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Select item 109424671.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 108514732.

circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis

Lian Tang, Lin Yuan, Jiyuan Yan, Jianhua Ge, Zhi Lian, Zhong Li

J Orthop Surg Res. 2024; 19: 128. Published online 2024 Feb 7. doi: 10.1186/s13018-024-04610-5

PMCID:: PMC10851473

Abstract Article PDF–5.5M

Select item 106415243.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 104882564.

Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability

Jue Huang, Jie-Gang Yang, Jian-Gang Ren, Hou-Fu Xia, Gao-Hong Chen, Qiu-Yun Fu, Lin-Zhou Zhang, Hai-Ming Liu, Kui-Ming Wang, Qi-Hui Xie, Gang Chen

Int J Mol Sci. 2023 Sep; 24(17): 13103. Published online 2023 Aug 23. doi: 10.3390/ijms241713103

PMCID:: PMC10488256

Abstract Article PDF–7.8M

Select item 104633075.

SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression

Nuno Bastos, Stéphanie A. Castaldo, Bárbara Adem, José C. Machado, Carlos A. Melo, Sonia A. Melo

J Transl Med. 2023; 21: 578. Published online 2023 Aug 28. doi: 10.1186/s12967-023-04448-1

PMCID:: PMC10463307

Abstract Article PDF–1.8M

Select item 103039256.

Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)

Nina Brauer, Yuto Maruta, Miriam Lisci, Katharina Strege, Ilske Oschlies, Hikari Nakamura, Svea Böhm, Kai Lehmberg, Leon Brandhoff, Stephan Ehl, Nima Parvaneh, Wolfram Klapper, Mitsunori Fukuda, Gillian M. Griffiths, Hans Christian Hennies, Tim Niehues, Sandra Ammann

Front Immunol. 2023; 14: 1151166. Published online 2023 Jun 14. doi: 10.3389/fimmu.2023.1151166

PMCID:: PMC10303925

Abstract Article PDF–24M

Select item 102130067.

Rab27a-mediated extracellular vesicle secretion contributes to osteogenesis in periodontal ligament-bone niche communication

Yun Lu, Liru Zhao, Jiaqi Mao, Wen Liu, Wensheng Ma, Bingjiao Zhao

Sci Rep. 2023; 13: 8479. Published online 2023 May 25. doi: 10.1038/s41598-023-35172-x

PMCID:: PMC10213006

Abstract Article PDF–3.0M

Select item 102027868.

抑制RAB27a能够抑制三阴乳腺癌细胞的增殖、侵袭和粘附

王丽, 严志锐, 夏耀雄

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20; 43(4): 560–567. Chinese. doi: 10.12122/j.issn.1673-4254.2023.04.08

PMCID:: PMC10202786

Abstract Article PDF–2.0M

Select item 101870109.

Expression and significant roles of the lncRNA NEAT1/miR‐493‐5p/Rab27A axis in ulcerative colitis

Hecheng Wang, Jiadan Teng, Mingtao Wang, Yuhang Zhang, Xiaoshuang Liu, Zhuya Liu

Immun Inflamm Dis. 2023 May; 11(5): e814. Published online 2023 May 16. doi: 10.1002/iid3.814

PMCID:: PMC10187010

Abstract Article PDF–2.2M

Select item 970062110.

Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding

Timo C. E. Zondag, Lamberto Torralba-Raga, Jan A. M. Van Laar, Maud A. W. Hermans, Arjen Bouman, Iris H. I. M. Hollink, P. Martin Van Hagen, Deborah A. Briggs, Alistair N. Hume, Yenan T. Bryceson

J Clin Immunol. 2022; 42(8): 1685–1695. Published online 2022 Jul 23. doi: 10.1007/s10875-022-01315-4

PMCID:: PMC9700621

Abstract Article PDF–1023K

Select item 965341911.

RAB27A promotes the proliferation and invasion of colorectal cancer cells

Qingyan Li, Huixia Zhao, Weiwei Dong, Na Guan, Yanyan Hu, Zhiyan Zeng, He Zhang, Fengyun Zhang, Qiuwen Li, Jingwen Yang, Wenhua Xiao

Sci Rep. 2022; 12: 19359. Published online 2022 Nov 12. doi: 10.1038/s41598-022-23696-7

Correction in:: Sci Rep. 2023; 13: 734.

PMCID:: PMC9653419

Abstract Article PDF–2.0M

Select item 961516012.

PRR34-AS1 promotes exosome secretion of VEGF and TGF-β via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma

Zhilei Zhang, Ye Zhou, Yuming Jia, Chao Wang, Meng Zhang, Zhuo Xu

J Transl Med. 2022; 20: 491. Published online 2022 Oct 27. doi: 10.1186/s12967-022-03628-9

PMCID:: PMC9615160

Abstract Article PDF–8.3M

Select item 935372813.

RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients With Gastric Cancer

HYO JUNG AN, JONG SIL LEE, JUNG WOOK YANG, MIN HYE KIM, JI MIN NA, DAE HYUN SONG

Cancer Genomics Proteomics. 2022 Sep-Oct; 19(5): 606–613. Published online 2022 Sep 3. doi: 10.21873/cgp.20345

PMCID:: PMC9353728

Abstract Article PDF–2.9M

Select item 915300314.

GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies

Marije Kat, Petra E. Bürgisser, Hans Janssen, Iris M. De Cuyper, Ianina L. Conte, Alistair N. Hume, Tom Carter, Jan Voorberg, Coert Margadant, Ruben Bierings

Blood Adv. 2021 Dec 14; 5(23): 5116–5127. Published online 2021 Dec 6. doi: 10.1182/bloodadvances.2021004827

PMCID:: PMC9153003

Abstract Article PDF–4.4M

Select item 851385315.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 775821617.

Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement

Yuta Ohishi, Sandra Ammann, Vahid Ziaee, Katharina Strege, Miriam Groß, Carla Vazquez Amos, Mohammad Shahrooei, Parisa Ashournia, Anahita Razaghian, Gillian M. Griffiths, Stephan Ehl, Mitsunori Fukuda, Nima Parvaneh

Front Immunol. 2020; 11: 612977. Published online 2020 Dec 10. doi: 10.3389/fimmu.2020.612977

PMCID:: PMC7758216

Abstract Article PDF–4.9M

Select item 775805018.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975