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Select item 108059761.

Ribosomal protein L24 mediates mammalian microRNA processing in an evolutionarily conserved manner

Yonat Tzur, Serafima Dubnov, Nimrod Madrer, Adi Bar, Bettina Nadorp, Nibha Mishra, Paul Heppenstall, Estelle R. Bennett, David S. Greenberg, Katarzyna Winek, Hermona Soreq

Cell Mol Life Sci. 2024 Dec; 81(1): 55. Published online 2024 Jan 23. doi: 10.1007/s00018-023-05088-w

PMCID:: PMC10805976

Abstract Article PDF–3.2M

Select item 101499302.

Enhanced protein synthesis is a defining requirement for neonatal B cell development

Hugo Åkerstrand, Elena Boldrin, Giorgia Montano, Stijn Vanhee, Karin Olsson, Niklas Krausse, Stefano Vergani, Maciej Cieśla, Cristian Bellodi, Joan Yuan

Front Immunol. 2023; 14: 1130930. Published online 2023 Apr 17. doi: 10.3389/fimmu.2023.1130930

PMCID:: PMC10149930

Abstract Article PDF–4.3M

Select item 97081163.

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24^Bst Mouse

John R.P. Knight, Christopher G. Proud, Giovanna Mallucci, Tobias von der Haar, C. Mark Smales, Anne E. Willis, Owen J. Sansom

J Invest Dermatol. 2022 Dec; 142(12): 3346–3348.e1. doi: 10.1016/j.jid.2022.06.019

PMCID:: PMC9708116

Article

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 88972335.

In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration

Yuemeng Jia, Lin Li, Yu-Hsuan Lin, Purva Gopal, Shunli Shen, Kejin Zhou, Xueliang Yu, Tripti Sharma, Yu Zhang, Daniel J. Siegwart, Joseph M. Ready, Hao Zhu

Cell Stem Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell Stem Cell. 2022 Mar 3; 29(3): 372–385.e8. Published online 2022 Jan 31. doi: 10.1016/j.stem.2022.01.001

PMCID:: PMC8897233

Abstract Article PDF–3.9M

Select item 87488736.

Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy

Tiffany Chern, Annita Achilleos, Xuefei Tong, Matthew C. Hill, Alexander B. Saltzman, Lucas C. Reineke, Arindam Chaudhury, Swapan K. Dasgupta, Yushi Redhead, David Watkins, Joel R. Neilson, Perumal Thiagarajan, Jeremy B. A. Green, Anna Malovannaya, James F. Martin, David S. Rosenblatt, Ross A. Poché

Nat Commun. 2022; 13: 134. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27759-7

PMCID:: PMC8748873

Abstract Article PDF–11M

Select item 86681887.

Rpl24^Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K

John RP Knight, Nikola Vlahov, David M Gay, Rachel A Ridgway, William James Faller, Christopher Proud, Giovanna R Mallucci, Tobias von der Haar, Christopher Mark Smales, Anne E Willis, Owen J Sansom

eLife. 2021; 10: e69729. Published online 2021 Dec 13. doi: 10.7554/eLife.69729

PMCID:: PMC8668188

Abstract Article PDF–1.8M

Select item 82666178.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 82623549.

mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformation

Sujata Jana, Rucha Deo, Rowan P. Hough, Yuzhen Liu, Jessie L. Horn, Jonathan L. Wright, Hung-Ming Lam, Kevin R. Webster, Gary G. Chiang, Nahum Sonenberg, Andrew C. Hsieh

JCI Insight. 2021 Jun 8; 6(11): e144920. Published online 2021 Jun 8. doi: 10.1172/jci.insight.144920

PMCID:: PMC8262354

Abstract Article PDF–9.9M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 781594211.

Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis

Jeffrey A. Magee, Robert A.J. Signer

Stem Cell Reports. 2021 Jan 12; 16(1): 20–28. Published online 2021 Jan 12. doi: 10.1016/j.stemcr.2020.11.017

PMCID:: PMC7815942

Abstract Article PDF–2.5M

Select item 741599112.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 723606013.

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell

iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132

PMCID:: PMC7236060

Abstract Article PDF–6.1M

Select item 700449114.

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

Lorena Hidalgo San Jose, Mary Jean Sunshine, Christopher H. Dillingham, Bernadette A. Chua, Miriama Kruta, Yuning Hong, Danny M. Hatters, Robert A.J. Signer

Cell Rep. Author manuscript; available in PMC 2020 Feb 6.

Published in final edited form as: Cell Rep. 2020 Jan 7; 30(1): 69–80.e6. doi: 10.1016/j.celrep.2019.12.003

PMCID:: PMC7004491

Abstract Article PDF–1.9M

Select item 699392515.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 669277016.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 665555117.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 655001518.

Lin28-mediated temporal promotion of protein synthesis is crucial for neural progenitor cell maintenance and brain development in mice

Stephanie Herrlinger, Qiang Shao, Mei Yang, Qing Chang, Yang Liu, Xiaohan Pan, Hang Yin, Li-Wei Xie, Jian-Fu Chen

Development. 2019 May 15; 146(10): dev173765. Published online 2019 May 28. doi: 10.1242/dev.173765

PMCID:: PMC6550015

Abstract Article

Select item 629804019.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 593680020.

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis

Yves Mugabo, Mina Sadeghi, Nancy N. Fang, Thibault Mayor, Gareth E. Lim

J Biol Chem. 2018 May 4; 293(18): 6736–6750. Published online 2018 Mar 12. doi: 10.1074/jbc.M117.816272

PMCID:: PMC5936800

Abstract Article PDF–2.4M

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