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Select item 90053321.

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity

Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan

Science. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911

PMCID:: PMC9005332

Abstract Article PDF–2.0M

Select item 87489582.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 67423223.

Ligand-Induced Internalization of the p75 Neurotrophin Receptor: A Slow Route to the Signaling Endosome

Francisca C. Bronfman, Marianna Tcherpakov, Thomas M. Jovin, Mike Fainzilber

J Neurosci. 2003 Apr 15; 23(8): 3209–3220. doi: 10.1523/JNEUROSCI.23-08-03209.2003

PMCID:: PMC6742322

Abstract Article PDF–1.2M

Select item 66715294.

Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome

Sébastien Zanella, Françoise Watrin, Saïda Mebarek, Fabienne Marly, Michel Roussel, Catherine Gire, Gwenaëlle Diene, Maïté Tauber, Françoise Muscatelli, Gérard Hilaire

J Neurosci. 2008 Feb 13; 28(7): 1745–1755. doi: 10.1523/JNEUROSCI.4334-07.2008

PMCID:: PMC6671529

Abstract Article PDF–659K

Select item 66708245.

Necdin Regulates p53 Acetylation via Sirtuin1 to Modulate DNA Damage Response in Cortical Neurons

Koichi Hasegawa, Kazuaki Yoshikawa

J Neurosci. 2008 Aug 27; 28(35): 8772–8784. doi: 10.1523/JNEUROSCI.3052-08.2008

PMCID:: PMC6670824

Abstract Article PDF–805K

Select item 66185896.

Necdin Controls Proliferation and Apoptosis of Embryonic Neural Stem Cells in an Oxygen Tension-Dependent Manner

Zhenyu Huang, Kazushiro Fujiwara, Ryohei Minamide, Koichi Hasegawa, Kazuaki Yoshikawa

J Neurosci. 2013 Jun 19; 33(25): 10362–10373. doi: 10.1523/JNEUROSCI.5682-12.2013

PMCID:: PMC6618589

Abstract Article PDF–2.7M

Select item 62407397.

Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs

Duarte Pólvora-Brandão, Mariana Joaquim, Inês Godinho, Domenico Aprile, Ana Rita Álvaro, Isabel Onofre, Ana Cláudia Raposo, Luís Pereira de Almeida, Sofia T Duarte, Simão T da Rocha

Hum Mol Genet. 2018 Dec 1; 27(23): 3999–4011. Published online 2018 Aug 8. doi: 10.1093/hmg/ddy274

PMCID:: PMC6240739

Abstract Article PDF–13M

Select item 58862828.

The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways

Tishani Methsala Wijesuriya, Leentje De Ceuninck, Delphine Masschaele, Matthea R Sanderson, Karin Vanessa Carias, Jan Tavernier, Rachel Wevrick

Hum Mol Genet. 2017 Nov 1; 26(21): 4215–4230. Published online 2017 Aug 14. doi: 10.1093/hmg/ddx311

PMCID:: PMC5886282

Abstract Article PDF–1.1M

Select item 58484949.

Exome analysis of Smith–Magenis-like syndrome cohort identifies de novo likely pathogenic variants

Seth I. Berger, Carla Ciccone, Karen L. Simon, May Christine Malicdan, Thierry Vilboux, Charles Billington, Roxanne Fischer, Wendy J. Introne, Andrea Gropman, Jan K. Blancato, James C. Mullikin, NISC Comparative Sequencing Program, William A. Gahl, Marjan Huizing, Ann C. M. Smith

Hum Genet. Author manuscript; available in PMC 2018 Mar 13.

Published in final edited form as: Hum Genet. 2017 Apr; 136(4): 409–420. Published online 2017 Feb 17. doi: 10.1007/s00439-017-1767-x

PMCID:: PMC5848494

Abstract Article PDF–880K

Select item 580359710.

A genetic locus for paranoia

Bernard Crespi, Silven Read, Iiro Salminen, Peter Hurd

Biol Lett. 2018 Jan; 14(1): 20170694. Published online 2018 Jan 17. doi: 10.1098/rsbl.2017.0694

PMCID:: PMC5803597

Abstract Article PDF–404K

Select item 554225911.

Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer

Yu-Han Hu, Qing Chen, Yan-Xia Lu, Jian-Ming Zhang, Chun Lin, Fan Zhang, Wen-Juan Zhang, Xiao-Min Li, Wei Zhang, Xue-Nong Li

Oncotarget. 2017 Jul 11; 8(28): 46191–46203. Published online 2017 May 3. doi: 10.18632/oncotarget.17580

PMCID:: PMC5542259

Abstract Article PDF–10M

Select item 488219012.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 482308713.

NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms

Hailing Yang, Partha Das, Yinhua Yu, Weiqun Mao, Yan Wang, Keith Baggerly, Ying Wang, Rebecca T. Marquez, Anuja Bedi, Jinsong Liu, David Fishman, Zhen Lu, Robert C. Bast, Jr.

Oncotarget. 2016 Jan 19; 7(3): 3018–3032. Published online 2015 Dec 12. doi: 10.18632/oncotarget.6576

PMCID:: PMC4823087

Abstract Article PDF–11M

Select item 479307814.

Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults

Koichi Hasegawa, Toru Yasuda, Chinatsu Shiraishi, Kazushiro Fujiwara, Serge Przedborski, Hideki Mochizuki, Kazuaki Yoshikawa

Nat Commun. 2016; 7: 10943. Published online 2016 Mar 14. doi: 10.1038/ncomms10943

PMCID:: PMC4793078

Abstract Article PDF–2.8M

Select item 474162415.

Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc

Minnkyong Lee, Sarah M. Beggs, Derek Gildea, Sujata Bupp, Jens Lichtenberg, Niraj S. Trivedi, NISC Comparative Sequencing Program, Ying Hu, David M. Bodine, Nigel P.S. Crawford

Oncotarget. 2015 Oct 13; 6(31): 31557–31568. Published online 2015 Aug 19. doi: 10.18632/oncotarget.5230

PMCID:: PMC4741624

Abstract Article PDF–2.9M

Select item 464794116.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 462835817.

NDN and CD1A are novel prognostic methylation markers in patients with head and neck squamous carcinomas

Shama Virani, Emily Bellile, Carol R. Bradford, Thomas E. Carey, Douglas B. Chepeha, Justin A. Colacino, Joseph I. Helman, Jonathan B. McHugh, Lisa A. Peterson, Maureen A. Sartor, Jeremy MG Taylor, Heather M. Walline, Greg T. Wolf, Laura S. Rozek

BMC Cancer. 2015; 15: 825. Published online 2015 Oct 30. doi: 10.1186/s12885-015-1806-8

PMCID:: PMC4628358

Abstract Article PDF–486K

Select item 450978818.

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

Jennifer M. Doyle, Jinlan Gao, Jiawei Wang, Maojun Yang, Patrick Ryan Potts

Mol Cell. Author manuscript; available in PMC 2015 Jul 21.

Published in final edited form as: Mol Cell. 2010 Sep 24; 39(6): 963–974. doi: 10.1016/j.molcel.2010.08.029

PMCID:: PMC4509788

Abstract Article PDF–1.3M

Select item 399653719.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650