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Items: 1 to 20 of 38

1.
Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy
Stéphanie Guey, Dominique Hervé, Manoëlle Kossorotoff, Guillaume Ha, Chaker Aloui, Françoise Bergametti, Minh Arnould, Hind Guenou, Jessica Hadjadj, Fanny Dubois Teklali, Florence Riant, Jean-Luc Balligand, Georges Uzan, Bruno O. Villoutreix, Elisabeth Tournier-Lasserve
Hum Genomics. 2023; 17: 24. Published online 2023 Mar 20. doi: 10.1186/s40246-023-00471-x
PMCID:
PMC10026487
AbstractArticlePDF–1.9M
2.
Activation mechanism of human soluble guanylate cyclase by stimulators and activators
Rui Liu, Yunlu Kang, Lei Chen
Nat Commun. 2021; 12: 5492. Published online 2021 Sep 17. doi: 10.1038/s41467-021-25617-0
PMCID:
PMC8448884
AbstractArticlePDF–3.4M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Higher susceptibility to heme oxidation and lower protein stability of the rare α1C517Yβ1 sGC variant associated with moyamoya syndrome
Iraida Sharina, Karina Lezgyieva, Yekaterina Krutsenko, Emil Martin
Biochem Pharmacol. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Biochem Pharmacol. 2021 Feb 8; 186: 114459. Published online 2021 Feb 8. doi: 10.1016/j.bcp.2021.114459
PMCID:
PMC8052303
AbstractArticlePDF–2.3M
5.
Inflammation in the Human Periodontium Induces Downregulation of the α1- and β1-Subunits of the sGC in Cementoclasts
Yüksel Korkmaz, Behrus Puladi, Kerstin Galler, Peer W. Kämmerer, Agnes Schröder, Lina Gölz, Tim Sparwasser, Wilhelm Bloch, Andreas Friebe, James Deschner
Int J Mol Sci. 2021 Jan; 22(2): 539. Published online 2021 Jan 7. doi: 10.3390/ijms22020539
PMCID:
PMC7827426
AbstractArticlePDF–6.7M
6.
Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study
Jian-li Li, Liu-yu Liu, Dong-dong Jiang, Yi-ying Jiang, Guo-qiu Zhou, Dong-can Mo, Man Luo
Lipids Health Dis. 2019; 18: 233. Published online 2019 Dec 28. doi: 10.1186/s12944-019-1177-2
PMCID:
PMC6935057
AbstractArticlePDF–518K
7.
Genetic variation at the coronary artery disease risk locus GUCY1A3 modifies cardiovascular disease prevention effects of aspirin
Kathryn T Hall, Thorsten Kessler, Julie E Buring, Dani Passow, Howard D Sesso, Robert Y L Zee, Paul M Ridker, Daniel I Chasman, Heribert Schunkert
Eur Heart J. 2019 Nov 1; 40(41): 3385–3392. Published online 2019 Jun 22. doi: 10.1093/eurheartj/ehz384
PMCID:
PMC6933533
AbstractArticlePDF–240K
8.
Synergistic mutations in soluble guanylyl cyclase (sGC) reveal a key role for interfacial regions in the sGC activation mechanism
Kenneth C. Childers, Xin-Qiu Yao, Sam Giannakoulias, Joshua Amason, Donald Hamelberg, Elsa D. Garcin
J Biol Chem. 2019 Nov 29; 294(48): 18451–18464. Published online 2019 Oct 23. doi: 10.1074/jbc.RA119.011010
PMCID:
PMC6885636
AbstractArticlePDF–3.3M
9.
Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines
Sonia A. Ronchetti, María Teresa L. Pino, Georgina Cordeiro, Sabrina N. Bollani, Analía G. Ricci, Beatriz H. Duvilanski, Jimena P. Cabilla
Sci Rep. 2019; 9: 14797. Published online 2019 Oct 15. doi: 10.1038/s41598-019-51420-5
PMCID:
PMC6794259
AbstractArticlePDF–5.2M
10.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
11.
Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease
Miriam M. Cortese-Krott, Evanthia Mergia, Christian M. Kramer, Wiebke Lückstädt, Jiangning Yang, Georg Wolff, Christina Panknin, Thilo Bracht, Barbara Sitek, John Pernow, Johannes-Peter Stasch, Martin Feelisch, Doris Koesling, Malte Kelm
Redox Biol. 2018 Apr; 14: 328–337. Published online 2017 Sep 8. doi: 10.1016/j.redox.2017.08.020
PMCID:
PMC5975213
AbstractArticlePDF–1021K
12.
Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling
Connor A. Emdin, Amit V. Khera, Derek Klarin, Pradeep Natarajan, Seyedeh M. Zekavat, Akihiro Nomura, Mary Haas, Krishna Aragam, Diego Ardissino, James G. Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J Bown, Nilesh J Samani, Usman Baber, Jeanette Erdmann, Padhraig Gormley, Aarno Palotie, Nathan O. Stitziel, Namrata Gupta, John Danesh, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan
Circulation. Author manuscript; available in PMC 2019 Jan 16.
Published in final edited form as: Circulation. 2018 Jan 16; 137(3): 222–232. Published online 2017 Oct 5. doi: 10.1161/CIRCULATIONAHA.117.028021
PMCID:
PMC5771958
AbstractArticlePDF–1.3M
13.
Peptide B targets soluble guanylyl cyclase α1 and kills prostate cancer cells
Jun Zhou, Shuai Gao, Chen-Lin Hsieh, Mamata Malla, Lirim Shemshedini
PLoS One. 2017; 12(8): e0184088. Published online 2017 Aug 31. doi: 10.1371/journal.pone.0184088
PMCID:
PMC5578680
AbstractArticlePDF–3.0M
14.
Functional characterization of the GUCY1A3 coronary artery disease risk locus
Thorsten Kessler, Jana Wobst, Bernhard Wolf, Juliane Eckhold, Baiba Vilne, Ronja Hollstein, Simon von Ameln, Tan An Dang, Hendrik B. Sager, Philipp Moritz Rumpf, Redouane Aherrahrou, Adnan Kastrati, Johan L.M. Björkegren, Jeanette Erdmann, Aldons J. Lusis, Mete Civelek, Frank J. Kaiser, Heribert Schunkert
Circulation. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Circulation. 2017 Aug 1; 136(5): 476–489. Published online 2017 May 9. doi: 10.1161/CIRCULATIONAHA.116.024152
PMCID:
PMC5560301
AbstractArticlePDF–2.0M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
17.
Label-free quantification of calcium-sensor targeting to photoreceptor guanylate cyclase and rhodopsin kinase by backscattering interferometry
Stefan Sulmann, Amanda Kussrow, Darryl J. Bornhop, Karl-Wilhelm Koch
Sci Rep. 2017; 7: 45515. Published online 2017 Mar 31. doi: 10.1038/srep45515
PMCID:
PMC5374524
AbstractArticlePDF–777K
18.
Disrupted Nitric Oxide Signaling due to GUCY1A3 Mutations Increases Risk for Moyamoya Disease, Achalasia and Hypertension
Stephanie Wallace, Dong-chuan Guo, Ellen Regalado, Lauren Mellor-Crummey, Michael Banshad, Deborah A. Nickerson, Robert Dauser, Neil Hanchard, Ronit Marom, Emil Martin, Vladimir Berka, Iraida Sharina, Vijeya Ganesan, Dawn Saunders, Shaine Morris, Dianna M. Milewicz
Clin Genet. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Clin Genet. 2016 Oct; 90(4): 351–360. Published online 2016 Feb 18. doi: 10.1111/cge.12739
PMCID:
PMC4949143
AbstractArticlePDF–704K
19.
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
Xiangfeng Lu, Laiyuan Wang, Xu Lin, Jianfeng Huang, C. Charles Gu, Meian He, Hongbing Shen, Jiang He, Jingwen Zhu, Huaixing Li, James E. Hixson, Tangchun Wu, Juncheng Dai, Ling Lu, Chong Shen, Shufeng Chen, Lin He, Zengnan Mo, Yongchen Hao, Xingbo Mo, Xueli Yang, Jianxin Li, Jie Cao, Jichun Chen, Zhongjie Fan, Ying Li, Liancheng Zhao, Hongfan Li, Fanghong Lu, Cailiang Yao, Lin Yu, Lihua Xu, Jianjun Mu, Xianping Wu, Ying Deng, Dongsheng Hu, Weidong Zhang, Xu Ji, Dongshuang Guo, Zhirong Guo, Zhengyuan Zhou, Zili Yang, Renping Wang, Jun Yang, Xiaoyang Zhou, Weili Yan, Ningling Sun, Pingjin Gao, Dongfeng Gu
Hum Mol Genet. 2015 Feb 1; 24(3): 865–874. Published online 2014 Sep 23. doi: 10.1093/hmg/ddu478
PMCID:
PMC4303798
AbstractArticlePDF–408K
20.
HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways
Kelly A Krogh, Nicole Wydeven, Kevin Wickman, Stanley A. Thayer
J Neurochem. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: J Neurochem. 2014 Sep; 130(5): 642–656. Published online 2014 Apr 19. doi: 10.1111/jnc.12724
PMCID:
PMC4141023
AbstractArticlePDF–1.7M

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