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Select item 109168661.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 92792852.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81498514.

INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer

Samuel J. Rodgers, Lisa M. Ooms, Viola M. J. Oorschot, Ralf B. Schittenhelm, Elizabeth V. Nguyen, Sabryn A. Hamila, Natalie Rynkiewicz, Rajendra Gurung, Matthew J. Eramo, Absorn Sriratana, Clare G. Fedele, Franco Caramia, Sherene Loi, Genevieve Kerr, Helen E. Abud, Georg Ramm, Antonella Papa, Andrew M. Ellisdon, Roger J. Daly, Catriona A. McLean, Christina A. Mitchell

Nat Commun. 2021; 12: 3140. Published online 2021 May 25. doi: 10.1038/s41467-021-23241-6

PMCID:: PMC8149851

Abstract Article PDF–4.2M

Select item 80566795.

Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells

Youliang Wu, Delong Meng, Xin Xu, Junjun Bao, Yexiang You, Yanjun Sun, Yongxiang Li, Dengqun Sun

BMC Cancer. 2021; 21: 433. Published online 2021 Apr 20. doi: 10.1186/s12885-021-08143-6

PMCID:: PMC8056679

Abstract Article PDF–7.8M

Select item 78446736.

miR-1290 Contributes to Colorectal Cancer Cell Proliferation by Targeting INPP4B

Qingzhu Ma, Yan Wang, Hualing Zhang, Fengqiang Wang

Oncol Res. 2018; 26(8): 1167–1174. Published online 2018 Sep 14. doi: 10.3727/096504017X15051741798389

PMCID:: PMC7844673

Abstract Article PDF–7.7M

Select item 75848877.

Estrogen receptor β regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3

Surendra Chaurasiya, Wanfu Wu, Anders M. Strom, Margaret Warner, Jan-Åke Gustafsson

Proc Natl Acad Sci U S A. 2020 Oct 20; 117(42): 26347–26355. Published online 2020 Oct 5. doi: 10.1073/pnas.2007160117

PMCID:: PMC7584887

Abstract Article PDF–2.5M

Select item 71837908.

TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K–C2α-, and INPP4B-mediated phosphoinositide conversions

Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa

Mol Biol Cell. 2020 Mar 1; 31(5): 360–372. doi: 10.1091/mbc.E19-11-0662

PMCID:: PMC7183790

Abstract Article PDF–3.6M

Select item 69543699.

Genetic interactions between INPP4B and RAD50 is prognostic of breast cancer survival

Xiao Chen, Rutaganda Theobard, Jianying Zhang, Xiaofeng Dai

Biosci Rep. 2020 Jan 31; 40(1): BSR20192546. Published online 2020 Jan 10. doi: 10.1042/BSR20192546

PMCID:: PMC6954369

Abstract Article PDF–1.5M

Select item 637730310.

Inositol Polyphosphate 4-phosphatase Type II Regulation of Androgen Receptor Activity

Manqi Zhang, Egla Suarez, Judy L. Vasquez, Lubov Nathanson, Leif E. Peterson, Kimal Rajapakshe, Paul Basil, Nancy L. Weigel, Cristian Coarfa, Irina U. Agoulnik

Oncogene. Author manuscript; available in PMC 2019 Mar 18.

Published in final edited form as: Oncogene. 2019 Feb; 38(7): 1121–1135. Published online 2018 Sep 18. doi: 10.1038/s41388-018-0498-3

PMCID:: PMC6377303

Abstract Article PDF–2.5M

Select item 590810711.

INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway

Ying Chen, Zeyu Sun, Mei Qi, Xiao Wang, Weifang Zhang, Chunyan Chen, Juan Liu, Weiming Zhao

J Cell Mol Med. 2018 May; 22(5): 2935–2943. Published online 2018 Mar 7. doi: 10.1111/jcmm.13595

PMCID:: PMC5908107

Abstract Article PDF–1.4M

Select item 580289012.

SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML

Irakli Dzneladze, John F. Woolley, Carla Rossell, Youqi Han, Ayesha Rashid, Michael Jain, Jüri Reimand, Mark D. Minden, Leonardo Salmena

PLoS One. 2018; 13(2): e0191510. Published online 2018 Feb 7. doi: 10.1371/journal.pone.0191510

Correction in:: PLoS One. 2018; 13(3): e0195417.

PMCID:: PMC5802890

Abstract Article PDF–9.5M

Select item 577304413.

INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia

Hongjun Jin, Liyuan Yang, Lu Wang, Zailin Yang, Qian Zhan, Yao Tao, Qin Zou, Yuting Tang, Jingrong Xian, Shuaishuai Zhang, Yipei Jing, Ling Zhang

J Exp Clin Cancer Res. 2018; 37: 8. Published online 2018 Jan 17. doi: 10.1186/s13046-018-0675-9

PMCID:: PMC5773044

Abstract Article PDF–2.8M

Select item 550282614.

INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC

Darien E. Reed, Kevan M. Shokat

Mol Cancer Res. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Mol Cancer Res. 2017 Jun; 15(6): 765–775. Published online 2017 Feb 14. doi: 10.1158/1541-7786.MCR-16-0183

PMCID:: PMC5502826

Abstract Article PDF–1.5M

Select item 490843815.

INPP4B is an oncogenic regulator in human colon cancer

S T Guo, M N Chi, R H Yang, X Y Guo, L K Zan, C Y Wang, Y F Xi, L Jin, A Croft, H-Y Tseng, X G Yan, M Farrelly, F H Wang, F Lai, J F Wang, Y P Li, S Ackland, R Scott, I U Agoulnik, H Hondermarck, R F Thorne, T Liu, X D Zhang, C C Jiang

Oncogene. 2016 Jun 9; 35(23): 3049–3061. Published online 2015 Sep 28. doi: 10.1038/onc.2015.361

PMCID:: PMC4908438

Abstract Article PDF–4.2M

Select item 481716416.

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131

Radhika A. Varier, Enrique Carrillo de Santa Pau, Petra van der Groep, Rik G. H. Lindeboom, Filomena Matarese, Anneloes Mensinga, Arne H. Smits, Raghu Ram Edupuganti, Marijke P. Baltissen, Pascal W. T. C. Jansen, Natalie ter Hoeve, Danny R. van Weely, Ina Poser, Paul J. van Diest, Hendrik G. Stunnenberg, Michiel Vermeulen

J Biol Chem. 2016 Apr 1; 291(14): 7313–7324. Published online 2016 Feb 3. doi: 10.1074/jbc.M115.701227

PMCID:: PMC4817164

Abstract Article PDF–3.5M

Select item 480797817.

Endosome and INPP4B

Chen Li Chew, Ming Chen, Pier Paolo Pandolfi

Oncotarget. 2016 Jan 5; 7(1): 5–6. Published online 2015 Dec 18. doi: 10.18632/oncotarget.6663

PMCID:: PMC4807978

Article PDF–673K

Select item 474186818.

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

Meng Na Chi, Su Tang Guo, James S. Wilmott, Xiang Yun Guo, Xu Guang Yan, Chun Yan Wang, Xiao Ying Liu, Lei Jin, Hsin-Yi Tseng, Tao Liu, Amanda Croft, Hubert Hondermarck, Richard A. Scolyer, Chen Chen Jiang, Xu Dong Zhang

Oncotarget. 2015 Nov 24; 6(37): 39891–39907. Published online 2015 Nov 9. doi: 10.18632/oncotarget.5359

PMCID:: PMC4741868

Abstract Article PDF–4.4M

Select item 457872319.

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities

Sandra M. Lopez, Myles C. Hodgson, Charles Packianathan, Ozlem Bingol-Ozakpinar, Fikriye Uras, Barry P. Rosen, Irina U. Agoulnik

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Sep 22.

Published in final edited form as: Biochem Biophys Res Commun. 2013 Oct 18; 440(2): 277–282. Published online 2013 Sep 23. doi: 10.1016/j.bbrc.2013.09.077

PMCID:: PMC4578723

Abstract Article PDF–598K

Select item 449784320.

In vivo role of INPP4B in tumor and metastasis suppression through regulation of PI3K/AKT signaling at endosomes

Chen Li Chew, Andrea Lunardi, Federico Gulluni, Daniel T. Ruan, Ming Chen, Leonardo Salmena, Michiya Nishino, Antonella Papa, Christopher Ng, Jacqueline Fung, John G. Clohessy, Junko Sasaki, Takehiko Sasaki, Roderick T. Bronson, Emilio Hirsch, Pier Paolo Pandolfi

Cancer Discov. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Cancer Discov. 2015 Jul; 5(7): 740–751. Published online 2015 Apr 16. doi: 10.1158/2159-8290.CD-14-1347

PMCID:: PMC4497843

Abstract Article PDF–1.0M

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