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Items: 1 to 20 of 22

1.
LHFPL5 is a key element in force transmission from the tip link to the hair cell mechanotransducer channel
Maryline Beurg, Evan Travis Schwalbach, Robert Fettiplace
Proc Natl Acad Sci U S A. 2024 Jan 16; 121(3): e2318270121. Published online 2024 Jan 9. doi: 10.1073/pnas.2318270121
PMCID:
PMC10801851
AbstractArticlePDF–2.3M
2.
The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
Xufeng Qiu, Xiaoping Liang, Jose P. Llongueras, Christopher Cunningham, Ulrich Müller
Cell Rep. Author manuscript; available in PMC 2023 Jul 12.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112245. Published online 2023 Mar 13. doi: 10.1016/j.celrep.2023.112245
PMCID:
PMC10337519
AbstractArticlePDF–3.2M
3.
The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells
Robert Fettiplace, David N. Furness, Maryline Beurg
Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2210849119. Published online 2022 Oct 3. doi: 10.1073/pnas.2210849119
PMCID:
PMC9564823
AbstractArticlePDF–2.0M
4.
Alternative Splicing of Three Genes Encoding Mechanotransduction-Complex Proteins in Auditory Hair Cells
Zijing Zhou, Xiaojie Yu, Biaobin Jiang, Wanying Feng, Ye Tian, Zhiyong Liu, Jiguang Wang, Pingbo Huang
eNeuro. 2021 Jan-Feb; 8(1): ENEURO.0381-20.2020. Prepublished online 2021 Jan 28. Published online 2021 Feb 23. doi: 10.1523/ENEURO.0381-20.2020
PMCID:
PMC7920537
AbstractArticlePDF–2.4M
5.
Inhibition of a transcriptional repressor rescues hearing in a splicing factor–deficient mouse
Yoko Nakano, Susan Wiechert, Bernd Fritzsch, Botond Bánfi
Life Sci Alliance. 2020 Dec; 3(12): e202000841. Published online 2020 Oct 21. doi: 10.26508/lsa.202000841
PMCID:
PMC7652395
AbstractArticlePDF–3.4M
6.
TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice
Shuang Liu, Shufeng Wang, Linzhi Zou, Jie Li, Chenmeng Song, Jiaofeng Chen, Qun Hu, Lian Liu, Pingbo Huang, Wei Xiong
eLife. 2019; 8: e47441. Published online 2019 Oct 29. doi: 10.7554/eLife.47441
PMCID:
PMC6853638
AbstractArticlePDF–2.8M
7.
Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System
Shuohao Sun, Travis Babola, Gabriela Pregernig, Kathy So, Matthew Nguyen, Michael Su, Adam Palermo, Dwight E. Bergles, Joseph C. Burns, Ulrich Müller
Cell. Author manuscript; available in PMC 2019 Aug 23.
Published in final edited form as: Cell. 2018 Aug 23; 174(5): 1247–1263.e15. Published online 2018 Aug 2. doi: 10.1016/j.cell.2018.07.008
PMCID:
PMC6429032
AbstractArticlePDF–1.7M
8.
A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development
Basile Tarchini, Chantal Longo-Guess, Cong Tian, Abigail L.D. Tadenev, Nicholas Devanney, Kenneth R. Johnson
Dev Biol. Author manuscript; available in PMC 2019 Nov 15.
Published in final edited form as: Dev Biol. 2018 Nov 15; 443(2): 153–164. Published online 2018 Sep 11. doi: 10.1016/j.ydbio.2018.09.011
PMCID:
PMC6214362
AbstractArticlePDF–1.9M
9.
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
Jingpeng Ge, Johannes Elferich, April Goehring, Huaying Zhao, Peter Schuck, Eric Gouaux
eLife. 2018; 7: e38770. Published online 2018 Aug 2. doi: 10.7554/eLife.38770
PMCID:
PMC6092121
AbstractArticlePDF–5.4M
10.
Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15
Shanthini Mahendrasingam, Robert Fettiplace, Kumar N. Alagramam, Ellen Cross, David N. Furness
PLoS One. 2017; 12(10): e0185285. Published online 2017 Oct 25. doi: 10.1371/journal.pone.0185285
PMCID:
PMC5656302
AbstractArticlePDF–39M
11.
The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells
Christopher L Cunningham, Zizhen Wu, Aria Jafari, Bo Zhao, Kat Schrode, Sarah Harkins-Perry, Amanda Lauer, Ulrich Müller
eLife. 2017; 6: e24318. Published online 2017 May 15. doi: 10.7554/eLife.24318
Correction in:
eLife. 2017; 6: e33307.
PMCID:
PMC5462538
AbstractArticlePDF–16M
12.
Novel function of LHFPL2 in female and male distal reproductive tract development
Fei Zhao, Jun Zhou, Rong Li, Elizabeth A. Dudley, Xiaoqin Ye
Sci Rep. 2016; 6: 23037. Published online 2016 Mar 11. doi: 10.1038/srep23037
PMCID:
PMC4786858
AbstractArticlePDF–2.0M
13.
Subunit determination of the conductance of hair-cell mechanotransducer channels
Maryline Beurg, Wei Xiong, Bo Zhao, Ulrich Müller, Robert Fettiplace
Proc Natl Acad Sci U S A. 2015 Feb 3; 112(5): 1589–1594. Published online 2014 Dec 30. doi: 10.1073/pnas.1420906112
PMCID:
PMC4321290
AbstractArticlePDF–966K
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
TMHS is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells
Wei Xiong, Nicolas Grillet, Heather M. Elledge, Thomas F.J. Wagner, Bo Zhao, Kenneth R. Johnson, Piotr Kazmierczak, Ulrich Müller
Cell. Author manuscript; available in PMC 2013 Dec 7.
Published in final edited form as: Cell. 2012 Dec 7; 151(6): 1283–1295. doi: 10.1016/j.cell.2012.10.041
PMCID:
PMC3522178
AbstractArticlePDF–2.7M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation
Chantal M. Longo-Guess, Leona H. Gagnon, Bernd Fritzsch, Kenneth R. Johnson
Mamm Genome. Author manuscript; available in PMC 2009 Jan 1.
Published in final edited form as: Mamm Genome. 2007 Sep; 18(9): 646–656. Published online 2007 Sep 18. doi: 10.1007/s00335-007-9049-x
PMCID:
PMC2613174
AbstractArticlePDF–1.0M
18.
A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice
Chantal M. Longo-Guess, Leona H. Gagnon, Susan A. Cook, Jian Wu, Qing Y. Zheng, Kenneth R. Johnson
Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7894–7899. Published online 2005 May 19. doi: 10.1073/pnas.0500760102
PMCID:
PMC1142366
AbstractArticlePDF–516K
19.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
20.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M

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