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Select item 95071271.

PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells

Gina M LoMastro, Chelsea G Drown, Aubrey L Maryniak, Cayla E Jewett, Margaret A Strong, Andrew Jon Holland

eLife. 2022; 11: e80643. Published online 2022 Aug 15. doi: 10.7554/eLife.80643

PMCID:: PMC9507127

Abstract Article PDF–13M

Select item 94808572.

Centriole signaling restricts hepatocyte ploidy to maintain liver integrity

Valentina C. Sladky, Hanan Akbari, Daniel Tapias-Gomez, Lauren T. Evans, Chelsea G. Drown, Margaret A. Strong, Gina M. LoMastro, Tatianna Larman, Andrew J. Holland

Genes Dev. 2022 Jul 1; 36(13-14): 843–856. doi: 10.1101/gad.349727.122

PMCID:: PMC9480857

Abstract Article PDF–12M

Select item 92960053.

Upstream open reading frames control PLK4 translation and centriole duplication in primordial germ cells

Thao P. Phan, Christina A. Boatwright, Chelsea G. Drown, Marnie W. Skinner, Margaret A. Strong, Philip W. Jordan, Andrew J. Holland

Genes Dev. 2022 Jun 1; 36(11-12): 718–736. doi: 10.1101/gad.349604.122

PMCID:: PMC9296005

Abstract Article PDF–21M

Select item 92366124.

Global cellular response to chemical perturbation of PLK4 activity and abnormal centrosome number

Johnny M Tkach, Reuben Philip, Amit Sharma, Jonathan Strecker, Daniel Durocher, Laurence Pelletier

eLife. 2022; 11: e73944. Published online 2022 Jun 27. doi: 10.7554/eLife.73944

PMCID:: PMC9236612

Abstract Article PDF–2.4M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 56748737.

Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

Leah Bury, Paula A. Coelho, Angela Simeone, Samantha Ferries, Claire E. Eyers, Patrick A. Eyers, Magdalena Zernicka-Goetz, David M. Glover

J Cell Biol. 2017 Nov 6; 216(11): 3571–3590. doi: 10.1083/jcb.201606077

PMCID:: PMC5674873

Abstract Article PDF–4.1M

Select item 47808218.

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression

Jillian J. Goetz, Lauren A. Laboissonniere, Andrea K. Wester, Madison R. Lynch, Jeffrey M. Trimarchi

PLoS One. 2016; 11(3): e0150878. Published online 2016 Mar 7. doi: 10.1371/journal.pone.0150878

PMCID:: PMC4780821

Abstract Article PDF–30M

Select item 46555149.

Epidermal development, growth control, and homeostasis in the face of centrosome amplification

Anita Kulukian, Andrew J. Holland, Benjamin Vitre, Shruti Naik, Don W. Cleveland, Elaine Fuchs

Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46): E6311–E6320. Published online 2015 Nov 2. doi: 10.1073/pnas.1518376112

PMCID:: PMC4655514

Abstract Article PDF–2.0M

Select item 460075410.

Loss of KLF14 triggers centrosome amplification and tumorigenesis

Guangjian Fan, Lianhui Sun, Peipei Shan, Xianying Zhang, Jinliang Huan, Xiaohong Zhang, Dali Li, Tingting Wang, Tingting Wei, Xiaohong Zhang, Xiaoyang Gu, Liangfang Yao, Yang Xuan, Zhaoyuan Hou, Yongping Cui, Liu Cao, Xiaotao Li, Shengping Zhang, Chuangui Wang

Nat Commun. 2015; 6: 8450. Published online 2015 Oct 6. doi: 10.1038/ncomms9450

PMCID:: PMC4600754

Abstract Article PDF–1.9M

Select item 449987111.

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

Marko Marjanovic, Carlos Sánchez-Huertas, Berta Terré, Rocío Gómez, Jan Frederik Scheel, Sarai Pacheco, Philip A. Knobel, Ana Martínez-Marchal, Suvi Aivio, Lluís Palenzuela, Uwe Wolfrum, Peter J. McKinnon, José A. Suja, Ignasi Roig, Vincenzo Costanzo, Jens Lüders, Travis H. Stracker

Nat Commun. Author manuscript; available in PMC 2016 Jan 9.

Published in final edited form as: Nat Commun. 2015; 6: 7676. Published online 2015 Jul 9. doi: 10.1038/ncomms8676

PMCID:: PMC4499871

Abstract Article PDF–3.4M

Select item 409414912.

Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling

Moe R. Mahjoub, Tim Stearns

Curr Biol. Author manuscript; available in PMC 2014 Jul 11.

Published in final edited form as: Curr Biol. 2012 Sep 11; 22(17): 1628–1634. Published online 2012 Jul 26. doi: 10.1016/j.cub.2012.06.057

PMCID:: PMC4094149

Abstract Article PDF–453K

Select item 390926813.

p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress

Alejandra Ward, John W. Hudson

PLoS One. 2014; 9(1): e87918. Published online 2014 Jan 31. doi: 10.1371/journal.pone.0087918

PMCID:: PMC3909268

Abstract Article PDF–1.6M

Select item 389871014.

Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles

Paula A. Coelho, Leah Bury, Bedra Sharif, Maria G. Riparbelli, Jingyan Fu, Giuliano Callaini, David M. Glover, Magdalena Zernicka-Goetz

Dev Cell. 2013 Dec 9; 27(5): 586–597. doi: 10.1016/j.devcel.2013.09.029

PMCID:: PMC3898710

Abstract Article

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 353339116.

Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes

Philip W. Jordan, Jesse Karppinen, Mary A. Handel

J Cell Sci. 2012 Nov 1; 125(21): 5061–5072. doi: 10.1242/jcs.105015

PMCID:: PMC3533391

Abstract Article

Select item 335854117.

ENU Mutagenesis in Mice Identifies Candidate Genes For Hypogonadism

Jeffrey Weiss, Lisa A. Hurley, Rebecca M. Harris, Courtney Finlayson, Minghan Tong, Lisa A. Fisher, Jennifer L. Moran, David R. Beier, Christopher Mason, J. Larry Jameson

Mamm Genome. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Mamm Genome. 2012 Jun; 23(5-6): 346–355. Published online 2012 Jan 19. doi: 10.1007/s00335-011-9388-5

PMCID:: PMC3358541

Abstract Article PDF–2.7M

Select item 335054918.

Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis

Andrew J. Holland, Daniele Fachinetti, Sandrine Da Cruz, Quan Zhu, Benjamin Vitre, Mariana Lince-Faria, Denaly Chen, Nicole Parish, Inder M. Verma, Monica Bettencourt-Dias, Don W. Cleveland

Mol Biol Cell. 2012 May 15; 23(10): 1838–1845. doi: 10.1091/mbc.E11-12-1043