDF–5.7M

Select item 800018513.

Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

Benjamin J. Buckley, Ashna Kumar, Ashraf Aboelela, Richard S. Bujaroski, Xiuju Li, Hiwa Majed, Larry Fliegel, Marie Ranson, Michael J. Kelso

Int J Mol Sci. 2021 Mar; 22(6): 2999. Published online 2021 Mar 15. doi: 10.3390/ijms22062999

PMCID:: PMC8000185

Abstract Article PDF–2.4M

Select item 771338414.

The intracellular lipid-binding domain of human Na⁺/H⁺ exchanger 1 forms a lipid-protein co-structure essential for activity

Ruth Hendus-Altenburger, Jens Vogensen, Emilie Skotte Pedersen, Alessandra Luchini, Raul Araya-Secchi, Anne H. Bendsoe, Nanditha Shyam Prasad, Andreas Prestel, Marité Cardenas, Elena Pedraz-Cuesta, Lise Arleth, Stine F. Pedersen, Birthe B. Kragelund

Commun Biol. 2020; 3: 731. Published online 2020 Dec 3. doi: 10.1038/s42003-020-01455-6

PMCID:: PMC7713384

Abstract Article PDF–4.5M

Select item 766412015.

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane

Molly M. Hannigan, Alyson M. Hoffman, J. Will Thompson, Tianli Zheng, Christopher V. Nicchitta

Mol Cell Proteomics. 2020 Nov; 19(11): 1826–1849. Published online 2020 Aug 10. doi: 10.1074/mcp.RA120.002228

PMCID:: PMC7664120

Abstract Article PDF–4.8M

Select item 737664816.

Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia

Yan Jia, Wei Liu, Hui-En Zhan, Xiao-Ping Yi, Hui Liang, Qi-Li Zheng, Xin-Ya Jiang, Hai-Yan Zhou, Liang Zhao, Xie-Lan Zhao, Hui Zeng

J Hematol Oncol. 2020; 13: 101. Published online 2020 Jul 23. doi: 10.1186/s13045-020-00935-w

PMCID:: PMC7376648

Abstract Article PDF–3.0M

Select item 725962917.

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

Erika Liktor-Busa, Kiera T. Blawn, Kathryn L. Kellohen, Beth M. Wiese, Vani Verkhovsky, Jared Wahl, Anjali Vivek, Seph M. Palomino, Thomas P. Davis, Todd W. Vanderah, Tally M. Largent-Milnes

PLoS One. 2020; 15(5): e0227463. Published online 2020 May 29. doi: 10.1371/journal.pone.0227463

PMCID:: PMC7259629

Abstract Article PDF–2.5M

Select item 710434618.

Expression, Localization and Functional Activity of the Major Na⁺/H⁺ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe

Yan Yu, Anna Seidler, Kunyan Zhou, Zhenglin Yuan, Sunil Yeruva, Mahdi Amiri, Chris C. Yun, Katerina Nikolovska, Ursula Seidler

Cell Physiol Biochem. Author manuscript; available in PMC 2020 Mar 30.

Published in final edited form as: Cell Physiol Biochem. 2019; 52(5): 1017–1038. doi: 10.33594/000000070

PMCID:: PMC7104346

Abstract Article PDF–2.1M

Select item 692644519.

Overexpression of Na⁺/H⁺ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK

Shigeo Wakabayashi, Hirofumi Morihara, Shunichi Yokoe, Takatoshi Nakagawa, Kazumasa Moriwaki, Kiichiro Tomoda, Michio Asahi

J Biol Chem. 2019 Dec 20; 294(51): 19577–19588. Published online 2019 Nov 13. doi: 10.1074/jbc.RA119.010329

PMCID:: PMC6926445

Abstract Article PDF–3.5M

Select item 674682220.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

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