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Items: 1 to 20 of 38

1.
Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
Eva Cloots, Phaedra Guilbert, Mathias Provost, Lisa Neidhardt, Evelien Van de Velde, Farzaneh Fayazpour, Delphine De Sutter, Savvas N Savvides, Sven Eyckerman, Sophie Janssens
EMBO J. 2024 Mar; 43(5): 695–718. Published online 2023 Dec 20. doi: 10.1038/s44318-023-00015-y
PMCID:
PMC10907643
AbstractArticlePDF–4.4M
2.
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
Monica Viladomiu, Manirath Khounlotham, Belgin Dogan, Svetlana F. Lima, Ahmed Elsaadi, Emre Cardakli, Jim G. Castellanos, Charles Ng, Jeremy Herzog, Alexi A. Schoenborn, Melissa Ellermann, Bo Liu, Shiying Zhang, Ajay S. Gulati, R. Balfour Sartor, Kenneth W. Simpson, Steven M. Lipkin, Randy S. Longman
Cell Rep. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Cell Rep. 2022 Nov 15; 41(7): 111637. doi: 10.1016/j.celrep.2022.111637
PMCID:
PMC9805753
AbstractArticlePDF–2.4M
3.
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease
Ahmad A. Al-Shaibi, Ussama M. Abdel-Motal, Satanay Z. Hubrack, Alex N. Bullock, Amna A. Al-Marri, Nourhen Agrebi, Abdulrahman A. Al-Subaiey, Nazira A. Ibrahim, Adrian K. Charles, COLORS in IBD-Qatar Study Group, Mamoun Elawad, Holm H. Uhlig, Bernice Lo
Cell Mol Gastroenterol Hepatol. 2021; 12(5): 1809–1830. Published online 2021 Jul 6. doi: 10.1016/j.jcmgh.2021.07.001
Correction in:
Cell Mol Gastroenterol Hepatol. 2024; 17(4): 670.
PMCID:
PMC8551217
AbstractArticlePDF–17M
4.
Anterior gradient 2 increases long-chain fatty acid uptake via stabilizing FABP1 and facilitates lipid accumulation
Yunqiu Wang, Mengqi Jia, Chuanjie Liang, Nan Sheng, Xiaodan Wang, Fang Wang, Yanhai Luo, Jin Jiang, Liangyu Cai, Huanmin Niu, Deyu Zhu, Effat Un Nesa, Charles YF Young, Huiqing Yuan
Int J Biol Sci. 2021; 17(3): 834–847. Published online 2021 Feb 8. doi: 10.7150/ijbs.57099
PMCID:
PMC7975708
AbstractArticlePDF–4.0M
5.
WNT/RYK signaling restricts goblet cell differentiation during lung development and repair
Hyun-Taek Kim, Wenguang Yin, Yuko Nakamichi, Paolo Panza, Beate Grohmann, Carmen Buettner, Stefan Guenther, Clemens Ruppert, Yasuhiro Kobayashi, Andreas Guenther, Didier Y. R. Stainier
Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25697–25706. Published online 2019 Nov 27. doi: 10.1073/pnas.1911071116
PMCID:
PMC6926051
AbstractArticlePDF–2.9M
6.
Paracrine signalling of AGR2 stimulates RhoA function in fibroblasts and modulates cell elongation and migration
Hitesh Bhagavanbhai Mangukiya, Hema Negi, Siva Bharath Merugu, Qudsia Sehar, Dhahiri Saidi Mashausi, Fakhar-Un-Nisa Yunus, Zhenghua Wu, Dawei Li
Cell Adh Migr. 2019; 13(1): 332–344. Published online 2019 Nov 11. doi: 10.1080/19336918.2019.1685928
PMCID:
PMC6844563
AbstractArticlePDF–2.2M
7.
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation
Marion Maurel, Joanna Obacz, Tony Avril, Yong‐Ping Ding, Olga Papadodima, Xavier Treton, Fanny Daniel, Eleftherios Pilalis, Johanna Hörberg, Wenyang Hou, Marie‐Claude Beauchamp, Julien Tourneur‐Marsille, Dominique Cazals‐Hatem, Lucia Sommerova, Afshin Samali, Jan Tavernier, Roman Hrstka, Aurélien Dupont, Delphine Fessart, Frédéric Delom, Martin E Fernandez‐Zapico, Gregor Jansen, Leif A Eriksson, David Y Thomas, Loydie Jerome‐Majewska, Ted Hupp, Aristotelis Chatziioannou, Eric Chevet, Eric Ogier‐Denis
EMBO Mol Med. 2019 Jun; 11(6): e10120. Published online 2019 Apr 30. doi: 10.15252/emmm.201810120
PMCID:
PMC6554669
AbstractArticlePDF–3.4M
8.
ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation
L Dumartin, W Alrawashdeh, S M Trabulo, T P Radon, K Steiger, R M Feakins, M P di Magliano, C Heeschen, I Esposito, N R Lemoine, T Crnogorac-Jurcevic
Oncogene. 2017 Jun 1; 36(22): 3094–3103. Published online 2016 Dec 12. doi: 10.1038/onc.2016.459
PMCID:
PMC5467015
AbstractArticlePDF–3.5M
9.
Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration
Dariusz Wodziak, Aiwen Dong, Michael F. Basin, Anson W. Lowe
PLoS One. 2016; 11(10): e0164968. Published online 2016 Oct 20. doi: 10.1371/journal.pone.0164968
PMCID:
PMC5072742
AbstractArticlePDF–2.9M
10.
The Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway
Luke R. Bonser, Bradley W. Schroeder, Lisa A. Ostrin, Nathalie Baumlin, Jean L. Olson, Matthias Salathe, David J. Erle
Am J Respir Cell Mol Biol. 2015 Oct; 53(4): 536–543. doi: 10.1165/rcmb.2014-0318OC
PMCID:
PMC4742895
AbstractArticlePDF–1.2M
11.
Epidermal Growth Factor Receptor (EGFR) Signaling Requires a Specific Endoplasmic Reticulum Thioredoxin for the Post-translational Control of Receptor Presentation to the Cell Surface
Aiwen Dong, Dariusz Wodziak, Anson W. Lowe
J Biol Chem. 2015 Mar 27; 290(13): 8016–8027. Published online 2015 Feb 9. doi: 10.1074/jbc.M114.623207
PMCID:
PMC4375459
AbstractArticlePDF–3.2M
12.
Lung mesenchymal expression of Sox9 plays a critical role in tracheal development
Gianluca Turcatel, Nicole Rubin, Douglas B Menke, Gary Martin, Wei Shi, David Warburton
BMC Biol. 2013; 11: 117. Published online 2013 Nov 25. doi: 10.1186/1741-7007-11-117
PMCID:
PMC4222279
AbstractArticlePDF–4.9M
13.
AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus
Joakim H. Bergström, Katarina A. Berg, Ana M. Rodríguez-Piñeiro, Bärbel Stecher, Malin E. V. Johansson, Gunnar C. Hansson
PLoS One. 2014; 9(8): e104186. Published online 2014 Aug 11. doi: 10.1371/journal.pone.0104186
PMCID:
PMC4128659
AbstractArticlePDF–5.4M
14.
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm
Jianwen Que, Tadashi Okubo, James R. Goldenring, Ki-Taek Nam, Reiko Kurotani, Edward E. Morrisey, Olena Taranova, Larysa H. Pevny, Brigid L. M. Hogan
Development. Author manuscript; available in PMC 2013 Apr 14.
Published in final edited form as: Development. 2007 Jul; 134(13): 2521–2531. Published online 2007 May 23. doi: 10.1242/dev.003855
PMCID:
PMC3625644
AbstractArticlePDF–3.0M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Loss of Anterior Gradient 2 (Agr2) Expression Results in Hyperplasia and Defective Lineage Maturation in the Murine Stomach
Aparna Gupta, Dariusz Wodziak, May Tun, Donna M. Bouley, Anson W. Lowe
J Biol Chem. 2013 Feb 8; 288(6): 4321–4333. Published online 2012 Dec 3. doi: 10.1074/jbc.M112.433086
PMCID:
PMC3567683
AbstractArticlePDF–6.7M
17.
AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia
A.M. Norris, A. Gore, A. Balboni, A. Young, D.S. Longnecker, M. Korc
Oncogene. Author manuscript; available in PMC 2014 Feb 15.
Published in final edited form as: Oncogene. 2013 Aug 15; 32(33): 3867–3876. Published online 2012 Sep 3. doi: 10.1038/onc.2012.394
PMCID:
PMC3515713
AbstractArticlePDF–2.1M
18.
The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways
Olivier Boucherat, Jamila Chakir, Lucie Jeannotte
Biol Open. 2012 Jul 15; 1(7): 677–691. Published online 2012 May 29. doi: 10.1242/bio.20121701
PMCID:
PMC3507293
AbstractArticlePDF–11M
19.
The estrogen-responsive Agr2 gene regulates mammary epithelial proliferation and facilitates lobuloalveolar development
Suman Verma, Michael L. Salmans, Mikhail Geyfman, Hong Wang, Zhengquan Yu, Zhongxian Lu, Fang Zhao, Steven M. Lipkin, Bogi Andersen
Dev Biol. Author manuscript; available in PMC 2013 Sep 15.
Published in final edited form as: Dev Biol. 2012 Sep 15; 369(2): 249–260. Published online 2012 Jul 20. doi: 10.1016/j.ydbio.2012.06.030
PMCID:
PMC3465459
AbstractArticlePDF–2.0M
20.
NeuroD1 is required for survival of photoreceptors but not pinealocytes: Results from targeted gene deletion studies
Margaret J. Ochocinska, Estela M. Muñoz, Shobi Veleri, Joan L. Weller, Steven L. Coon, Nikita Pozdeyev, P. Michael Iuvone, Sandra Goebbels, Takahisa Furukawa, David C. Klein
J Neurochem. Author manuscript; available in PMC 2013 Oct 1.
Published in final edited form as: J Neurochem. 2012 Oct; 123(1): 44–59. Published online 2012 Aug 16. doi: 10.1111/j.1471-4159.2012.07870.x
PMCID:
PMC3441145
AbstractArticlePDF–4.5M

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