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Items: 1 to 20 of 138

1.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang
eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168
PMCID:
PMC10901513
AbstractArticlePDF–9.2M
2.
Polycomb repressive complex 2 regulates basal cell fate during adult olfactory neurogenesis
Tiffany Ko, Rhea Choi, Khalil Issa, Rupali Gupta, Edward Llinas, Lluis Morey, John B. Finlay, Bradley J. Goldstein
Stem Cell Reports. 2023 Nov 14; 18(11): 2283–2296. Published online 2023 Oct 12. doi: 10.1016/j.stemcr.2023.09.008
PMCID:
PMC10679661
AbstractArticlePDF–3.6M
3.
SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development
Yurika Matsui, Mohamed Nadhir Djekidel, Katherine Lindsay, Parimal Samir, Nina Connolly, Gang Wu, Xiaoyang Yang, Yiping Fan, Beisi Xu, Jamy C. Peng
Nat Commun. 2023; 14: 4754. Published online 2023 Aug 8. doi: 10.1038/s41467-023-40487-4
PMCID:
PMC10409800
AbstractArticlePDF–5.3M
4.
Epigenetic dosage identifies two major and functionally distinct β-cell subtypes
Erez Dror, Luca Fagnocchi, Vanessa Wegert, Stefanos Apostle, Brooke Grimaldi, Tim Gruber, Ilaria Panzeri, Steffen Heyne, Kira Daniela Höffler, Victor Kreiner, Reagan Ching, Tess Tsai-Hsiu Lu, Ayush Semwal, Ben Johnson, Parijat Senapati, Adelheid Lempradl, Dustin Schones, Axel Imhof, Hui Shen, John Andrew Pospisilik
Cell Metab. Author manuscript; available in PMC 2024 May 2.
Published in final edited form as: Cell Metab. 2023 May 2; 35(5): 821–836.e7. Published online 2023 Mar 21. doi: 10.1016/j.cmet.2023.03.008
PMCID:
PMC10160009
AbstractArticlePDF–3.2M
5.
PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth
Abigail H. Cleveland, Daniel Malawsky, Mehal Churiwal, Claudia Rodriguez, Frances Reed, Matthew Schniederjan, Jose E. Velazquez Vega, Ian Davis, Timothy R. Gershon
Acta Neuropathol Commun. 2023; 11: 8. Published online 2023 Jan 12. doi: 10.1186/s40478-023-01508-x
PMCID:
PMC9838053
AbstractArticlePDF–17M
6.
The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis
Shuang-Feng Zhang, Shang-Kun Dai, Hong-Zhen Du, Hui Wang, Xing-Guo Li, Yi Tang, Chang-Mei Liu
Stem Cell Reports. 2022 Sep 13; 17(9): 2064–2080. Published online 2022 Aug 4. doi: 10.1016/j.stemcr.2022.07.004
PMCID:
PMC9481917
AbstractArticlePDF–9.5M
7.
PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons
Konstantinos Toskas, Behzad Yaghmaeian-Salmani, Olga Skiteva, Wojciech Paslawski, Linda Gillberg, Vasiliki Skara, Irene Antoniou, Erik Södersten, Per Svenningsson, Karima Chergui, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Sci Adv. 2022 Aug; 8(34): eabo1543. Published online 2022 Aug 26. doi: 10.1126/sciadv.abo1543
PMCID:
PMC9417181
AbstractArticlePDF–6.2M
8.
PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma
Jiaqing Yi, BongWoo Kim, Xuanming Shi, Xiaoming Zhan, Q. Richard Lu, Zhenyu Xuan, Jiang Wu
Cancer Res. Author manuscript; available in PMC 2023 Feb 16.
Published in final edited form as: Cancer Res. 2022 Aug 16; 82(16): 2874–2886. doi: 10.1158/0008-5472.CAN-21-4313
PMCID:
PMC9388591
AbstractArticlePDF–3.7M
9.
EED is required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad
Matthew G. Lowe, Ming-Ren Yen, Fei-man Hsu, Linzi Hosohama, Zhongxun Hu, Tsotne Chitiashvili, Timothy Hunt, Isaac Gorgy, Matthew Bernard, Sissy Wamaitha, Pao-Yang Chen, Amander T. Clark
Dev Cell. Author manuscript; available in PMC 2023 Jun 20.
Published in final edited form as: Dev Cell. 2022 Jun 20; 57(12): 1482–1495.e5. Published online 2022 Jun 8. doi: 10.1016/j.devcel.2022.05.012
PMCID:
PMC9278986
AbstractArticlePDF–1.6M
10.
Noncanonical imprinting sustains embryonic development and restrains placental overgrowth
Shogo Matoba, Chisayo Kozuka, Kento Miura, Kimiko Inoue, Mami Kumon, Ryoya Hayashi, Tatsuya Ohhata, Atsuo Ogura, Azusa Inoue
Genes Dev. 2022 Apr 1; 36(7-8): 483–494. doi: 10.1101/gad.349390.122
PMCID:
PMC9067403
AbstractArticlePDF–9.6M
11.
Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes
Behzad Yaghmaeian Salmani, Brad Balderson, Susanne Bauer, Helen Ekman, Annika Starkenberg, Thomas Perlmann, Michael Piper, Mikael Bodén, Stefan Thor
Development. 2022 Mar 1; 149(5): dev200076. Published online 2022 Mar 7. doi: 10.1242/dev.200076
PMCID:
PMC8959139
AbstractArticle
12.
Variational autoencoding of gene landscapes during mouse CNS development uncovers layered roles of Polycomb Repressor Complex 2
Ariane Mora, Jonathan Rakar, Ignacio Monedero Cobeta, Behzad Yaghmaeian Salmani, Annika Starkenberg, Stefan Thor, Mikael Bodén
Nucleic Acids Res. 2022 Feb 22; 50(3): 1280–1296. Published online 2022 Jan 20. doi: 10.1093/nar/gkac006
PMCID:
PMC8860581
AbstractArticlePDF–8.1M
13.
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
Wei Gu, Hua Wang, Xiaofeng Huang, Judith Kraiczy, Pratik N. P. Singh, Charles Ng, Sezin Dagdeviren, Sean Houghton, Oscar Pellon-Cardenas, Ying Lan, Yaohui Nie, Jiaoyue Zhang, Kushal K Banerjee, Emily J. Onufer, Brad W. Warner, Jason Spence, Ellen Scherl, Shahin Rafii, Richard T. Lee, Michael P. Verzi, David Redmond, Randy Longman, Kristian Helin, Ramesh A. Shivdasani, Qiao Zhou
Cell Stem Cell. Author manuscript; available in PMC 2023 Jan 6.
Published in final edited form as: Cell Stem Cell. 2022 Jan 6; 29(1): 101–115.e10. Published online 2021 Sep 27. doi: 10.1016/j.stem.2021.09.004
PMCID:
PMC8741647
AbstractArticlePDF–4.5M
14.
UV-induced reduction in Polycomb repression promotes epidermal pigmentation
Meng-Yen Li, Pooja Flora, Hong Pu, Carmit Bar, Jose Silva, Idan Cohen, Phillip M. Galbo, Jr., Hequn Liu, Xufen Yu, Jian Jin, Haruhiko Koseki, John A. D’Orazio, Deyou Zheng, Elena Ezhkova
Dev Cell. Author manuscript; available in PMC 2022 Sep 27.
Published in final edited form as: Dev Cell. 2021 Sep 27; 56(18): 2547–2561.e8. Published online 2021 Sep 1. doi: 10.1016/j.devcel.2021.08.006
PMCID:
PMC8521440
AbstractArticlePDF–3.7M
15.
Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
Hiroki Sugishita, Takashi Kondo, Shinsuke Ito, Manabu Nakayama, Nayuta Yakushiji-Kaminatsui, Eiryo Kawakami, Yoko Koseki, Yasuhide Ohinata, Jafar Sharif, Mio Harachi, Neil P. Blackledge, Robert J. Klose, Haruhiko Koseki
Nat Commun. 2021; 12: 5341. Published online 2021 Sep 9. doi: 10.1038/s41467-021-24894-z
PMCID:
PMC8429492
AbstractArticlePDF–4.0M
16.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
17.
Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos
Zhiyuan Chen, Mohamed Nadhir Djekidel, Yi Zhang
Nat Genet. Author manuscript; available in PMC 2021 Oct 5.
Published in final edited form as: Nat Genet. 2021 Apr; 53(4): 551–563. Published online 2021 Apr 5. doi: 10.1038/s41588-021-00821-2
PMCID:
PMC8092361
AbstractArticlePDF–6.4M
18.
PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway
Wenxian Wang, Hyeyoung Cho, Dongkyeong Kim, Younjung Park, Ji Hwan Moon, Su Jeong Lim, Sung Min Yoon, Michael McCane, Sue A. Aicher, Sangsoo Kim, Ben Emery, Jae W. Lee, Seunghee Lee, Yungki Park, Soo-Kyung Lee
Cell Rep. Author manuscript; available in PMC 2021 Apr 25.
Published in final edited form as: Cell Rep. 2020 Sep 15; 32(11): 108147. doi: 10.1016/j.celrep.2020.108147
PMCID:
PMC8070886
AbstractArticlePDF–4.1M
19.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
20.
Polycomb complexes redundantly maintain epidermal stem cell identity during development
Idan Cohen, Carmit Bar, Hequn Liu, Victor J. Valdes, Dejian Zhao, Phillip M. Galbo, Jr., Jose M. Silva, Haruhiko Koseki, Deyou Zheng, Elena Ezhkova
Genes Dev. 2021 Mar 1; 35(5-6): 354–366. doi: 10.1101/gad.345363.120
PMCID:
PMC7919412
AbstractArticlePDF–9.0M

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