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Select item 112255771.

Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens

Stefen Andrianus, Maria A. Gubbiotti, Susan J. Mandel, Yuri E. Nikiforov, Zubair Baloch

Diagn Cytopathol. Author manuscript; available in PMC 2024 Jul 5.

Published in final edited form as: Diagn Cytopathol. 2023 Jul; 51(7): 406–413. Published online 2023 Apr 12. doi: 10.1002/dc.25138

PMCID:: PMC11225577

Abstract Article PDF–1.0M

Select item 111439232.

Mechanisms of thyrotropin receptor–mediated phenotype variability deciphered by gene mutations and M453T-knockin model

Kristiina Makkonen, Meeri Jännäri, Luís Crisóstomo, Matilda Kuusi, Konrad Patyra, Vladyslav Melnyk, Veli Linnossuo, Johanna Ojala, Rowmika Ravi, Christoffer Löf, Juho-Antti Mäkelä, Päivi Miettinen, Saila Laakso, Marja Ojaniemi, Jarmo Jääskeläinen, Markku Laakso, Filip Bossowski, Beata Sawicka, Karolina Stożek, Artur Bossowski, Gunnar Kleinau, Patrick Scheerer, FinnGen FinnGen, Mary Pat Reeve, Jukka Kero

JCI Insight. 2024 Feb 22; 9(4): e167092. Published online 2024 Jan 9. doi: 10.1172/jci.insight.167092

PMCID:: PMC11143923

Abstract Article PDF–20M

Select item 111317243.

Preferences of transmembrane helices for cooperative amplification of G_αs and G_αq signaling of the thyrotropin receptor

H. Jaeschke, G. Kleinau, J. Sontheimer, S. Mueller, G. Krause, R. Paschke

Cell Mol Life Sci. 2008 Dec; 65(24): 4028. Published online 2008 Nov 8. doi: 10.1007/s00018-008-8530-3

PMCID:: PMC11131724

Abstract Article PDF–828K

Select item 111055014.

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

Jana Fischer, Gunnar Kleinau, Claudia Rutz, Denise Zwanziger, Noushafarin Khajavi, Anne Müller, Maren Rehders, Klaudia Brix, Catherine L. Worth, Dagmar Führer, Heiko Krude, Burkhard Wiesner, Ralf Schülein, Heike Biebermann

Cell Mol Life Sci. 2018 Jun; 75(12): 2227–2239. Published online 2017 Dec 30. doi: 10.1007/s00018-017-2728-1

PMCID:: PMC11105501

Abstract Article PDF–2.9M

Select item 109830945.

A Novel TSHR Gene Mutation in a Family with Non-autoimmune Hyperthyroidism

Tamara Kufoof, Catherine Luxford, Kishani Kannangara, Roderick Clifton-Bligh, Kim C. Donaghue

Med Arch. 2024; 78(2): 154–158. doi: 10.5455/medarh.2024.78.154-158

PMCID:: PMC10983094

Abstract Article PDF–604K

Select item 109616196.

TSHR Variant Screening and Phenotype Analysis in 367 Chinese Patients With Congenital Hypothyroidism

Hai-Yang Zhang, Feng-Yao Wu, Xue-Song Li, Ping-Hui Tu, Cao-Xu Zhang, Rui-Meng Yang, Ren-Jie Cui, Chen-Yang Wu, Ya Fang, Liu Yang, Huai-Dong Song, Shuang-Xia Zhao

Ann Lab Med. 2024 Jul 1; 44(4): 343–353. Published online 2024 Mar 4. doi: 10.3343/alm.2023.0337

PMCID:: PMC10961619

Abstract Article PDF–1.4M

Select item 104145707.

Molecular investigation of TSHR gene in Bangladeshi congenital hypothyroid patients

Mst. Noorjahan Begum, Rumana Mahtarin, Md. Tarikul Islam, Sinthyia Ahmed, Tasnia Kawsar Konika, Kaiissar Mannoor, Sharif Akhteruzzaman, Firdausi Qadri

PLoS One. 2023; 18(8): e0282553. Published online 2023 Aug 10. doi: 10.1371/journal.pone.0282553

PMCID:: PMC10414570

Abstract Article PDF–2.6M

Select item 102818468.

Eighteen-years follow-up of congenital hypothyroidism by TSHR gene p.Arg109Gln and p.Arg450His variants

Daisuke Watanabe, Hideaki Yagasaki, Yumiko Mitsui, Takeshi Inukai

Nagoya J Med Sci. 2023 May; 85(2): 369–374. doi: 10.18999/nagjms.85.2.369

PMCID:: PMC10281846

Abstract Article PDF–3.0M

Select item 99788749.

Патогенные варианты гена <i>TSHR</i> у детей с дисгенезией щитовидной железы

Е. В. Шрёдер, Т. А. Вадина, Е. Н. Солодовникова, В. В. Захарова, М. В. Дегтярев, М. Б. Конюхова, Н. В. Сергеева, О. Б. Безлепкина

Probl Endokrinol (Mosk) 2023; 69(1): 76–85. Russian. Published online 2023 Feb 25. doi: 10.14341/probl13210

PMCID:: PMC9978874

Abstract Article PDF–670K

Select item 981555310.

Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations

Dorota Whitmer, John E. Phay, Shelby Holt, Benjamin O’Donnell, Jay Nguyen, Dennis Joseph, Anthony Chi, Shuyang Wu, Yangyang Hao, Jing Huang, Joshua P. Klopper, Richard T. Kloos, Giulia C. Kennedy, Joyce Shin

Front Endocrinol (Lausanne) 2022; 13: 1073592. Published online 2022 Dec 22. doi: 10.3389/fendo.2022.1073592

PMCID:: PMC9815553

Abstract Article PDF–996K

Select item 967802411.

Autoantibody mimicry of hormone action at the thyrotropin receptor

Bryan Faust, Christian B. Billesbølle, Carl-Mikael Suomivuori, Isha Singh, Kaihua Zhang, Nicholas Hoppe, Antonio F. M. Pinto, Jolene K. Diedrich, Yagmur Muftuoglu, Mariusz W. Szkudlinski, Alan Saghatelian, Ron O. Dror, Yifan Cheng, Aashish Manglik

Nature. Author manuscript; available in PMC 2022 Nov 21.

Published in final edited form as: Nature. 2022 Sep; 609(7928): 846–853. Published online 2022 Aug 8. doi: 10.1038/s41586-022-05159-1

PMCID:: PMC9678024

Abstract Article PDF–8.1M

Select item 949278212.

Association of TSHR gene single nucleotide intronic polymorphism with the risk of hypothyroid and hyperthyroid disorders in Yazd province

Fahime Sadat Naghibi, Seyed Mohsen Miresmaeili, Amaneh Javid

Sci Rep. 2022; 12: 15745. Published online 2022 Sep 21. doi: 10.1038/s41598-022-19822-0

PMCID:: PMC9492782

Abstract Article PDF–1.2M

Select item 933519313.

Brief Report - Monoclonal Antibodies Illustrate the Difficulties in Measuring Blocking TSH Receptor Antibodies

Terry F. Davies, Syed A. Morshed, Mihaly Mezei, Rauf Latif

Front Endocrinol (Lausanne) 2022; 13: 943459. Published online 2022 Jul 15. doi: 10.3389/fendo.2022.943459

PMCID:: PMC9335193

Abstract Article PDF–1.3M

Select item 931506214.

The Mysterious Universe of the TSH Receptor

Inês Henriques Vieira, Dírcea Rodrigues, Isabel Paiva

Front Endocrinol (Lausanne) 2022; 13: 944715. Published online 2022 Jul 12. doi: 10.3389/fendo.2022.944715

PMCID:: PMC9315062

Abstract Article PDF–434K

Select item 872561715.

TSH Stimulation of Human Thyroglobulin and Thyroid Peroxidase Gene Transcription Is Partially Dependent on Internalization

Daesong Jang, Elena Eliseeva, Joanna Klubo-Gwiezdzinska, Susanne Neumann, Marvin C. Gershengorn

Cell Signal. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Cell Signal. 2022 Feb; 90: 110212. Published online 2021 Dec 9. doi: 10.1016/j.cellsig.2021.110212

PMCID:: PMC8725617

Abstract Article PDF–903K

Select item 818349416.

Implications of an Improved Model of the TSH Receptor Transmembrane Domain (TSHR-TMD-TRIO)

Mihaly Mezei, Rauf Latif, Bhaskar Das, Terry F Davies

Endocrinology. 2021 Jul; 162(7): bqab051. Published online 2021 Mar 8. doi: 10.1210/endocr/bqab051

PMCID:: PMC8183494

Abstract Article

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 744700318.

The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

Mihaly Mezei, Ramkumarie Baliram, M Rejwan Ali, Mone Zaidi, Terry F Davies, Rauf Latif

Endocrinology. 2020 Sep; 161(9): bqaa125. Published online 2020 Aug 1. doi: 10.1210/endocr/bqaa125

PMCID:: PMC7447003

Abstract Article

Select item 688835719.

The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR

Laura Kalveram, Gunnar Kleinau, Kamila Szymańska, Patrick Scheerer, Adolfo Rivero-Müller, Annette Grüters-Kieslich, Heike Biebermann

Int J Mol Sci. 2019 Nov; 20(22): 5564. Published online 2019 Nov 7. doi: 10.3390/ijms20225564

PMCID:: PMC6888357

Abstract Article PDF–7.3M

Select item 677813720.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

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PMC Links for GEO Profiles (Select 65818723) (111)
PMC
Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA
Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA
gi|260263757|ref|NM_212509.2|

Nucleotide
Mus musculus cDNA clone IMAGE:40111511, containing frame-shift errors
Mus musculus cDNA clone IMAGE:40111511, containing frame-shift errors
gi|126361993|gb|BC131686.1|

Nucleotide
ndhE [Cardamine lyrata]
ndhE [Cardamine lyrata]
Gene ID:71471861

Gene

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