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Items: 1 to 20 of 24

1.
PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons
Tao Li, Lili Zhao, Ye Li, Meijuan Dang, Jialiang Lu, Ziwei Lu, Qiao Huang, Yang Yang, Yuxuan Feng, Xiaoya Wang, Yating Jian, Heying Wang, Yingying Guo, Lei Zhang, Yu Jiang, Songhua Fan, Shengxi Wu, Hong Fan, Fang Kuang, Guilian Zhang
Cell Death Dis. 2023 Sep; 14(9): 634. Published online 2023 Sep 26. doi: 10.1038/s41419-023-06135-x
PMCID:
PMC10522625
AbstractArticlePDF–9.1M
2.
PPM1K-regulated impaired catabolism of branched-chain amino acids orchestrates polycystic ovary syndrome
Liangshan Mu, Zhenhong Ye, Junhao Hu, Yurong Zhang, Kai Chen, Haipeng Sun, Rong Li, Weian Mao, Xiaoyu Long, Chunmei Zhang, Yuchen Lai, Jun Liu, Yue Zhao, Jie Qiao
eBioMedicine. 2023 Mar; 89: 104492. Published online 2023 Feb 28. doi: 10.1016/j.ebiom.2023.104492
PMCID:
PMC9986518
AbstractArticlePDF–3.9M
3.
The Role of Elevated Branched-Chain Amino Acids in the Effects of Vertical Sleeve Gastrectomy to Reduce Weight and Improve Glucose Regulation
Nadejda Bozadjieva Kramer, Simon S. Evers, Jae Hoon Shin, Sierra Silverwood, Yibin Wang, Charles F. Burant, Darleen A. Sandoval, Randy J. Seeley
Cell Rep. Author manuscript; available in PMC 2020 Nov 2.
Published in final edited form as: Cell Rep. 2020 Oct 13; 33(2): 108239. doi: 10.1016/j.celrep.2020.108239
PMCID:
PMC7605275
AbstractArticlePDF–3.1M
4.
Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-α pathway-dependent fatty acid oxidation
Yueyang Li, Zhenyu Xiong, Wenjun Yan, Erhe Gao, Hexiang Cheng, Guiling Wu, Yi Liu, Ling Zhang, Congye Li, Shan Wang, Miaomiao Fan, Huishou Zhao, Fuyang Zhang, Ling Tao
Theranostics. 2020; 10(12): 5623–5640. Published online 2020 Apr 27. doi: 10.7150/thno.44836
PMCID:
PMC7196282
AbstractArticlePDF–3.8M
5.
BCAA Catabolic Defect Alters Glucose Metabolism in Lean Mice
Ji Wang, Yunxia Liu, Kun Lian, Xinyi Shentu, Junwei Fang, Jing Shao, Mengping Chen, Yibin Wang, Meiyi Zhou, Haipeng Sun
Front Physiol. 2019; 10: 1140. Published online 2019 Sep 4. doi: 10.3389/fphys.2019.01140
PMCID:
PMC6738029
AbstractArticlePDF–4.2M
6.
Glucose promotes cell growth by suppressing branched-chain amino acid degradation
Dan Shao, Outi Villet, Zhen Zhang, Sung Won Choi, Jie Yan, Julia Ritterhoff, Haiwei Gu, Danijel Djukovic, Danos Christodoulou, Stephen C. Kolwicz, Jr, Daniel Raftery, Rong Tian
Nat Commun. 2018; 9: 2935. Published online 2018 Jul 26. doi: 10.1038/s41467-018-05362-7
PMCID:
PMC6062555
AbstractArticlePDF–3.4M
7.
Defective Branched-Chain Amino Acid (BCAA) Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-reperfusion Injury
Tao Li, Zhen Zhang, Stephen C Kolwicz, Jr, Lauren Abell, Nathan D. Roe, Maengjo Kim, Bo Zhou, Yang Cao, Julia Ritterhoff, Haiwei Gu, Daniel Raftery, Haipeng Sun, Rong Tian
Cell Metab. Author manuscript; available in PMC 2018 Feb 7.
Published in final edited form as: Cell Metab. 2017 Feb 7; 25(2): 374–385. doi: 10.1016/j.cmet.2016.11.005
PMCID:
PMC5301464
AbstractArticlePDF–2.5M
8.
Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure
Haipeng Sun, Kristine C. Olson, Chen Gao, Domenick A. Prosdocimo, Meiyi Zhou, Zhihua Wang, Darwin Jeyaraj, Ji-Youn Youn, Shuxun Ren, Yunxia Liu, Christoph D. Rau, Svati Shah, Olga Ilkayeva, Wen-Jun Gui, Noelle S. William, R. Max Wynn, Christopher B. Newgard, Hua Cai, Xinshu Xiao, David T. Chuang, Paul Christian Schulze, Christopher Lynch, Mukesh K. Jain, Yibin Wang
Circulation. Author manuscript; available in PMC 2017 May 24.
Published in final edited form as: Circulation. 2016 May 24; 133(21): 2038–2049. Published online 2016 Apr 8. doi: 10.1161/CIRCULATIONAHA.115.020226
PMCID:
PMC4879058
AbstractArticlePDF–2.6M
9.
IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland
Shuxun Ren, Gang Lu, Asuka Ota, Z. Hong Zhou, Thomas M. Vondriska, Timothy F. Lane, Yibin Wang
PLoS One. 2014; 9(11): e111606. Published online 2014 Nov 4. doi: 10.1371/journal.pone.0111606
PMCID:
PMC4219728
AbstractArticlePDF–1.3M
10.
Adipose transplant for inborn errors of branched chain amino acid metabolism in mice
Heather A. Zimmerman, Kristine C. Olson, Gang Chen, Christopher J. Lynch
Mol Genet Metab. Author manuscript; available in PMC 2014 Mar 17.
Published in final edited form as: Mol Genet Metab. 2013 Aug; 109(4): 345–353. Published online 2013 May 30. doi: 10.1016/j.ymgme.2013.05.010
PMCID:
PMC3955948
AbstractArticlePDF–810K
11.
PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response
Gang Lu, Asuka Ota, Shuxun Ren, Sarah Franklin, Christoph D. Rau, Peipei Ping, Timothy F. Lane, Z. Hong Zhou, Karen Reue, Aldons J. Lusis, Thomas Vondriska, Yibin Wang
Mol Metab. 2013 Nov; 2(4): 405–416. Published online 2013 Aug 3. doi: 10.1016/j.molmet.2013.07.005
PMCID:
PMC3854994
AbstractArticlePDF–3.2M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Tissue-specific and Nutrient Regulation of the Branched-chain α-Keto Acid Dehydrogenase Phosphatase, Protein Phosphatase 2Cm (PP2Cm)
Meiyi Zhou, Gang Lu, Chen Gao, Yibin Wang, Haipeng Sun
J Biol Chem. 2012 Jul 6; 287(28): 23397–23406. Published online 2012 May 15. doi: 10.1074/jbc.M112.351031
PMCID:
PMC3390616
AbstractArticlePDF–3.0M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
17.
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
Gang Lu, Haipeng Sun, Pengxiang She, Ji-Youn Youn, Sarah Warburton, Peipei Ping, Thomas M. Vondriska, Hua Cai, Christopher J. Lynch, Yibin Wang
J Clin Invest. 2009 Jun 1; 119(6): 1678–1687. Published online 2009 May 1. doi: 10.1172/JCI38151
PMCID:
PMC2689111
AbstractArticlePDF–2.0M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development
Gang Lu, Shuxun Ren, Paavo Korge, Jayoung Choi, Yuan Dong, James Weiss, Carla Koehler, Jau-nian Chen, Yibin Wang
Genes Dev. 2007 Apr 1; 21(7): 784–796. doi: 10.1101/gad.1499107
PMCID:
PMC1838530
AbstractArticlePDF–1.1M
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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