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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 62077562.

Chemically monoubiquitinated PEX5 binds to the components of the peroxisomal docking and export machinery

Vera Hagmann, Stefanie Sommer, Patrick Fabian, Jan Bierlmeier, Nadine van Treel, Henning D. Mootz, Dirk Schwarzer, Jorge E. Azevedo, Gabriele Dodt

Sci Rep. 2018; 8: 16014. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34200-5

PMCID:: PMC6207756

Abstract Article PDF–1.7M

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53593844.

Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line

Femke C. C. Klouwer, Janet Koster, Sacha Ferdinandusse, Hans R. Waterham

Histochem Cell Biol. 2017; 147(4): 537–541. Published online 2016 Dec 24. doi: 10.1007/s00418-016-1532-6

PMCID:: PMC5359384

Abstract Article PDF–575K

Select item 46479415.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 46172116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 44903377.

Revisiting the intraperoxisomal pathway of mammalian PEX7

Tony A. Rodrigues, Cláudia P. Grou, Jorge E. Azevedo

Sci Rep. 2015; 5: 11806. Published online 2015 Jul 3. doi: 10.1038/srep11806

PMCID:: PMC4490337

Abstract Article PDF–1.0M

Select item 44398958.

Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene

Abdullah Çim, Salih Coşkun, Orhan Görükmez, Hatice Yüksel, Ünal Uluca, Erminia Di Pietro, François Plourde, Nancy Elise Braverman

J Clin Res Pediatr Endocrinol. 2015 Mar; 7(1): 69–72. Published online 2015 Mar 5. doi: 10.4274/jcrpe.1835

PMCID:: PMC4439895

Abstract Article PDF–137K

Select item 43352319.

Mechanistic Insights into PTS2-mediated Peroxisomal Protein Import: THE CO-RECEPTOR PEX5L DRASTICALLY INCREASES THE INTERACTION STRENGTH BETWEEN THE CARGO PROTEIN AND THE RECEPTOR PEX7

Markus Kunze, Naila Malkani, Sebastian Maurer-Stroh, Christoph Wiesinger, Johannes A. Schmid, Johannes Berger

J Biol Chem. 2015 Feb 20; 290(8): 4928–4940. Published online 2014 Dec 23. doi: 10.1074/jbc.M114.601575

PMCID:: PMC4335231

Abstract Article PDF–2.2M

Select item 413558010.

A PEX7-Centered Perspective on the Peroxisomal Targeting Signal Type 2-Mediated Protein Import Pathway

Tony A. Rodrigues, Inês S. Alencastre, Tânia Francisco, Pedro Brites, Marc Fransen, Cláudia P. Grou, Jorge E. Azevedo

Mol Cell Biol. 2014 Aug; 34(15): 2917–2928. doi: 10.1128/MCB.01727-13

PMCID:: PMC4135580

Abstract Article PDF–1.7M

Select item 324799911.

Two Proteases, Trypsin Domain-containing 1 (Tysnd1) and Peroxisomal Lon Protease (PsLon), Cooperatively Regulate Fatty Acid β-Oxidation in Peroxisomal Matrix

Kanji Okumoto, Yukari Kametani, Yukio Fujiki

J Biol Chem. 2011 Dec 30; 286(52): 44367–44379. Published online 2011 Oct 14. doi: 10.1074/jbc.M111.285197

PMCID:: PMC3247999

Abstract Article PDF–3.0M

Select item 324798512.

Structural Requirements for Interaction of Peroxisomal Targeting Signal 2 and Its Receptor PEX7

Markus Kunze, Georg Neuberger, Sebastian Maurer-Stroh, Jianmin Ma, Thomas Eck, Nancy Braverman, Johannes A. Schmid, Frank Eisenhaber, Johannes Berger

J Biol Chem. 2011 Dec 30; 286(52): 45048–45062. Published online 2011 Nov 5. doi: 10.1074/jbc.M111.301853

PMCID:: PMC3247985

Abstract Article PDF–4.4M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516814.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 290133615.

Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen, Lene Christiansen, Andrew Carl Lidral, Jeffrey Clark Murray

PLoS One. 2010; 5(7): e11493. Published online 2010 Jul 9. doi: 10.1371/journal.pone.0011493

PMCID:: PMC2901336

Abstract Article PDF–778K

Select item 277583216.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014