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Select item 102670171.

CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma

Luiz Henrique Geraldo, Celina Garcia, Yunling Xu, Felipe Saceanu Leser, Izabella Grimaldi, Eduardo Sabino de Camargo Magalhães, Joost Dejaegher, Lien Solie, Cláudia Maria Pereira, Ana Helena Correia, Steven De Vleeschouwer, Bertrand Tavitian, Nathalie Henriques Silva Canedo, Thomas Mathivet, Jean-Leon Thomas, Anne Eichmann, Flavia Regina Souza Lima

Cell Mol Life Sci. 2023 Jul; 80(7): 179. Published online 2023 Jun 14. doi: 10.1007/s00018-023-04788-7

PMCID:: PMC10267017

Abstract Article PDF–10M

Select item 101995592.

CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer

Danhua Xu, Xu Liu, Shouyu Ke, Yixian Guo, Chunchao Zhu, Hui Cao

BMC Cancer. 2023; 23: 464. Published online 2023 May 19. doi: 10.1186/s12885-023-10882-7

PMCID:: PMC10199559

Abstract Article PDF–1.4M

Select item 100870243.

CCR7 alterations associated with inferior outcome of adult T‐cell leukemia/lymphoma under mogamulizumab treatment

Yuma Sakamoto, Takashi Ishida, Ayako Masaki, Takayuki Murase, Eiichi Ohtsuka, Morishige Takeshita, Reiji Muto, Hiromi Iwasaki, Asahi Ito, Shigeru Kusumoto, Nobuaki Nakano, Masahito Tokunaga, Kentaro Yonekura, Yukie Tashiro, Shinsuke Iida, Atae Utsunomiya, Ryuzo Ueda, Hiroshi Inagaki

Hematol Oncol. 2022 Dec; 40(5): 876–884. Published online 2022 Sep 6. doi: 10.1002/hon.3072

PMCID:: PMC10087024

Abstract Article PDF–772K

Select item 100402474.

CCL21/CCR7 signaling in macrophages promotes joint inflammation and Th17-mediated osteoclast formation in rheumatoid arthritis

Katrien Van Raemdonck, Sadiq Umar, Karol Palasiewicz, Suncica Volkov, Michael V. Volin, Shiva Arami, Huan J. Chang, Brian Zanotti, Nadera Sweiss, Shiva Shahrara

Cell Mol Life Sci. 2020 Apr; 77(7): 1387–1399. Published online 2019 Jul 24. doi: 10.1007/s00018-019-03235-w

PMCID:: PMC10040247

Abstract Article PDF–8.4M

Select item 98669485.

Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling

Marc Artinger, Oliver J. Gerken, Daniel F. Legler

Int J Mol Sci. 2023 Jan; 24(2): 1670. Published online 2023 Jan 14. doi: 10.3390/ijms24021670

PMCID:: PMC9866948

Abstract Article PDF–2.7M

Select item 95714296.

Effects of let-7a microRNA and C–C chemokine receptor type 7 expression on cellular function and prognosis in esophageal squamous cell carcinoma

Masahiro Yura, Kazumasa Fukuda, Satoru Matsuda, Tomoyuki Irino, Rieko Nakamura, Hirofumi Kawakubo, Hiroya Takeuchi, Yuko Kitagawa

BMC Cancer. 2022; 22: 1064. Published online 2022 Oct 15. doi: 10.1186/s12885-022-10178-2

PMCID:: PMC9571429

Abstract Article PDF–1.4M

Select item 90053257.

lncRNA DARS-AS1 Promoted Osteosarcoma Progression through Regulating miR-532-3p/CCR7

Yan Xue, Hongmiao Liu, Guangchen Nie, Xiaoping Ren

Dis Markers. 2022; 2022: 4660217. Published online 2022 Apr 5. doi: 10.1155/2022/4660217

PMCID:: PMC9005325

Abstract Article PDF–1.8M

Select item 89908608.

CXCL12 promotes CCR7 ligand–mediated breast cancer cell invasion and migration toward lymphatic vessels

Haruko Hayasaka, Junichi Yoshida, Yasutaka Kuroda, Akihiro Nishiguchi, Michiya Matsusaki, Kei Kishimoto, Hitoshi Nishimura, Mari Okada, Yuki Shimomura, Daichi Kobayashi, Yoshihito Shimazu, Yuji Taya, Mitsuru Akashi, Masayuki Miyasaka

Cancer Sci. 2022 Apr; 113(4): 1338–1351. Published online 2022 Feb 14. doi: 10.1111/cas.15293

PMCID:: PMC8990860

Abstract Article PDF–1.6M

Select item 88703719.

C-C Chemokine Receptor 7 in Cancer

Colin A. Bill, Christopher M. Allen, Charlotte M. Vines

Cells. 2022 Feb; 11(4): 656. Published online 2022 Feb 14. doi: 10.3390/cells11040656

PMCID:: PMC8870371

Abstract Article PDF–2.2M

Select item 855817910.

The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

Astrid Sissel Jørgensen, Emma Probst Brandum, Jeppe Malthe Mikkelsen, Klaudia A. Orfin, Ditte Rahbæk Boilesen, Kristoffer Lihme Egerod, Natasha A. Moussouras, Frederik Vilhardt, Pawel Kalinski, Per Basse, Yen-Hsi Chen, Zhang Yang, Michael B. Dwinell, Brian F. Volkman, Christopher T. Veldkamp, Peter Johannes Holst, Katharina Lahl, Christoffer Knak Goth, Mette Marie Rosenkilde, Gertrud Malene Hjortø

Cell Mol Life Sci. 2021 Nov; 78(21-22): 6963–6978. Published online 2021 Sep 29. doi: 10.1007/s00018-021-03930-7

PMCID:: PMC8558179

Abstract Article PDF–3.4M

Select item 787796111.

Arrestin 3 Mediates Endocytosis of CCR7 Following Ligation of CCL19 but not CCL21

Melissa A. Byers, Psachal A. Calloway, Laurie Shannon, Heather D. Cunningham, Sarah Smith, Fang Li, Brian C. Fassold, Charlotte M. Vines

J Immunol. Author manuscript; available in PMC 2021 Feb 11.

Published in final edited form as: J Immunol. 2008 Oct 1; 181(7): 4723–4732. doi: 10.4049/jimmunol.181.7.4723

PMCID:: PMC7877961

Abstract Article PDF–1.3M

Select item 769427412.

Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7–CCL21 Axis Modulated by TNF-α

Shuai Zhang, Hongzheng Wang, Zhiyun Xu, Yongkang Bai, Lin Xu

Genes (Basel) 2020 Nov; 11(11): 1309. Published online 2020 Nov 4. doi: 10.3390/genes11111309

PMCID:: PMC7694274

Abstract Article PDF–3.6M

Select item 752957413.

Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non‐small cell lung cancer

Zhao Yue, Ding Ningning, Yang Lin, Ying Jianming, Zhang Hongtu, Yuan Ligong, Li Feng, Wang Shuaibo, Mao Yousheng

Thorac Cancer. 2020 Oct; 11(10): 2955–2965. Published online 2020 Sep 8. doi: 10.1111/1759-7714.13645

PMCID:: PMC7529574

Abstract Article PDF–5.5M

Select item 722428814.

Deletion of self-reactive CCR7– thymocytes in the absence of MHC expression on thymic epithelial cells

Rushika C. Wirasinha, Anna Chan, Jin Yan Yap, Daniel Y. Hu, Charis E. Teh, Daniel H. D. Gray, Christopher C. Goodnow, Stephen R. Daley

Cell Death Differ. 2019 Dec; 26(12): 2727–2739. Published online 2019 Apr 24. doi: 10.1038/s41418-019-0331-8

PMCID:: PMC7224288

Abstract Article PDF–2.8M

Select item 713961115.

Integrated miRNA/mRNA Counter-Expression Analysis Highlights Oxidative Stress-Related Genes CCR7 and FOXO1 as Blood Markers of Coronary Arterial Disease

Miguel Hueso, Adrián Mallén, Ángela Casas, Jordi Guiteras, Fabrizio Sbraga, Arnau Blasco-Lucas, Núria Lloberas, Joan Torras, Josep M Cruzado, Estanislao Navarro

Int J Mol Sci. 2020 Mar; 21(6): 1943. Published online 2020 Mar 12. doi: 10.3390/ijms21061943

PMCID:: PMC7139611

Abstract Article PDF–1.5M

Select item 680477816.

The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy

Georgios L. Moschovakis, Anja Bubke, Michaela Friedrichsen, Jasmin Ristenpart, Jaap Willem Back, Christine S. Falk, Elisabeth Kremmer, Reinhold Förster

Cell Mol Immunol. 2019 Oct; 16(10): 791–799. Published online 2018 Jul 4. doi: 10.1038/s41423-018-0056-5

PMCID:: PMC6804778

Abstract Article PDF–4.3M

Select item 677813717.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 677442018.

Ets-1 enhances tumor migration through regulation of CCR7 expression

Li-Wen Fang, Ying-Hsien Kao, Ya-Ting Chuang, Huey-Lan Huang, Tzong-Shyuan Tai

BMB Rep. 2019 Sep; 52(9): 548–553. Published online 2019 Sep 30. doi: 10.5483/BMBRep.2019.52.9.232

PMCID:: PMC6774420

Abstract Article PDF–1.8M

Select item 675317819.

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

Astrid S. Jørgensen, Olav Larsen, Edith Uetz-von Allmen, Michael Lückmann, Daniel F. Legler, Thomas M. Frimurer, Christopher T. Veldkamp, Gertrud M. Hjortø, Mette M. Rosenkilde

Front Immunol. 2019; 10: 2156. Published online 2019 Sep 13. doi: 10.3389/fimmu.2019.02156

PMCID:: PMC6753178

Abstract Article PDF–1.7M

Select item 648550720.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269

PMCID:: PMC6485507

Abstract Article PDF–4.4M

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PMC Links for GEO Profiles (Select 65020091) (116)
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OMIM Links for Protein (Select 400153471) (6)
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NADH dehydrogenase subunit 4L (mitochondrion) [Callithrix geoffroyi]
NADH dehydrogenase subunit 4L (mitochondrion) [Callithrix geoffroyi]
gi|529217175|ref|YP_008378899.1|

Protein
Rattus norvegicus G protein pathway suppressor 1 (Gps1), transcript variant 1, m...
Rattus norvegicus G protein pathway suppressor 1 (Gps1), transcript variant 1, mRNA
gi|400153470|ref|NM_053969.3|

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