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Select item 105238661.

Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis

Jaewon You, Michael D. Reilly, Mahmoud Eljalby, Rohan Bareja, Maftuna Yusupova, Nikki S. Vyas, Jakyung Bang, Wanhong Ding, Garrett Desman, Lloyd S. Miller, Olivier Elemento, Richard D. Granstein, Jonathan H. Zippin

Exp Dermatol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Exp Dermatol. 2023 Jul; 32(7): 1051–1062. Published online 2023 Apr 11. doi: 10.1111/exd.14811

PMCID:: PMC10523866

Abstract Article PDF–953K

Select item 103987452.

Carbonic Anhydrase Inhibitor Modulation of Intraocular Pressure Is Independent of Soluble Adenylyl Cyclase

Shakarr V. Wiggins, Ryan Schreiner, Jacob Ferreira, Alan D. Marmorstein, Lonny R. Levin, Jochen Buck

J Ocul Pharmacol Ther. June 2023; 39(5): 317–323. Published online 2023 Jun 12. doi: 10.1089/jop.2022.0180

PMCID:: PMC10398745

Abstract Article PDF–356K

Select item 101604833.

In vivo characterization of sAC null sperm

Carla Ritagliati, Sylvia Ayoub, Melanie Balbach, Jochen Buck, Lonny R. Levin

Front Cell Dev Biol. 2023; 11: 1134051. Published online 2023 Apr 21. doi: 10.3389/fcell.2023.1134051

PMCID:: PMC10160483

Abstract Article PDF–2.2M

Select item 85058954.

Conserved Mechanism of Bicarbonate-Induced Sensitization of CatSper Channels in Human and Mouse Sperm

Juan J. Ferreira, Pascale Lybaert, Lis C. Puga-Molina, Celia M. Santi

Front Cell Dev Biol. 2021; 9: 733653. Published online 2021 Sep 28. doi: 10.3389/fcell.2021.733653

PMCID:: PMC8505895

Abstract Article PDF–4.3M

Select item 81256235.

Effect of Soluble Adenylyl Cyclase (ADCY10) Inhibitors on the LH-Stimulated cAMP Synthesis in Mltc-1 Leydig Cell Line

Thi Mong Diep Nguyen, Laura Filliatreau, Danièle Klett, Nong Van Hai, Nguyen Thuy Duong, Yves Combarnous

Int J Mol Sci. 2021 May; 22(9): 4641. Published online 2021 Apr 28. doi: 10.3390/ijms22094641

PMCID:: PMC8125623

Abstract Article PDF–12M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73136197.

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Nonalcoholic Steatohepatitis

Xiaobo Wang, Bishuang Cai, Xiaoming Yang, Oluwatoni O. Sonubi, Ze Zheng, Rajasekhar Ramakrishnan, Hongxue Shi, Luca Valenti, Utpal B. Pajvani, Jaspreet Sandhu, Rodney E. Infante, Arun Radhakrishnan, Douglas F. Covey, Kun-Liang Guan, Jochen Buck, Lonny R. Levin, Peter Tontonoz, Robert F. Schwabe, Ira Tabas

Cell Metab. Author manuscript; available in PMC 2021 May 5.

Published in final edited form as: Cell Metab. 2020 May 5; 31(5): 969–986.e7. Published online 2020 Apr 6. doi: 10.1016/j.cmet.2020.03.010

PMCID:: PMC7313619

Abstract Article PDF–1.4M

Select item 72695728.

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α

M. Ahsan Siraj, Dhanwantee Mundil, Sanja Beca, Abdul Momen, Eric A. Shikatani, Talat Afroze, Xuetao Sun, Ying Liu, Siavash Ghaffari, Warren Lee, Michael B. Wheeler, Gordon Keller, Peter Backx, Mansoor Husain

J Clin Invest. 2020 Mar 2; 130(3): 1392–1404. Published online 2020 Jan 27. doi: 10.1172/JCI99934

PMCID:: PMC7269572

Abstract Article PDF–1.4M

Select item 66704679.

Soluble Adenylyl Cyclase Is Not Required for Axon Guidance to Netrin-1

Simon W. Moore, Karen Lai Wing Sun, Fang Xie, Philip A. Barker, Marco Conti, Timothy E. Kennedy

J Neurosci. 2008 Apr 9; 28(15): 3920–3924. doi: 10.1523/JNEUROSCI.0547-08.2008

PMCID:: PMC6670467

Abstract Article PDF–296K

Select item 582134510.

Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload

Ilona Schirmer, Tippaporn Bualeong, Heidi Budde, Diana Cimiotti, Avinash Appukuttan, Nicole Klein, Philip Steinwascher, Peter Reusch, Andreas Mügge, Rainer Meyer, Yury Ladilov, Kornelia Jaquet

PLoS One. 2018; 13(2): e0192322. Published online 2018 Feb 21. doi: 10.1371/journal.pone.0192322

PMCID:: PMC5821345

Abstract Article PDF–12M

Select item 542376711.

PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling

Stefania Monterisi, Miguel J Lobo, Craig Livie, John C Castle, Michael Weinberger, George Baillie, Nicoletta C Surdo, Nshunge Musheshe, Alessandra Stangherlin, Eyal Gottlieb, Rory Maizels, Mario Bortolozzi, Massimo Micaroni, Manuela Zaccolo

eLife. 2017; 6: e21374. Published online 2017 May 2. doi: 10.7554/eLife.21374

PMCID:: PMC5423767

Abstract Article PDF–4.1M

Select item 505311612.

Soluble Adenylyl Cyclase Is Required for Retinal Ganglion Cell and Photoreceptor Differentiation

Peter X. Shaw, Jiahua Fang, Alan Sang, Yan Wang, Michael S. Kapiloff, Jeffrey L. Goldberg

Invest Ophthalmol Vis Sci. 2016 Sep; 57(11): 5083–5092. doi: 10.1167/iovs.16-19465

PMCID:: PMC5053116

Abstract Article PDF–1.9M

Select item 503734213.

Soluble adenylyl cyclase is essential for proper lysosomal acidification

Nawreen Rahman, Lavoisier Ramos-Espiritu, Teresa A. Milner, Jochen Buck, Lonny R. Levin

J Gen Physiol. 2016 Oct; 148(4): 325–339. doi: 10.1085/jgp.201611606

PMCID:: PMC5037342

Abstract Article PDF–3.3M

Select item 502433914.

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models

Felipe A. Navarrete, Antonio Alvau, Hoi Chang Lee, Lonny R. Levin, Jochen Buck, Patricia Martin-De Leon, Celia M. Santi, Dario Krapf, Jesse Mager, Rafael A. Fissore, Ana M. Salicioni, Alberto Darszon, Pablo E. Visconti

Sci Rep. 2016; 6: 33589. Published online 2016 Sep 15. doi: 10.1038/srep33589

PMCID:: PMC5024339

Abstract Article PDF–1.0M

Select item 449341615.

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration

Richard L. Watson, Jochen Buck, Lonny R. Levin, Ryan C. Winger, Jing Wang, Hisashi Arase, William A. Muller

J Exp Med. 2015 Jun 29; 212(7): 1021–1041. doi: 10.1084/jem.20150354

PMCID:: PMC4493416

Abstract Article PDF–4.6M

Select item 429154516.

A Soluble Adenylyl Cyclase Form Targets to Axonemes and Rescues Beat Regulation in Soluble Adenylyl Cyclase Knockout Mice

Xi Chen, Nathalie Baumlin, Jochen Buck, Lonny R. Levin, Nevis Fregien, Matthias Salathe

Am J Respir Cell Mol Biol. 2014 Dec; 51(6): 750–760. doi: 10.1165/rcmb.2013-0542OC

PMCID:: PMC4291545

Abstract Article PDF–1.7M

Select item 385327917.

Compartmentalization of Distinct cAMP Signaling Pathways in Mammalian Sperm

Eva Wertheimer, Dario Krapf, José L. de la Vega-Beltran, Claudia Sánchez-Cárdenas, Felipe Navarrete, Douglas Haddad, Jessica Escoffier, Ana M. Salicioni, Lonny R. Levin, Jochen Buck, Jesse Mager, Alberto Darszon, Pablo E. Visconti

J Biol Chem. 2013 Dec 6; 288(49): 35307–35320. Published online 2013 Oct 15. doi: 10.1074/jbc.M113.489476

PMCID:: PMC3853279

Abstract Article PDF–1.9M

Select item 382917418.

CO₂/HCO₃⁻- and Calcium-regulated Soluble Adenylyl Cyclase as a Physiological ATP Sensor

Jonathan H. Zippin, Yanqiu Chen, Susanne G. Straub, Kenneth C. Hess, Ana Diaz, Dana Lee, Patrick Tso, George G. Holz, Geoffrey W. G. Sharp, Lonny R. Levin, Jochen Buck

J Biol Chem. 2013 Nov 15; 288(46): 33283–33291. Published online 2013 Oct 7. doi: 10.1074/jbc.M113.510073

Correction in:: J Biol Chem. 2014 May 2; 289(18): 12679.

PMCID:: PMC3829174

Abstract Article PDF–1.7M

Select item 367934219.

Neuronal Expression of Soluble Adenylyl Cyclase in the Mammalian Brain

Jonathan Chen, Jennifer Martinez, Teresa A. Milner, Jochen Buck, Lonny R. Levin

Brain Res. Author manuscript; available in PMC 2014 Jun 26.

Published in final edited form as: Brain Res. 2013 Jun 26; 1518: 1–8. Published online 2013 Apr 21. doi: 10.1016/j.brainres.2013.04.027

PMCID:: PMC3679342

Abstract Article PDF–4.0M

Select item 363099820.

Metabolic Communication between Astrocytes and Neurons via Bicarbonate-Responsive Soluble Adenylyl Cyclase

Hyun B. Choi, Grant R.J. Gordon, Ning Zhou, Chao Tai, Ravi L. Rungta, Jennifer Martinez, Teresa A. Milner, Jae K. Ryu, James G. McLarnon, Martin Tresguerres, Lonny R. Levin, Jochen Buck, Brian A. MacVicar

Neuron. Author manuscript; available in PMC 2013 Apr 19.

Published in final edited form as: Neuron. 2012 Sep 20; 75(6): 1094–1104. doi: 10.1016/j.neuron.2012.08.032

PMCID:: PMC3630998

Abstract Article PDF–2.4M

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