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Select item 110113811.

Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival

Shuhan Bu, Aman Singh, Hien C. Nguyen, Bharatsinai Peddi, Kriti Bhatt, Naresh Ravendranathan, Jefferson C. Frisbee, Krishna K. Singh

Int J Mol Sci. 2024 Apr; 25(7): 3913. Published online 2024 Mar 31. doi: 10.3390/ijms25073913

PMCID:: PMC11011381

Abstract Article PDF–2.4M

Select item 109424672.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 109332673.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 107594494.

Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway

Jinqiu Tao, Cailin Xue, Meng Cao, Jiahui Ye, Yulu Sun, Hao Chen, Yinan Guan, Wenjie Zhang, Weijie Zhang, Yongzhong Yao

Breast Cancer Res. 2024; 26: 1. Published online 2024 Jan 2. doi: 10.1186/s13058-023-01758-6

PMCID:: PMC10759449

Abstract Article PDF–7.8M

Select item 107478945.

PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection

Mengwei Xu, Huan Xu, Weiwei Wan, Xiaoqin Jian, Runming Jin, Lin Wang, Jingshi Wang, Gengfu Xiao, Leike Zhang, Hongbo Chen, Yuxi Wen

Viruses. 2023 Dec; 15(12): 2343. Published online 2023 Nov 29. doi: 10.3390/v15122343

PMCID:: PMC10747894

Abstract Article PDF–8.0M

Select item 106277866.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 105018467.

LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17

Chanjiao Yao, Lingjuan Zeng, Qin Liu, Xiaoxin Qiu, Chunyan Chen

Breast J. 2023; 2023: 3970444. Published online 2023 Sep 7. doi: 10.1155/2023/3970444

PMCID:: PMC10501846

Abstract Article PDF–4.3M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516159.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1014884310.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 1010367811.

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M. Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Sci China Life Sci. 2023 Apr 14 : 1–19. doi: 10.1007/s11427-023-2316-2 [Epub ahead of print]

PMCID:: PMC10103678

Abstract Article PDF–2.4M

Select item 1006198212.

Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy

Zewei Tu, Chong Wang, Qing Hu, Chuming Tao, Zhansheng Fang, Li Lin, Kunjian Lei, Min Luo, Yilei Sheng, Xiaoyan Long, Jingying Li, Lei Wu, Kai Huang, Xingen Zhu

J Exp Clin Cancer Res. 2023; 42: 77. Published online 2023 Mar 30. doi: 10.1186/s13046-023-02640-1

PMCID:: PMC10061982

Abstract Article PDF–15M

Select item 1000855613.

PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma

Lichun Kang, Dekun Wang, Tianyu Shen, Xuan Liu, Bo Dai, Donghui Zhou, Huan Shen, Junbo Gong, Gang Li, Yuanjing Hu, Peng Wang, Xue Mi, Yuying Zhang, Xiaoyue Tan

Cell Death Dis. 2023 Mar; 14(3): 193. Published online 2023 Mar 11. doi: 10.1038/s41419-023-05719-x

PMCID:: PMC10008556

Abstract Article PDF–4.6M

Select item 985197314.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 981686815.

PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle

Chien-Hsing Lee, Chi-Fu Chiang, Fu-Huang Lin, Feng-Chih Kuo, Sheng-Chiang Su, Chia-Luen Huang, Peng-Fei Li, Jhih-Syuan Liu, Chieh-Hua Lu, Chang-Hsun Hsieh, Yi-Jen Hung, Yi-Shing Shieh

Front Endocrinol (Lausanne) 2022; 13: 1053882. Published online 2022 Dec 23. doi: 10.3389/fendo.2022.1053882

PMCID:: PMC9816868

Abstract Article PDF–3.1M

Select item 981605916.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

Select item 979798817.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 979580718.

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2

Annarita Miluzio, Alessandro Cuomo, Chiara Cordiglieri, Lorena Donnici, Elisa Pesce, Mauro Bombaci, Matteo Conti, Alessandra Fasciani, Luigi Terracciano, Lara Manganaro, Mirco Toccafondi, Alessandra Scagliola, Stefania Oliveto, Sara Ricciardi, Renata Grifantini, Raffaele De Francesco, Sergio Abrignani, Nicola Manfrini, Stefano Biffo

eBioMedicine. 2023 Jan; 87: 104390. Published online 2022 Dec 28. doi: 10.1016/j.ebiom.2022.104390

PMCID:: PMC9795807

Abstract Article PDF–4.6M

Select item 962912119.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 956995520.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

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