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Select item 88535261.

Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death

Abby R. Kroken, Naren Gajenthra Kumar, Timothy L. Yahr, Benjamin E. Smith, Vincent Nieto, Hart Horneman, David J. Evans, Suzanne M. J. Fleiszig

PLoS Pathog. 2022 Feb; 18(2): e1010306. Published online 2022 Feb 7. doi: 10.1371/journal.ppat.1010306

PMCID:: PMC8853526

Abstract Article PDF–5.6M

Select item 78574342.

Pseudomonas aeruginosa survives in epithelia by ExoS‐mediated inhibition of autophagy and mTOR

Lang Rao, Indhira De La Rosa, Yi Xu, Youbao Sha, Abhisek Bhattacharya, Michael J Holtzman, Brian E Gilbert, N Tony Eissa

EMBO Rep. 2021 Feb 3; 22(2): e50613. Published online 2020 Dec 20. doi: 10.15252/embr.202050613

PMCID:: PMC7857434

Abstract Article PDF–2.7M

Select item 66597103.

High frequency of the exoU+/exoS+ genotype associated with multidrug-resistant “high-risk clones” of Pseudomonas aeruginosa clinical isolates from Peruvian hospitals

Gertrudis Horna, Catherine Amaro, Aida Palacios, Humberto Guerra, Joaquim Ruiz

Sci Rep. 2019; 9: 10874. Published online 2019 Jul 26. doi: 10.1038/s41598-019-47303-4

PMCID:: PMC6659710

Abstract Article PDF–1.5M

Select item 61458934.

Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity

Amber Kaminski, Kajal H. Gupta, Josef W. Goldufsky, Ha Won Lee, Vineet Gupta, Sasha H. Shafikhani

Sci Rep. 2018; 8: 14047. Published online 2018 Sep 19. doi: 10.1038/s41598-018-32491-2

PMCID:: PMC6145893

Abstract Article PDF–12M

Select item 59303085.

The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression

Abby R. Kroken, Camille K. Chen, David J. Evans, Timothy L. Yahr, Suzanne M. J. Fleiszig

mBio. 2018 May-Jun; 9(3): e00668-18. Published online 2018 May 1. doi: 10.1128/mBio.00668-18

PMCID:: PMC5930308

Abstract Article PDF–5.2M

Select item 58890056.

Epithelial cell lysates induce ExoS expression and secretion by Pseudomonas aeruginosa

Victoria Hritonenko, Matteo Metruccio, David Evans, Suzanne Fleiszig

FEMS Microbiol Lett. 2018 Apr; 365(8): fny053. Published online 2018 Mar 6. doi: 10.1093/femsle/fny053

PMCID:: PMC5889005

Abstract Article PDF–796K

Select item 44748357.

The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia

Stephanie M. Rangel, Maureen H. Diaz, Claire A. Knoten, Angelica Zhang, Alan R. Hauser

PLoS Pathog. 2015 Jun; 11(6): e1004945. Published online 2015 Jun 19. doi: 10.1371/journal.ppat.1004945

Correction in:: PLoS Pathog. 2015 Sep; 11(9): e1005163.

PMCID:: PMC4474835

Abstract Article PDF–15M

Select item 37768608.

Pseudomonas aeruginosa Utilizes the Type III Secreted Toxin ExoS to Avoid Acidified Compartments within Epithelial Cells

Susan R. Heimer, David J. Evans, Michael E. Stern, Joseph T. Barbieri, Timothy Yahr, Suzanne M. J. Fleiszig

PLoS One. 2013; 8(9): e73111. Published online 2013 Sep 18. doi: 10.1371/journal.pone.0073111

PMCID:: PMC3776860

Abstract Article PDF–1.8M

Select item 32735779.

ExoS and ExoT ADP-ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival

Yan Sun, Mausita Karmakar, Patricia R. Taylor, Arne Rietsch, Eric Pearlman

J Immunol. Author manuscript; available in PMC 2013 Feb 15.

Published in final edited form as: J Immunol. 2012 Feb 15; 188(4): 1884–1895. Published online 2012 Jan 16. doi: 10.4049/jimmunol.1102148

PMCID:: PMC3273577

Abstract Article PDF–1.2M

Select item 297635810.

The ADP-Ribosylation Domain of Pseudomonas aeruginosa ExoS Is Required for Membrane Bleb Niche Formation and Bacterial Survival within Epithelial Cells

Annette A. Angus, David J. Evans, Joseph T. Barbieri, Suzanne M. J. Fleiszig

Infect Immun. 2010 Nov; 78(11): 4500–4510. Published online 2010 Aug 23. doi: 10.1128/IAI.00417-10

PMCID:: PMC2976358

Abstract Article PDF–4.6M

Select item 297634111.

Translocation of Pseudomonas aeruginosa from the Intestinal Tract Is Mediated by the Binding of ExoS to an Na,K-ATPase Regulator, FXYD3

Jun Okuda, Naoki Hayashi, Masashi Okamoto, Shinji Sawada, Shu Minagawa, Yoshitaka Yano, Naomasa Gotoh

Infect Immun. 2010 Nov; 78(11): 4511–4522. Published online 2010 Aug 30. doi: 10.1128/IAI.00428-10

PMCID:: PMC2976341

Abstract Article PDF–2.1M

Select item 290791412.

Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3

Lubna Yasmin, Jeffrey L. Veesenmeyer, Maureen H Diaz, Matthew S. Francis, Ruth H Palmer, Alan R Hauser, Bengt Hallberg

Biochem J. Author manuscript; available in PMC 2011 Apr 15.

Published in final edited form as: Biochem J. 2010 Mar 29; 427(2): 217–224. Published online 2010 Mar 29. doi: 10.1042/BJ20100043

PMCID:: PMC2907914

Abstract Article PDF–496K

Select item 268650813.

Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes

Geoffrey L. Winsor, Thea Van Rossum, Raymond Lo, Bhavjinder Khaira, Matthew D. Whiteside, Robert E. W. Hancock, Fiona S. L. Brinkman

Nucleic Acids Res. 2009 Jan; 37(Database issue): D483–D488. Published online 2008 Oct 31. doi: 10.1093/nar/gkn861

PMCID:: PMC2686508

Abstract Article PDF–1.3M

Select item 229325014.

ExoS Controls the Cell Contact-Mediated Switch to Effector Secretion in Pseudomonas aeruginosa

Michelle Cisz, Pei-Chung Lee, Arne Rietsch

J Bacteriol. 2008 Apr; 190(8): 2726–2738. Published online 2007 Nov 26. doi: 10.1128/JB.01553-07

PMCID:: PMC2293250

Abstract Article PDF–813K

Select item 163624115.

Defining the Pseudomonas aeruginosa SOS Response and Its Role in the Global Response to the Antibiotic Ciprofloxacin

Ryan T. Cirz, Bryan M. O'Neill, Jennifer A. Hammond, Steven R. Head, Floyd E. Romesberg

J Bacteriol. 2006 Oct; 188(20): 7101–7110. doi: 10.1128/JB.00807-06

PMCID:: PMC1636241

Abstract Article PDF–115K

Select item 119600716.

Cystic Fibrosis Sputum Supports Growth and Cues Key Aspects of Pseudomonas aeruginosa Physiology

Kelli L. Palmer, Lauren M. Mashburn, Pradeep K. Singh, Marvin Whiteley

J Bacteriol. 2005 Aug; 187(15): 5267–5277. doi: 10.1128/JB.187.15.5267-5277.2005

PMCID:: PMC1196007

Abstract Article PDF–175K

Select item 116951017.

A Cystic Fibrosis Epidemic Strain of Pseudomonas aeruginosa Displays Enhanced Virulence and Antimicrobial Resistance

Prabhakar Salunkhe, Catherine H. M. Smart, J. Alun W. Morgan, Stavroula Panagea, Martin J. Walshaw, C. Anthony Hart, Robert Geffers, Burkhard Tümmler, Craig Winstanley

J Bacteriol. 2005 Jul; 187(14): 4908–4920. doi: 10.1128/JB.187.14.4908-4920.2005

PMCID:: PMC1169510

Abstract Article PDF–145K

Select item 111205818.

Quorum Sensing Negatively Controls Type III Secretion Regulon Expression in Pseudomonas aeruginosa PAO1

Sophie Bleves, Chantal Soscia, Patricia Nogueira-Orlandi, Andrée Lazdunski, Alain Filloux

J Bacteriol. 2005 Jun; 187(11): 3898–3902. doi: 10.1128/JB.187.11.3898-3902.2005

PMCID:: PMC1112058

Abstract Article PDF–235K

Select item 111184719.

Effect of Anaerobiosis and Nitrate on Gene Expression in Pseudomonas aeruginosa

M. J. Filiatrault, V. E. Wagner, D. Bushnell, C. G. Haidaris, B. H. Iglewski, L. Passador

Infect Immun. 2005 Jun; 73(6): 3764–3772. doi: 10.1128/IAI.73.6.3764-3772.2005

PMCID:: PMC1111847

Abstract Article PDF–69K

Select item 106493020.

Role of the Type III Secreted Exoenzymes S, T, and Y in Systemic Spread of Pseudomonas aeruginosa PAO1 In Vivo

Russell E. Vance, Arne Rietsch, John J. Mekalanos

Infect Immun. 2005 Mar; 73(3): 1706–1713. doi: 10.1128/IAI.73.3.1706-1713.2005

PMCID:: PMC1064930

Abstract Article PDF–118K

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PMC Links for GEO Profiles (Select 42857443) (24)
PMC
Conserved Domain Links for Protein (Select 523498694) (1)
Conserved Domains
GSE174451[Accession] (11)
GEO DataSets
PREDICTED: Papio anubis CD72 molecule (CD72), transcript variant X2, mRNA
PREDICTED: Papio anubis CD72 molecule (CD72), transcript variant X2, mRNA
gi|1777272757|ref|XM_021927404.2|

Nucleotide
Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4...
Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4933437D13 product:reelin, full insert sequence
gi|12856177|dbj|AK017094.1|

Nucleotide

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