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Items: 1 to 20 of 91

1.
Renal ischaemia-reperfusion injury is promoted by transcription factor NF-kB p65, which inhibits TRPC6 expression by activating miR-150
Shuangyu Li, Qiubo Ma, Zengwei Ma, Ying Shi, Xiaoyan Yu, Baohua Gu, Shanshan Sun, Chunlei Yu, Lei Pang
Clin Hemorheol Microcirc. 2024; 86(3): 369–382. Prepublished online 2023 Nov 10. Published online 2024 Apr 10. doi: 10.3233/CH-231979
PMCID:
PMC11091637
AbstractArticlePDF–742K
2.
TRPC6 N338S is a gain-of-function mutant identified in patient with doxorubicin-induced cardiotoxicity
Tong Lu, Xiaojing Sun, Brian M. Necela, Hon-Chi Lee, Nadine Norton
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2024 Feb 10.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1; 1868(11): 166505. Published online 2022 Jul 23. doi: 10.1016/j.bbadis.2022.166505
PMCID:
PMC10858733
AbstractArticlePDF–1.3M
3.
TRPC6 Deletion Enhances eNOS Expression and Reduces LPS—Induced Acute Lung Injury
Mengyuan Wang, Xingfang Zhang, Juan Guo, Shangze Yang, Fang Yang, Xingjuan Chen
Int J Mol Sci. 2023 Dec; 24(23): 16756. Published online 2023 Nov 25. doi: 10.3390/ijms242316756
PMCID:
PMC10706254
AbstractArticlePDF–8.9M
4.
A Putative Role for TRPC6 in Immune-Mediated Kidney Injury
Daan C. ‘t Hart, Johan van der Vlag, Tom Nijenhuis
Int J Mol Sci. 2023 Nov; 24(22): 16419. Published online 2023 Nov 16. doi: 10.3390/ijms242216419
PMCID:
PMC10671681
AbstractArticlePDF–1.4M
5.
An inactivating human TRPC6 channel mutation without focal segmental glomerulosclerosis
Lilas Batool, Krithika Hariharan, Yao Xu, Mario Kaßmann, Dmitry Tsvetkov, Björn-Oliver Gohlke, Sylvia Kaden, Manfred Gossen, Bernd Nürnberg, Andreas Kurtz, Maik Gollasch
Cell Mol Life Sci. 2023 Sep; 80(9): 265. Published online 2023 Aug 24. doi: 10.1007/s00018-023-04901-w
PMCID:
PMC10449997
AbstractArticlePDF–3.4M
6.
Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells
Tengteng Zhao, Sophia Parmisano, Zahra Soroureddin, Manjia Zhao, Lauren Yung, Patricia A. Thistlethwaite, Ayako Makino, Jason X.-J Yuan
Am J Physiol Cell Physiol. 2022 Oct 1; 323(4): C959–C973. Published online 2022 Aug 15. doi: 10.1152/ajpcell.00313.2022
PMCID:
PMC9485000
AbstractArticle
7.
Klotho Ameliorates Podocyte Injury through Targeting TRPC6 Channel in Diabetic Nephropathy
Xingmei Yao, Hengjiang Guo, Mengyao Sun, Sixuan Meng, Bingbing Zhu, Ji Fang, Jiebo Huang, Hao Wang, Lina Xing
J Diabetes Res. 2022; 2022: 1329380. Published online 2022 Apr 18. doi: 10.1155/2022/1329380
PMCID:
PMC9038427
AbstractArticlePDF–2.9M
8.
OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma
Wei Shao, Zhen-Yu Hao, Yi-Fei Chen, Jun Du, Qian He, Liang-Liang Ren, Yan Gao, Nan Song, Yan Song, Hua He, Yi-Zheng Wang
J Mol Cell Biol. 2021 Jun; 13(6): 409–421. Published online 2021 Jan 28. doi: 10.1093/jmcb/mjab001
PMCID:
PMC8436707
AbstractArticlePDF–1008K
9.
Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple-negative breast cancer cells
Isaac Jardin, Raquel Diez-Bello, Debora Falcon, Sandra Alvarado, Sergio Regodon, Gines M. Salido, Tarik Smani, Juan A. Rosado
J Biol Chem. 2021 Jan-Jun; 296: 100254. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015769
PMCID:
PMC7948746
AbstractArticlePDF–6.3M
10.
Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles
Jian Xie, Sung-Wan An, Xin Jin, Yuan Gui, Chou-Long Huang
PLoS One. 2020; 15(3): e0229799. Published online 2020 Mar 5. doi: 10.1371/journal.pone.0229799
PMCID:
PMC7058344
AbstractArticlePDF–2.9M
11.
Role of TRPC6 in progression of diabetic kidney disease
Alexander Staruschenko, Denisha Spires, Oleg Palygin
Curr Hypertens Rep. Author manuscript; available in PMC 2020 May 21.
Published in final edited form as: Curr Hypertens Rep. 2019 May 21; 21(7): 48. Published online 2019 May 21. doi: 10.1007/s11906-019-0960-9
PMCID:
PMC6814005
AbstractArticlePDF–690K
12.
Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes
Onur K. Polat, Masatoshi Uno, Terukazu Maruyama, Ha Nam Tran, Kayo Imamura, Chee Fah Wong, Reiko Sakaguchi, Mariko Ariyoshi, Kyohei Itsuki, Jun Ichikawa, Takashi Morii, Masahiro Shirakawa, Ryuji Inoue, Katsuhiko Asanuma, Jochen Reiser, Hidehito Tochio, Yasuo Mori, Masayuki X. Mori
J Am Soc Nephrol. 2019 Sep; 30(9): 1587–1603. Published online 2019 Jul 2. doi: 10.1681/ASN.2018070756
PMCID:
PMC6727271
AbstractArticle
13.
Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6
Brianna E. Talbot, David H. Vandorpe, Brian R. Stotter, Seth L. Alper, Johannes S. Schlondorff
J Biol Chem. 2019 Aug 23; 294(34): 12655–12669. Published online 2019 Jul 2. doi: 10.1074/jbc.RA119.008299
PMCID:
PMC6709635
AbstractArticlePDF–2.5M
14.
Soluble klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR-FGF23 pathway
Jon D. Wright, Sung-Wan An, Jian Xie, Carmay Lim, Chou-Long Huang
FASEB J. 2019 Aug; 33(8): 9182–9193. Published online 2019 May 7. doi: 10.1096/fj.201900321R
PMCID:
PMC6662984
AbstractArticle
15.
Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation
Xin Hou, Haitao Xiao, Yanhong Zhang, Xixi Zeng, Mengjun Huang, Xiaoyun Chen, Lutz Birnbaumer, Yanhong Liao
Cell Death Dis. 2018 Oct; 9(10): 1015. Published online 2018 Oct 3. doi: 10.1038/s41419-018-1052-5
PMCID:
PMC6170481
AbstractArticlePDF–2.2M
16.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
17.
Structure of the receptor-activated human TRPC6 and TRPC3 ion channels
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen
Cell Res. 2018 Jul; 28(7): 746–755. Published online 2018 Apr 26. doi: 10.1038/s41422-018-0038-2
PMCID:
PMC6028632
AbstractArticlePDF–2.4M
18.
Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression
Henning Hagmann, Nicole Mangold, Markus M. Rinschen, Tim Koenig, Karl Kunzelmann, Bernhard Schermer, Thomas Benzing, Paul T. Brinkkoetter
FASEB J. 2018 Jan; 32(1): 208–219. Published online 2017 Sep 6. doi: 10.1096/fj.201700309R
PMCID:
PMC5731127
AbstractArticle
19.
Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors
Eun Young Kim, Hila Roshanravan, Stuart E. Dryer
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Sep; 1863(9): 2342–2354. Published online 2017 Jun 16. doi: 10.1016/j.bbadis.2017.06.010
PMCID:
PMC5557291
AbstractArticlePDF–1.5M
20.
TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice
Sayaka Oda, Takuro Numaga-Tomita, Naoyuki Kitajima, Takashi Toyama, Eri Harada, Tsukasa Shimauchi, Akiyuki Nishimura, Tatsuya Ishikawa, Yoshito Kumagai, Lutz Birnbaumer, Motohiro Nishida
Sci Rep. 2017; 7: 7511. Published online 2017 Aug 8. doi: 10.1038/s41598-017-07903-4
PMCID:
PMC5548754
AbstractArticlePDF–7.8M

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