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Items: 1 to 20 of 158

1.
Crosstalk of protein kinase C ε with Smad2/3 promotes tumor cell proliferation in prostate cancer cells by enhancing aerobic glycolysis
Wanfu Xu, Fangyin Zeng, Songyu Li, Guihuan Li, Xiaoju Lai, Qiming Jane Wang, Fan Deng
Cell Mol Life Sci. 2018 Dec; 75(24): 4583–4598. Published online 2018 Sep 12. doi: 10.1007/s00018-018-2914-9
PMCID:
PMC11105635
AbstractArticlePDF–2.4M
2.
Different regulation of PKC isoenzymes and MAPK by PSK and IL-2 in the proliferative and cytotoxic activities of the NKL human natural killer cell line
Angel García-Lora, Marisol Martinez, Susana Pedrinaci, Federico Garrido
Cancer Immunol Immunother. 2003 Jan; 52(1): 59–64. Published online 2002 Oct 17. doi: 10.1007/s00262-002-0336-9
PMCID:
PMC11034184
AbstractArticlePDF–327K
3.
Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer
Khushbukhat Khan, Sameen Zafar, Yasmin Badshah, Naeem Mahmood Ashraf, Mehak Rafiq, Lubna Danish, Maria Shabbir, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak
J Ovarian Res. 2023; 16: 202. Published online 2023 Oct 13. doi: 10.1186/s13048-023-01292-1
PMCID:
PMC10571360
AbstractArticlePDF–3.2M
4.
Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma
Areeba Rehman, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Janeen H. Trembley, Naeem Mahmood Ashraf, Tayyaba Afsar, Ali Almajwal, Nawaf W. Alruwaili, Ali Alshamari, Tariq Nahar Alanezi, Suhail Razak
BMC Cancer. 2023; 23: 147. Published online 2023 Feb 13. doi: 10.1186/s12885-023-10618-7
PMCID:
PMC9926771
AbstractArticlePDF–1.2M
5.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
6.
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division
Silvia Martini, Khalil Davis, Rupert Faraway, Lisa Elze, Nicola Lockwood, Andrew Jones, Xiao Xie, Neil Q. McDonald, David J. Mann, Alan Armstrong, Jernej Ule, Peter J. Parker
Nat Commun. 2021; 12: 6934. Published online 2021 Nov 26. doi: 10.1038/s41467-021-27189-5
PMCID:
PMC8626422
AbstractArticlePDF–5.6M
7.
Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs
Divya Ram Jayaram, Sigal Frost, Chanan Argov, Vijayasteltar Belsamma Liju, Nikhil Ponnoor Anto, Amitha Muraleedharan, Assaf Ben-Ari, Rose Sinay, Ilan Smoly, Ofra Novoplansky, Noah Isakov, Debra Toiber, Chen Keasar, Moshe Elkabets, Esti Yeger-Lotem, Etta Livneh
Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2018899118. Published online 2021 Sep 30. doi: 10.1073/pnas.2018899118
PMCID:
PMC8501901
AbstractArticlePDF–1.8M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
PKC EPSILON IS REQUIRED FOR KRAS-DRIVEN LUNG TUMORIGENESIS
Rachana Garg, Mariana Cooke, Fernando Benavides, Martín C. Abba, Michelle Cicchini, David M. Feldser, Marcelo G. Kazanietz
Cancer Res. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Cancer Res. 2020 Dec 1; 80(23): 5166–5173. Published online 2020 Sep 29. doi: 10.1158/0008-5472.CAN-20-1300
PMCID:
PMC7962984
AbstractArticlePDF–1.7M
10.
PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells
Mariana Cooke, Martin J. Baker, Marcelo G. Kazanietz, Victoria Casado-Medrano
Small GTPases. 2021; 12(3): 202–208. Published online 2019 Oct 29. doi: 10.1080/21541248.2019.1684785
PMCID:
PMC7939553
AbstractArticlePDF–1.6M
11.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
12.
Overexpression of microRNA-205-5p exerts suppressive effects on stem cell drug resistance in gallbladder cancer by down-regulating PRKCE
Guo-Feng Zhang, Jia-Cheng Wu, Hong-Yong Wang, Wei-Dong Jiang, Ling Qiu
Biosci Rep. 2020 Sep 30; 40(9): BSR20194509. Published online 2020 Sep 29. doi: 10.1042/BSR20194509
PMCID:
PMC7533283
AbstractArticlePDF–1.9M
13.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
14.
Regulation of Autophagy by Protein Kinase C-ε in Breast Cancer Cells
Alakananda Basu
Int J Mol Sci. 2020 Jun; 21(12): 4247. Published online 2020 Jun 15. doi: 10.3390/ijms21124247
PMCID:
PMC7352677
AbstractArticlePDF–3.1M
15.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
16.
Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch
Danilo Ranieri, Monica Nanni, Flavia Persechino, Maria Rosaria Torrisi, Francesca Belleudi
Cell Commun Signal. 2020; 18: 76. Published online 2020 May 19. doi: 10.1186/s12964-020-00582-1
PMCID:
PMC7238605
AbstractArticlePDF–1.5M
17.
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
Jan Balzarini
Nat Rev Microbiol. 2007; 5(8): 583–597. doi: 10.1038/nrmicro1707
PMCID:
PMC7098186
AbstractArticlePDF–1.1M
18.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
19.
α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins
Natalie Ostrerova, Leonard Petrucelli, Matthew Farrer, Nitinkumar Mehta, Peter Choi, John Hardy, Benjamin Wolozin
J Neurosci. 1999 Jul 15; 19(14): 5782–5791. doi: 10.1523/JNEUROSCI.19-14-05782.1999
PMCID:
PMC6783081
AbstractArticlePDF–852K
20.
DISTINCTIVE REQUIREMENT OF PKCε IN THE CONTROL OF Rho GTPases IN EPITHELIAL AND MESENCHYMALLY-TRANSFORMED LUNG CANCER CELLS
Victoria Casado-Medrano, Laura Barrio-Real, Anita Wang, Mariana Cooke, Cynthia Lopez-Haber, Marcelo G. Kazanietz
Oncogene. Author manuscript; available in PMC 2019 Sep 28.
Published in final edited form as: Oncogene. 2019 Jul; 38(27): 5396–5412. Published online 2019 Mar 28. doi: 10.1038/s41388-019-0796-4
PMCID:
PMC6609469
AbstractArticlePDF–2.2M

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