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Select item 104740301.

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy

Hyun-Jun Jang, Yo Han Lee, Tam Dao, Yunju Jo, Keon Woo Khim, Hye-jin Eom, Ju Eun Lee, Yi Jin Song, Sun Sil Choi, Kieun Park, Haneul Ji, Young Chan Chae, Kyungjae Myung, Hongtae Kim, Dongryeol Ryu, Neung Hwa Park, Sung Ho Park, Jang Hyun Choi

Exp Mol Med. 2023 Aug; 55(8): 1720–1733. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01047-4

PMCID:: PMC10474030

Abstract Article PDF–5.1M

Select item 87442572.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 67253943.

Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes

Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo

J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005

PMCID:: PMC6725394

Abstract Article PDF–682K

Select item 66555514.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 66023005.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 62441836.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 58627717.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 56450828.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 55767929.

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis

Siming Li, Lin Mi, Lei Yu, Qi Yu, Tongyu Liu, Guo-Xiao Wang, Xu-Yun Zhao, Jun Wu, Jiandie D. Lin

Proc Natl Acad Sci U S A. 2017 Aug 22; 114(34): E7111–E7120. Published online 2017 Aug 7. doi: 10.1073/pnas.1703494114

PMCID:: PMC5576792

Abstract Article PDF–1.6M

Select item 541675510.

THRAP3 Interacts with HELZ2 and Plays a Novel Role in Adipocyte Differentiation

Akiko Katano-Toki, Tetsurou Satoh, Takuya Tomaru, Satoshi Yoshino, Takahiro Ishizuka, Sumiyasu Ishii, Atsushi Ozawa, Nobuyuki Shibusawa, Takafumi Tsuchiya, Tsugumichi Saito, Hiroyuki Shimizu, Koshi Hashimoto, Shuichi Okada, Masanobu Yamada, Masatomo Mori

Mol Endocrinol. May 1, 2013; 27(5): 769–780. Published online 2013 Mar 22. doi: 10.1210/me.2012-1332

PMCID:: PMC5416755

Abstract Article

Select item 538122611.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 457685812.

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029

PMCID:: PMC4576858

Abstract Article PDF–3.0M

Select item 437446713.

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico

A. Murat Maga, Nicolas Navarro, Michael L. Cunningham, Timothy C. Cox

Front Physiol. 2015; 6: 92. Published online 2015 Mar 26. doi: 10.3389/fphys.2015.00092

PMCID:: PMC4374467

Abstract Article PDF–2.2M

Select item 421518114.

Thrap3 docks on phosphoserine 273 of PPARγ and controls diabetic gene programming

Jang Hyun Choi, Sun-Sil Choi, Eun Sun Kim, Mark P. Jedrychowski, Yong Ryoul Yang, Hyun-Jun Jang, Pann-Ghill Suh, Alexander S. Banks, Steven P. Gygi, Bruce M. Spiegelman

Genes Dev. 2014 Nov 1; 28(21): 2361–2369. doi: 10.1101/gad.249367.114

PMCID:: PMC4215181

Abstract Article PDF–896K

Select item 407349415.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 379175516.

A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery

Laura Lande-Diner, Cyril Boyault, Jin Young Kim, Charles J. Weitz

Proc Natl Acad Sci U S A. 2013 Oct 1; 110(40): 16021–16026. Published online 2013 Sep 16. doi: 10.1073/pnas.1305980110

PMCID:: PMC3791755

Abstract Article PDF–998K

Select item 357241017.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 338306518.

Mapping the Nephronophthisis-Joubert-Meckel-Gruber Protein Network Reveals Ciliopathy Disease Genes and Pathways

Liyun Sang, Julie J. Miller, Kevin C. Corbit, Rachel H. Giles, Matthew J. Brauer, Edgar A. Otto, Lisa M. Baye, Xiaohui Wen, Suzie J. Scales, Mandy Kwong, Erik G. Huntzicker, Mindan K. Sfakianos, Wendy Sandoval, J. Fernando Bazan, Priya Kulkarni, Francesc R. Garcia-Gonzalo, Allen D. Seol, John F. O'Toole, Susanne Held, Heiko M. Reutter, William S. Lane, Muhammad Arshad Rafiq, Abdul Noor, Muhammad Ansar, Akella Radha Rama Devi, Val C. Sheffield, Diane C. Slusarski, John B. Vincent, Daniel A. Doherty, Friedhelm Hildebrandt, Jeremy F. Reiter, Peter K. Jackson

Cell. Author manuscript; available in PMC 2012 Jun 26.

Published in final edited form as: Cell. 2011 May 13; 145(4): 513–528. doi: 10.1016/j.cell.2011.04.019

PMCID:: PMC3383065

Abstract Article PDF–2.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313648220.

Genetic Variations Strongly Influence Phenotypic Outcome in the Mouse Retina

Austin S. Jelcick, Yang Yuan, Barrett D. Leehy, Lakeisha C. Cox, Alexandra C. Silveira, Fang Qiu, Sarah Schenk, Andrew J. Sachs, Margaux A. Morrison, Arne M. Nystuen, Margaret M. DeAngelis, Neena B. Haider

PLoS One. 2011; 6(7): e21858. Published online 2011 Jul 14. doi: 10.1371/journal.pone.0021858

Correction in:: PLoS One. 2011; 6(10): 10.1371/annotation/f375292d-9fc7-4e3c-9dc7-af0aee76fa15.

PMCID:: PMC3136482

Abstract Article PDF–1.4M

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