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Select item 109606791.

Blood DNA methylation and liver cancer in American Indians: evidence from the Strong Heart Study

Monique Slowly, Arce Domingo-Relloso, Regina M. Santella, Karin Haack, Daniele M. Fallin, Mary Beth Terry, Dorothy A. Rhoades, Miguel Herreros-Martinez, Esther Garcia-Esquinas, Shelley A. Cole, Maria Tellez-Plaza, Ana Navas-Acien, Hui-Chen Wu

Cancer Causes Control. 2024; 35(4): 661–669. Published online 2023 Nov 27. doi: 10.1007/s10552-023-01822-8

PMCID:: PMC10960679

Abstract Article PDF–617K

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 101461183.

Pan-Cancer Analysis Reveals PPRC1 as a Novel Prognostic Biomarker in Ovarian Cancer and Hepatocellular Carcinoma

Xingqiu Ruan, Guoliang Cui, Changyu Li, Zhiguang Sun

Medicina (Kaunas) 2023 Apr; 59(4): 784. Published online 2023 Apr 17. doi: 10.3390/medicina59040784

PMCID:: PMC10146118

Abstract Article PDF–16M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 93383135.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 92626146.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 83529647.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 58269269.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 573088910.

The E3 ubiquitin ligase APC/C^C^dh1 degrades MCPH1 after MCPH1‐βTrCP2‐Cdc25A‐mediated mitotic entry to ensure neurogenesis

Xiaoqian Liu, Wen Zong, Tangliang Li, Yujun Wang, Xingzhi Xu, Zhong‐Wei Zhou, Zhao‐Qi Wang

EMBO J. 2017 Dec 15; 36(24): 3666–3681. Published online 2017 Nov 17. doi: 10.15252/embj.201694443

PMCID:: PMC5730889

Abstract Article PDF–2.4M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 520725212.

Concerted Action of PGC-1-related Coactivator (PRC) and c-MYC in the Stress Response to Mitochondrial Dysfunction

Natalie Gleyzer, Richard C. Scarpulla

J Biol Chem. 2016 Dec 2; 291(49): 25529–25541. Published online 2016 Oct 27. doi: 10.1074/jbc.M116.719682

PMCID:: PMC5207252

Abstract Article PDF–1.9M

Select item 461721113.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 360562014.

Activation of a PGC-1-related Coactivator (PRC)-dependent Inflammatory Stress Program Linked to Apoptosis and Premature Senescence

Natalie Gleyzer, Richard C. Scarpulla

J Biol Chem. 2013 Mar 22; 288(12): 8004–8015. Published online 2013 Jan 30. doi: 10.1074/jbc.M112.426841

PMCID:: PMC3605620

Abstract Article PDF–1.6M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298654916.

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study

Erwin Reiling, Jana V van Vliet-Ostaptchouk, Esther van 't Riet, Timon W van Haeften, Pascal A Arp, Torben Hansen, Dennis Kremer, Marlous J Groenewoud, Els C van Hove, Johannes A Romijn, Jan W A Smit, Giel Nijpels, Robert J Heine, André G Uitterlinden, Oluf Pedersen, P Eline Slagboom, Johannes A Maassen, Marten H Hofker, Leen M 't Hart, Jacqueline M Dekker

Eur J Hum Genet. 2009 Aug; 17(8): 1056–1062. Published online 2009 Feb 11. doi: 10.1038/ejhg.2009.4

PMCID:: PMC2986549

Abstract Article PDF–115K

Select item 277651217.

Mahatsangy Raharijaona, Soazig Le Pennec, Julie Poirier, Delphine Mirebeau-Prunier, Clothilde Rouxel, Caroline Jacques, Jean-Fred Fontaine, Yves Malthiery, Rémi Houlgatte, Frédérique Savagner

PLoS One. 2009; 4(11): e7964. Published online 2009 Nov 23. doi: 10.1371/journal.pone.0007964

PMCID:: PMC2776512

Abstract Article PDF–1.4M

Select item 265274618.

PGC-1α/β upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations

Sarika Srivastava, John N. Barrett, Carlos T. Moraes

Hum Mol Genet. Author manuscript; available in PMC 2009 Mar 9.

Published in final edited form as: Hum Mol Genet. 2007 Apr 15; 16(8): 993–1005. Published online 2007 Mar 6. doi: 10.1093/hmg/ddm045

PMCID:: PMC2652746

Abstract Article PDF–1007K

Select item 262911619.

Short Hairpin RNA-mediated Silencing of PRC (PGC-1-related Coactivator) Results in a Severe Respiratory Chain Deficiency Associated with the Proliferation of Aberrant Mitochondria

Kristel Vercauteren, Natalie Gleyzer, Richard C. Scarpulla

J Biol Chem. 2009 Jan 23; 284(4): 2307–2319. doi: 10.1074/jbc.M806434200

PMCID:: PMC2629116

Abstract Article PDF–826K

Select item 233535720.

Kristel Vercauteren, Natalie Gleyzer, Richard C. Scarpulla

J Biol Chem. 2008 May 2; 283(18): 12102–12111. doi: 10.1074/jbc.M710150200

PMCID:: PMC2335357

Abstract Article PDF–364K

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