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Items: 1 to 20 of 124

1.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
2.
A proteome-scale map of the SARS-CoV-2–human contactome
Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun
Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z
PMCID:
PMC9849141
AbstractArticlePDF–7.1M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
5.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
6.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
7.
REL and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk
Javeed A. Shah, Alex J. Warr, Andrew D. Graustein, Aparajita Saha, Sarah J. Dunstan, Nguyen T.T. Thuong, Guy E. Thwaites, Maxine Caws, Phan V.K. Thai, Nguyen D. Bang, Tran T.H. Chau, Chiea Chuen Khor, Zheng Li, Martin Hibberd, Xuling Chang, Felicia K. Nguyen, Carlo A. Hernandez, Madison A. Jones, Christopher M. Sassetti, Katherine A. Fitzgerald, Munyaradzi Musvosvi, Anele Gela, Willem A. Hanekom, Mark Hatherill, Thomas J. Scriba, Thomas R. Hawn
J Immunol. Author manuscript; available in PMC 2023 Mar 15.
Published in final edited form as: J Immunol. 2022 Mar 15; 208(6): 1352–1361. Published online 2022 Feb 25. doi: 10.4049/jimmunol.2100671
PMCID:
PMC8917052
AbstractArticlePDF–917K
8.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
NF-κB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK Cells
Yorleny Vicioso, Derek P. Wong, Nand K. Roy, Nayanika Das, Keman Zhang, Parameswaran Ramakrishnan, Reshmi Parameswaran
Front Immunol. 2021; 12: 652786. Published online 2021 Apr 29. doi: 10.3389/fimmu.2021.652786
PMCID:
PMC8116710
AbstractArticlePDF–1.5M
11.
METTL3 restrains papillary thyroid cancer progression via m6A/c-Rel/IL-8-mediated neutrophil infiltration
Jing He, Mingxia Zhou, Jie Yin, Junhu Wan, Jie Chu, Jinlin Jia, Jinxiu Sheng, Chang Wang, Huiqing Yin, Fucheng He
Mol Ther. 2021 May 5; 29(5): 1821–1837. Published online 2021 Jan 21. doi: 10.1016/j.ymthe.2021.01.019
PMCID:
PMC8116572
AbstractArticlePDF–7.2M
12.
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686
PMCID:
PMC7490560
AbstractArticlePDF–8.6M
13.
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits
Izaskun Mitxitorena, Domenico Somma, Jennifer P. Mitchell, Matti Lepistö, Christian Tyrchan, Emma L. Smith, Patrick A. Kiely, Helen Walden, Karen Keeshan, Ruaidhrí J. Carmody
J Biol Chem. 2020 Aug 14; 295(33): 11754–11763. Published online 2020 Jun 25. doi: 10.1074/jbc.RA120.014113
PMCID:
PMC7450122
AbstractArticlePDF–2.5M
14.
The c-Rel-c-Myc Axis Controls Metabolism and Proliferation of Human T Leukemia Cells
Xinyuan Li, George Luo, Ting Li, Honghong Sun, Wei Wang, Emily Eiler, Jason R. Goldsmith, Youhai H. Chen
Mol Immunol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Mol Immunol. 2020 Sep; 125: 115–122. Published online 2020 Jul 10. doi: 10.1016/j.molimm.2020.06.029
PMCID:
PMC7423645
AbstractArticlePDF–894K
15.
A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells
Lucia Mercedes Ruiz-Perera, Johannes Friedrich Wilhelm Greiner, Christian Kaltschmidt, Barbara Kaltschmidt
Cells. 2020 Apr; 9(4): 1037. Published online 2020 Apr 22. doi: 10.3390/cells9041037
PMCID:
PMC7226153
AbstractArticlePDF–7.3M
16.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
17.
Analysis of the REL, BCL11A, and MYCN proto‐oncogenes belonging to the 2p amplicon in chronic lymphocytic leukemia
Clara Deambrogi, Lorenzo De Paoli, Marco Fangazio, Stefania Cresta, Silvia Rasi, Valeria Spina, Valter Gattei, Gianluca Gaidano, Davide Rossi
Am J Hematol. 2010 Jul; 85(7): 541–544. Published online 2010 Apr 21. doi: 10.1002/ajh.21742
PMCID:
PMC7159449
ArticlePDF–829K
18.
Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models
Zishan Wang, Hongtian Dong, Jinghui Wang, Yulu Huang, Xiaoshuang Zhang, Yilin Tang, Qing Li, Zhaolin Liu, Yuanyuan Ma, Jiabin Tong, Li Huang, Jian Fei, Mei Yu, Jian Wang, Fang Huang
Redox Biol. 2020 Feb; 30: 101427. Published online 2020 Jan 13. doi: 10.1016/j.redox.2020.101427
PMCID:
PMC6994410
AbstractArticlePDF–3.9M
19.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
20.
Combined immunodeficiency in a patient with deficiency of c-Rel
Sarah Beaussant-Cohen, Faris Jaber, Michel J. Massaad, Sabrina Weeks, Jennifer Jones, Mohammed F. Alosaimi, Jacqueline Wallace, Waleed Al-Herz, Raif S. Geha, Janet Chou
J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2019 Aug; 144(2): 606–608.e4. Published online 2019 May 16. doi: 10.1016/j.jaci.2019.05.003
PMCID:
PMC6688935
AbstractArticlePDF–781K

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