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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 100930542.

Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget’s Disease of Bone

Emily M. Rabjohns, Rishi R. Rampersad, Arin Ghosh, Katlyn Hurst, Amanda M. Eudy, Jaime M. Brozowski, Hyun Ho Lee, Yinshi Ren, Anthony Mirando, Justin Gladman, Jessica L. Bowser, Kathryn Berg, Sachin Wani, Stuart H. Ralston, Matthew J. Hilton, Teresa K. Tarrant

Cells. 2023 Apr; 12(7): 981. Published online 2023 Mar 23. doi: 10.3390/cells12070981

PMCID:: PMC10093054

Abstract Article PDF–3.8M

Select item 97030783.

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions

Katharina M. Glaser, Teresa K. Tarrant, Tim Lämmermann

Front Immunol. 2022; 13: 1039803. Published online 2022 Nov 14. doi: 10.3389/fimmu.2022.1039803

PMCID:: PMC9703078

Abstract Article PDF–20M

Select item 88002434.

G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation

Jaime M. Brozowski, Roman G. Timoshchenko, D. Stephen Serafin, Brittney Allyn, Jessica Koontz, Emily M. Rabjohns, Rishi R. Rampersad, Yinshi Ren, Amanda M. Eudy, Taylor F. Harris, David Abraham, Daniel Mattox, Clinton T. Rubin, Matthew J. Hilton, Janet Rubin, Nancy L. Allbritton, Matthew J. Billard, Teresa K. Tarrant

Stem Cell Res Ther. 2022; 13: 37. Published online 2022 Jan 29. doi: 10.1186/s13287-022-02715-4

PMCID:: PMC8800243

Abstract Article PDF–2.1M

Select item 86488175.

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells

Yanghui Sheng, Lujing Chen, Xiaozhi Ren, Zheng Jiang, King-Wai Yau

Sci Rep. 2021; 11: 23424. Published online 2021 Dec 6. doi: 10.1038/s41598-021-02832-9

PMCID:: PMC8648817

Abstract Article PDF–2.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 61361517.

Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion

Antony D. Abraham, Selena S. Schattauer, Kathryn L. Reichard, Joshua H. Cohen, Harrison M. Fontaine, Allisa J. Song, Salina D. Johnson, Benjamin B. Land, Charles Chavkin

J Neurosci. 2018 Sep 12; 38(37): 8031–8043. doi: 10.1523/JNEUROSCI.0653-18.2018

PMCID:: PMC6136151

Abstract Article PDF–1.3M

Select item 57267908.

MIGRATING MYELOID CELLS SENSE TEMPORAL DYNAMICS OF CHEMOATTRACTANT CONCENTRATIONS

Caren E. Petrie Aronin, Yun Zhao, Justine S. Yoon, Nicole Y. Morgan, Thorsten Prüstel, Ronald N. Germain, Martin Meier-Schellersheim

Immunity. Author manuscript; available in PMC 2018 Nov 21.

Published in final edited form as: Immunity. 2017 Nov 21; 47(5): 862–874.e3. doi: 10.1016/j.immuni.2017.10.020

PMCID:: PMC5726790

Abstract Article PDF–1.0M

Select item 55097409.

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

Brent Wilkinson, Jing Li, Marcelo P. Coba

Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3

PMCID:: PMC5509740

Abstract Article PDF–4.6M

Select item 411986610.

Loss of Morphine Reward and Dependence in Mice Lacking G Protein-Coupled Receptor Kinase 5

Laura Glück, Anastasia Loktev, Lionel Moulédous, Catherine Mollereau, Ping-Yee Law, Stefan Schulz

Biol Psychiatry. Author manuscript; available in PMC 2015 Nov 15.

Published in final edited form as: Biol Psychiatry. 2014 Nov 15; 76(10): 767–774. Published online 2014 Feb 3. doi: 10.1016/j.biopsych.2014.01.021

PMCID:: PMC4119866

Abstract Article PDF–644K

Select item 382860511.

G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses

Teresa K. Tarrant, Matthew J. Billard, Roman G. Timoshchenko, Marcus W. McGinnis, D. Stephen Serafin, Oded Foreman, Denise A. Esserman, Nelson J. Chao, William E. Lento, David M. Lee, Dhavalkumar Patel, David P. Siderovski

J Leukoc Biol. 2013 Dec; 94(6): 1243–1251. doi: 10.1189/jlb.0213097

PMCID:: PMC3828605

Abstract Article

Select item 357241012.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 289505515.

Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

Erica J. Melief, Mayumi Miyatake, Michael R. Bruchas, Charles Chavkin

Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25): 11608–11613. Published online 2010 Jun 3. doi: 10.1073/pnas.1000751107

PMCID:: PMC2895055

Abstract Article PDF–811K

Select item 248143116.

Identification of transcripts with enriched expression in the developing and adult pancreas

Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason

Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99

PMCID:: PMC2481431

Abstract Article PDF–2.2M

Select item 248127217.

Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ-Opioid-Dependent Dysphoria

Michael R. Bruchas, Benjamin B. Land, Megumi Aita, Mei Xu, Sabiha K. Barot, Shuang Li, Charles Chavkin

J Neurosci. 2007 Oct 24; 27(43): 11614–11623. doi: 10.1523/JNEUROSCI.3769-07.2007

PMCID:: PMC2481272

Abstract Article PDF–526K

Select item 237682318.

Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

Mei Xu, Michael Petraschka, Jay P. McLaughlin, Ruth E. Westenbroek, Marc G. Caron, Robert J. Lefkowitz, Traci A. Czyzyk, John E. Pintar, Gregory W. Terman, Charles Chavkin

J Neurosci. 2004 May 12; 24(19): 4576–4584. doi: 10.1523/JNEUROSCI.5552-03.2004

PMCID:: PMC2376823

Abstract Article PDF–762K

Select item 210478019.

Sciatic Nerve Ligation-Induced Proliferation of Spinal Cord Astrocytes Is Mediated by κ Opioid Activation of p38 Mitogen-Activated Protein Kinase

Mei Xu, Michael R. Bruchas, Danielle L. Ippolito, Louis Gendron, Charles Chavkin

J Neurosci. 2007 Mar 7; 27(10): 2570–2581. doi: 10.1523/JNEUROSCI.3728-06.2007

PMCID:: PMC2104780

Abstract Article PDF–750K

Select item 141356820.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

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