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Items: 17

1.
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Boerries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez-Aseguinolaza
EMBO Mol Med. 2024 Jan; 16(1): 112–131. Published online 2024 Jan 5. doi: 10.1038/s44321-023-00008-8
PMCID:
PMC10897483
AbstractArticlePDF–3.2M
2.
In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria
Rebeca Martinez-Turrillas, Angel Martin-Mallo, Saray Rodriguez-Diaz, Natalia Zapata-Linares, Paula Rodriguez-Marquez, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, María E. Calleja-Cervantes, Eduardo Salido, Felipe Prosper, Juan R. Rodriguez-Madoz
Mol Ther Methods Clin Dev. 2022 Jun 9; 25: 137–146. Published online 2022 Mar 16. doi: 10.1016/j.omtm.2022.03.006
PMCID:
PMC8971349
AbstractArticlePDF–2.2M
3.
Dysregulated Oxalate Metabolism Is a Driver and Therapeutic Target in Atherosclerosis
Yuhao Liu, Ying Zhao, Yousef Shukha, Haocheng Lu, Lu Wang, Zhipeng Liu, Cai Liu, Yang Zhao, Huilun Wang, Guizhen Zhao, Wenying Liang, Yanbo Fan, Lin Chang, Arif Yurdagul, Jr., Christopher B. Pattillo, A. Wayne Orr, Michael Aviram, Bo Wen, Minerva T. Garcia-Barrio, Jifeng Zhang, Wanqing Liu, Duxin Sun, Tony Hayek, Y. Eugene Chen, Oren Rom
Cell Rep. Author manuscript; available in PMC 2021 Aug 13.
Published in final edited form as: Cell Rep. 2021 Jul 27; 36(4): 109420. doi: 10.1016/j.celrep.2021.109420
PMCID:
PMC8363062
AbstractArticlePDF–2.7M
4.
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome
Oren Rom, Yuhao Liu, Zhipeng Liu, Ying Zhao, Jianfeng Wu, Alia Ghrayeb, Luis Villacorta, Yanbo Fan, Lin Chang, Lu Wang, Cai Liu, Dongshan Yang, Jun Song, Jason C. Rech, Yanhong Guo, Huilun Wang, Guizhen Zhao, Wenying Liang, Yui Koike, Haocheng Lu, Tomonari Koike, Tony Hayek, Subramaniam Pennathur, Chuanwu Xi, Bo Wen, Duxin Sun, Minerva T. Garcia-Barrio, Michael Aviram, Eyal Gottlieb, Inbal Mor, Wanqing Liu, Jifeng Zhang, Y. Eugene Chen
Sci Transl Med. Author manuscript; available in PMC 2021 Jun 2.
Published in final edited form as: Sci Transl Med. 2020 Dec 2; 12(572): eaaz2841. doi: 10.1126/scitranslmed.aaz2841
PMCID:
PMC7982985
AbstractArticlePDF–3.6M
5.
The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria
Brianna Buchalski, Kyle D Wood, Anil Challa, Sonia Fargue, Ross P Holmes, W Todd Lowther, John Knight
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1; 1866(3): 165633. Published online 2019 Dec 7. doi: 10.1016/j.bbadis.2019.165633
PMCID:
PMC7047938
AbstractArticlePDF–479K
6.
Reduction in Urinary Oxalate Excretion in Mouse Models of Primary Hyperoxaluria by RNA interference Inhibition of Liver Lactate Dehydrogenase Activity.
Kyle D Wood, Ross P. Holmes, David Erbe, Abigail Liebow, Sonia Fargue, John Knight
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1; 1865(9): 2203–2209. Published online 2019 May 2. doi: 10.1016/j.bbadis.2019.04.017
PMCID:
PMC6613992
AbstractArticlePDF–1.1M
7.
In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis
Roberto Pagliarini, Raffaele Castello, Francesco Napolitano, Roberta Borzone, Patrizia Annunziata, Giorgia Mandrile, Mario De Marchi, Nicola Brunetti-Pierri, Diego di Bernardo
Cell Rep. 2016 Jun 7; 15(10): 2292–2300. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.05.014
PMCID:
PMC4906368
AbstractArticle
8.
Metabolism of 13C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase
Xingsheng Li, John Knight, Sonia Fargue, Brianna Buchalski, Zhengrong Guan, Edward W Inscho, Abigail Liebow, Kevin Fitzgerald, William Querbes, W. Todd Lowther, Ross P. Holmes
Biochim Biophys Acta. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2016 Feb; 1862(2): 233–239. Published online 2015 Dec 2. doi: 10.1016/j.bbadis.2015.12.001
PMCID:
PMC4706777
AbstractArticlePDF–1.8M
9.
Hydroxyproline metabolism in mouse models of primary hyperoxaluria
John Knight, Ross P. Holmes, Scott D. Cramer, Tatsuya Takayama, Eduardo Salido
Am J Physiol Renal Physiol. 2012 Mar 15; 302(6): F688–F693. Published online 2011 Dec 21. doi: 10.1152/ajprenal.00473.2011
PMCID:
PMC3311317
AbstractArticle
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
Enteric oxalate elimination is induced and oxalate is normalized in a mouse model of primary hyperoxaluria following intestinal colonization with Oxalobacter
Marguerite Hatch, Altin Gjymishka, Eduardo C. Salido, Milton J. Allison, Robert W. Freel
Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3): G461–G469. Published online 2010 Dec 16. doi: 10.1152/ajpgi.00434.2010
PMCID:
PMC3064122
AbstractArticle
12.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
13.
Alanine–glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer
Eduardo C. Salido, Xiao M. Li, Yang Lu, Xia Wang, Alfredo Santana, Namita Roy-Chowdhury, Armando Torres, Larry J. Shapiro, Jayanta Roy-Chowdhury
Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48): 18249–18254. Published online 2006 Nov 16. doi: 10.1073/pnas.0607218103
PMCID:
PMC1838738
AbstractArticlePDF–572K
14.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
15.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
16.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K
17.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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