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Items: 1 to 20 of 38

1.
Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity
Julia Castillo-González, José Luis Ruiz, Ignacio Serrano-Martínez, Irene Forte-Lago, Ana Ubago-Rodriguez, Marta Caro, Jesús Miguel Pérez-Gómez, Alejandro Benítez-Troncoso, Eduardo Andrés-León, Macarena Sánchez-Navarro, Raúl M. Luque, Elena González-Rey
J Neuroinflammation. 2023; 20: 226. Published online 2023 Oct 4. doi: 10.1186/s12974-023-02908-5
PMCID:
PMC10548650
AbstractArticlePDF–16M
2.
Somatostatin, Cortistatin and Their Receptors Exert Antitumor Actions in Androgen-Independent Prostate Cancer Cells: Critical Role of Endogenous Cortistatin
Prudencio Sáez-Martínez, Francisco Porcel-Pastrana, Jesús M. Pérez-Gómez, Sergio Pedraza-Arévalo, Enrique Gómez-Gómez, Juan M. Jiménez-Vacas, Manuel D. Gahete, Raúl M. Luque
Int J Mol Sci. 2022 Nov; 23(21): 13003. Published online 2022 Oct 27. doi: 10.3390/ijms232113003
PMCID:
PMC9654089
AbstractArticlePDF–2.2M
3.
Structural insights into human CCAN complex assembled onto DNA
Tian Tian, Lili Chen, Zhen Dou, Zhisen Yang, Xinjiao Gao, Xiao Yuan, Chengliang Wang, Ran Liu, Zuojun Shen, Ping Gui, Maikun Teng, Xianlei Meng, Donald L. Hill, Lin Li, Xuan Zhang, Xing Liu, Linfeng Sun, Jianye Zang, Xuebiao Yao
Cell Discov. 2022; 8: 90. Published online 2022 Sep 9. doi: 10.1038/s41421-022-00439-6
PMCID:
PMC9463443
AbstractArticlePDF–5.7M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation
Yunpeng Zhao, Cheng Qiu, Wenhan Wang, Jiangfan Peng, Xiang Cheng, Yangtao Shangguan, Mingyang Xu, Jiayi Li, Ruize Qu, Xiaomin Chen, Suyi Jia, Dan Luo, Long Liu, Peng Li, Fengjin Guo, Krasimir Vasilev, Liang Liu, John Hayball, Shuli Dong, Xin Pan, Yuhua Li, Linlin Guo, Lei Cheng, Weiwei Li
Theranostics. 2020; 10(15): 7015–7033. Published online 2020 May 27. doi: 10.7150/thno.45359
PMCID:
PMC7295059
AbstractArticlePDF–4.1M
6.
Comparison of predictive value of NT-proBNP, sST2 and MMPs in heart failure patients with different ejection fractions
Wei Pan, Donghui Yang, Peng Yu, Huizhen Yu
BMC Cardiovasc Disord. 2020; 20: 208. Published online 2020 Apr 30. doi: 10.1186/s12872-020-01493-2
PMCID:
PMC7193418
AbstractArticlePDF–1.0M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras
Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510
Correction in:
Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.
PMCID:
PMC6735892
AbstractArticlePDF–5.4M
9.
Cortistatin binds to TNF-α receptors and protects against osteoarthritis
Yunpeng Zhao, Yuhua Li, Ruize Qu, Xiaomin Chen, Wenhan Wang, Cheng Qiu, Ben Liu, Xin Pan, Liang Liu, Krasimir Vasilev, John Hayball, Shuli Dong, Weiwei Li
EBioMedicine. 2019 Mar; 41: 556–570. Published online 2019 Feb 28. doi: 10.1016/j.ebiom.2019.02.035
PMCID:
PMC6443028
AbstractArticlePDF–5.5M
10.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response
Arun Pradhan, Vladimir Ustiyan, Yufang Zhang, Tanya V. Kalin, Vladimir V. Kalinichenko
Oncotarget. 2016 Jan 12; 7(2): 1912–1926. Published online 2015 Nov 28. doi: 10.18632/oncotarget.6422
PMCID:
PMC4811506
AbstractArticlePDF–4.9M
13.
The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety
Sang Jun Han, Khurshida Begum, Charles E. Foulds, Ross A. Hamilton, Suzanna Bailey, Anna Malovannaya, Doug Chan, Jun Qin, Bert W. O’Malley
Mol Pharmacol. 2016 Jan; 89(1): 14–26. Published online 2016 Jan. doi: 10.1124/mol.115.100925
PMCID:
PMC4702103
AbstractArticlePDF–1.6M
14.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
15.
The CENP-T C-Terminus Is Exclusively Proximal to H3.1 and not to H3.2 or H3.3
Christian Abendroth, Antje Hofmeister, Sandra B. Hake, Paul K. Kamweru, Elke Miess, Carsten Dornblut, Isabell Küffner, Wen Deng, Heinrich Leonhardt, Sandra Orthaus, Christian Hoischen, Stephan Diekmann
Int J Mol Sci. 2015 Mar; 16(3): 5839–5863. Published online 2015 Mar 12. doi: 10.3390/ijms16035839
PMCID:
PMC4394509
AbstractArticlePDF–2.2M
16.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
17.
FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers
Chloe Girard, Wayne Crismani, Nicole Froger, Julien Mazel, Afef Lemhemdi, Christine Horlow, Raphael Mercier
Nucleic Acids Res. 2014 Aug 18; 42(14): 9087–9095. Published online 2014 Jul 18. doi: 10.1093/nar/gku614
PMCID:
PMC4132730
AbstractArticlePDF–3.1M
18.
The RSF1 Histone-Remodelling Factor Facilitates DNA Double-Strand Break Repair by Recruiting Centromeric and Fanconi Anaemia Proteins
Fabio Pessina, Noel F. Lowndes
PLoS Biol. 2014 May; 12(5): e1001856. Published online 2014 May 6. doi: 10.1371/journal.pbio.1001856
Correction in:
PLoS Biol. 2017 Feb; 15(2): e1002595.
Expression of Concern in:
PLoS Biol. 2024 May; 22(5): e3002635.
PMCID:
PMC4011676
AbstractArticlePDF–3.0M
19.
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability
David Fox, 3rd, Zhijiang Yan, Chen Ling, Ye Zhao, Duck-Yeon Lee, Tatsuo Fukagawa, Wei Yang, Weidong Wang
Cell Res. 2014 May; 24(5): 560–575. Published online 2014 Apr 4. doi: 10.1038/cr.2014.42
PMCID:
PMC4011343
AbstractArticlePDF–1.2M
20.
MHF complex senses branched DNA via binding a pair of crossover DNA duplexes
Qi Zhao, Dorina Saro, Aristidis Sachpatzidis, Thiyam Ramsing Singh, Daniel Schlingman, Xiao-Feng Zheng, Andrew Mack, Miaw-Sheue Tsai, Simon Mochrie, Lynne Regan, Amom Ruhikanta Meetei, Patrick Sung, Yong Xiong
Nat Commun. Author manuscript; available in PMC 2014 Jul 1.
Published in final edited form as: Nat Commun. 2014; 5: 2987. doi: 10.1038/ncomms3987
PMCID:
PMC3967914
AbstractArticlePDF–4.5M

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